Strain:

129S2/SvHsd

Produced in:

U.K.

Research use:

Ovary transplant and ova transfer studies, Production of targeted mutations due to the availability of several lines of embryonic stem cells

Strain:

HsdSage:LE-5HT3a^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

A/JOlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Behavior, Carcinogenesis, General studies, Teratogenesis

Strain:

ACI/SegHsd

Produced in:

U.S. Cryopreserved

Research use:

Carcinogenesis, Estrogen-induced pituitary growth, Transplant immunology

Strain:

HsdSage:SD-Ahr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Obesity, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-SNCA^{em1(SNCA-A53T)Sage}

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-SNCA^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-ApoE^em1Sage

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, General studies, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases

Strain:

HsdSage:SD-App^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

Strain:

Hsd:Athymic Nude-Foxn1^nu, Hsd:Athymic Nude-Foxn1^nu/Foxn1⁺

Produced in:

U.S., U.K., The Netherlands

Research use:

Autoimmune disease, Gene therapy, General studies, Imaging, Immunology, Oncology, Surgical, Transplantation, Tumor Cell Growth, Tumor growth, Sentinel model - Heterozygous Hsd:Athymic Nude-Foxn1nu/Foxn1+

Strain:

Hsd:RH-Foxn1^rnu, Hsd:RH-Foxn1^rnu/Foxn1⁺

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Oncology, Transplantation, Sentinel model – Heterozygous Hsd:RH-Foxn1rnu/Foxn1+

Strain:

NOD.CB17-Prkdc^scidIl2rg^tm1B2m^tm1Fcgrt^tm1(B2m)/BcgenHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

General studies, Oncology, Humanization applications, Graft vs. host disease research, Drug efficacy evaluation

Strain:

NOD.CB17-Prkdc^scidIl2rg^tm1Il15^tm1(IL15)/BcgenHsd

Produced in:

U.S., The Netherlands

Research use:

Immunotherapy, Oncology research, Infectious disease, Humanization applications, NK cell role in tumorigenesis, Antibody drug efficacy evaluation

Strain:

NOD.CB17-Prkdc^scid IL2rg^tm1/BcgenHsd

Produced in:

U.S., The Netherlands

Research use:

Aging, Chemoresistance, General studies, Immunotherapy, Oncology, Stem cells, Tumor Cell Growth, Tumor growth, Humanization applications, Infectious disease

Strain:

B6C3F1/Hsd, B6C3F1/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Toxicology, Carcinogenicity, Embryo donors, Toxicology

Strain:

B6CBAF1/OlaHsd

Produced in:

The Netherlands

Strain:

B6D2F1/Hsd, B6D2F1/JRccHsd

Produced in:

U.S., The Netherlands

Research use:

Behavior, Bioassay of nutrients, drugs, and hormones, Tumorigenicity

Strain:

BALB/cOlaHsd, BALB/cAnNHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Antibody production, Cardiovascular, COVID-19, General studies, Infectious disease, Monoclonal antibodies, Oncology, Pharmacology, Teratology, Toxicology, Transplantation, General purpose

Strain:

BALB/cAnNHsd (BP)

Produced in:

U.S., U.K. Biosecure Plus™

Research use:

Aging, Antibody production, Cardiovascular, COVID-19, General studies, Infectious disease, Monoclonal antibodies, Oncology, Pharmacology, Teratology, Toxicology, Transplantation, General purpose

Strain:

BALB/cOlaHsd-Foxn1^nu, BALB/cOlaHsd-Foxn1^nu/Foxn1⁺

Produced in:

U.K., The Netherlands

Research use:

Imaging, Immunology, Oncology, Transplantation, Tumor growth, Antibody production, Autoimmune disease, Sentinel model - Heterozygous BALB/cOlaHsd-Foxn1nu/Foxn1+

Strain:

HsdSage:SD-Abcg2^em1Sage

Produced in:

U.S.

Research use:

ADMET, Tissue distribution, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

Strain:

HsdSage:SD-Bdnf^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Metabolism, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

Strain:

BN/RijHsd

Produced in:

U.S., U.K.

Research use:

Aging, General studies, Oncology, Transplantation, Allergic Respiratory Disease, Leukemia, Nephrology

Strain:

HsdSage:SD-Abcb11^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

Strain:

C3H/HeNHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Ocular disease

Strain:

C57BL/6JRccHsd Aged

Produced in:

The Netherlands

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Osteoarthritis, Neoplasia, Neurobiology, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

C57BL/6BrdCrHsd-Tyr^c

Produced in:

U.S., U.K., The Netherlands

Research use:

Ovarian transfer, Source of albino C57BL/6 embryos for chimera generation

Strain:

C57BL/6JOlaHsd, C57BL/6JRccHsd, C57BL/6NHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Alcoholism, Alpha Synuclein, Background for Genetically Engineered Mouse Models, Behavior, Behavioral and learning disabilities, Cardiovascular, COVID-19, Diabetes type 2, Diet induced obesity, Drug Addiction, General studies, Genetically modified, Immunology, Infectious disease, Neuroscience, Oncology, Osteoporosis, Surgical, Toxicology, Vaccines, Background for induced and genetically-modified models, Behavior and learning disabilities, Diet-induced obesity, Drug addiction, Superovulation

Strain:

C57BL/6NHsd (BP)

Produced in:

U.S., U.K. Biosecure Plus™

Research use:

Aging, Alcoholism, Alpha Synuclein, Behavior, Behavioral and learning disabilities, Cardiovascular, COVID-19, Diabetes type 2, Diet induced obesity, General studies, Genetically modified, Immunology, Infectious disease, Neuroscience, Oncology, Osteoporosis, Surgical, Toxicology, Vaccines, Background for induced and genetically-modified models, Behavior and learning disabilities, Diet-induced obesity, Drug addiction, Superovulation

Strain:

C57BL/KaLwRijHsd

Produced in:

The Netherlands

Strain:

HsdSage:SD-Cacna1c^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Neurodegeneration, Neuropathology, Neuroscience, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Synaptic formation and repair

Strain:

HsdSage:LE-CAMKIIA^{em1(IRES-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-NR1I3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

Strain:

CB6F1/Hsd, CB6F1/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

Behavior, Immunology, Infection, Reproductive Biology

Strain:

CBA/JCrHsd

Produced in:

U.S.

Research use:

General studies, Immunology, Only approved mouse strain for use in the Local Lymph Node Assay, a refined alternative research method for evaluating the allergic contact dermatitis potential of chemicals and compounds

Strain:

CBA/CaOlaHsd

Produced in:

U.K., The Netherlands

Research use:

General studies, Hearing

Strain:

CD2F1/Hsd

Produced in:

U.S.

Research use:

Carcinogenesis, Pharmacology

Strain:

HsdSage:SD-Cftr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

Strain:

HsdSage:SD-CHD8^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neuroscience

Strain:

HsdSage:SD-Chrna7^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Cntnap2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

Strain:

Hsd:Cotton Rat

Produced in:

U.S.

Research use:

Infectious disease, Measles, Parainfluenza Type 3, Adenoviral vector-based gene therap, Herpes Simplex, Human metapneumovirus, Monkeypox, Mycobacterium tuberculosis, Polio, COVID-19

Strain:

HsdSage:SD-Cox1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Cox2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

M. fascicularis

Produced in:

U.S.

Research use:

Cellular therapies, COVID-19, Diabetes, General studies, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology

Strain:

DA/OlaHsd

Produced in:

U.S., U.K.

Research use:

Cardiovascular Experimental allergic encephalomyelitis, Induced rheumatoid arthritis, Oncology, Transplantation

Strain:

SR/JrHsd, SS/JrHsd

Produced in:

U.S. Cryopreserved

Research use:

Heart failure, Nephropathy, Salt-sensitive hypertension, Stroke

Strain:

DBA/1OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Adjuvant-induced arthritis, Immunology, Inflammation

Strain:

DBA/2JRccHsd, DBA/2NHsd, DBA/2OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Audiogenic seizures, Progressive hearing loss

Strain:

BKS.Cg-+Lepr^db/+Lepr^db/OlaHsd, BKS.Cg-Dock7^m+/+Lepr^db/OlaHsd, BKS.Cg-Dock7^m +/Dock7^m+/OlaHsd, BKS.Cg-(Lean)/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Obesity, Immunodeficiency, Peripheral neuropathy

Strain:

HsdSage:SD-Disc1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Bipolar disorder, Neuronal growth and transport studies, Schizophrenia

Strain:

HsdSage:SD-Slc6a3^{em1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage: LE-Slc6a3^{em1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdDhl:DH

Produced in:

The Netherlands

Research use:

Cardiovascular, General studies, Ocular studies, Pharmacology, Toxicology, Auditory Studies

Strain:

HsdHaz:(DB) SPF

Produced in:

U.S.

Research use:

General studies, Immunology, Neuroscience, Pharmacology, Teratology, Toxicology

Strain:

HsdSage:SD-Faah^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

Strain:

F344/NHsd Aged

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Oncology, Ophthalmology, Toxicology, Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

F344/NHsd

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Infectious disease, Oncology, Ophthalmology, Surgical, Toxicology

Strain:

HsdSage: SD-Fmr1-/null^em1Sage, HsdSage:SD-Fmr1+/-^em1Sage, HsdSage:SD-Fmr1^em1Sage

Produced in:

U.S.

Research use:

Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

Strain:

FVB/NHan^®Hsd, FVB/NHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Transgenic model development

Strain:

HsdSage:SD-Gabrb3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

Strain:

HsdHan^®:AURA

Produced in:

U.S.

Research use:

Behavior, Carcinogenicity, COVID-19, Infectious disease, Metabolism, Oncology, Surgical, Toxicology, Hibernation, Hypercholesterolemia, Syrian Hamster Embryo (SHE) Cell Transformation Assay

Strain:

HsdSage:SD-ApoE2^{em1(hApoE2)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE3^{em1(hApoE3)Sage}

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE4^{em1(hApoE4)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Cardiovascular, Neuroscience, Neurodegenerative diseases

Strain:

HsdHot:Holtzman^® SD^®

Produced in:

U.S.

Research use:

General studies, Neurology, Oncology, Reproduction, Teratology, Toxicology

Strain:

C57BL/6Hsd-Ace2^em1(ACE2)Env

Produced in:

U.S.

Research use:

Cardiovascular, Infectious disease, COVID-19

Strain:

Hsd:SD-Ace2^em1(ACE2)Env

Produced in:

U.S.

Research use:

Cardiovascular, Infectious disease, COVID-19

Strain:

C57BL/6Hsd-Ace2^em1(ACE2)EnvTmprss2^{em1(TMPRSS2)Env}

Produced in:

U.S. Cryopreserved

Research use:

Infectious disease, COVID-19

Strain:

C57BL/6Hsd-Tmprss2^{em1(TMPRSS2)Env}

Produced in:

U.S.

Research use:

Oncology, Infectious disease, COVID-19

Strain:

Hsd:ICR (CD-1^®)

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, COVID-19, General studies, Infectious disease, Oncology, Teratology, Toxicology, Vaccines

Strain:

HsdSage:SD-Ldlr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lep^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

Strain:

LEW/SsNHsd

Produced in:

U.S.

Research use:

Adjuvant-induced arthritis, Experimental allergic encephalomyelitis, General studies, Immunology, Oncology, Preclinical (PK/PD), Surgical, Transplantation, Adjuvant-induced arthritis

Strain:

HsdSage:SD-Lgals1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdOla:LH

Produced in:

U.K., The Netherlands

Research use:

Behavior

Strain:

HsdBlu:LE

Produced in:

U.S.

Research use:

Aging, Behavior, Diet induced obesity, Diet/Obesity, General studies, Metabolism, Nutrition

Strain:

HsdSage:LE-Lrrk1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk1/Lrrk2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Neuronal apoptosis

Strain:

HsdSage:SD-Mdr1a^em1Sage

Produced in:

U.S.

Research use:

ADMET, Pharmacology, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^em1SageMdr1b^em1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^em1SageAbcg2^em1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mecp2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

Strain:

HsdSage:SD-Met^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

Strain:

HsdSage:SD-Grm5^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

Strain:

HsdSage:SD-Abcc1a^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

Strain:

HsdSage:SD-Abcc2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

Strain:

Hsd:ND4

Produced in:

U.S.

Research use:

General studies, Infectious disease, Reproductive, Retinal ischemia research, Pain and neuroscience, Toxicology

Strain:

HsdSage:SD-Nrxn1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

Strain:

HsdSage:SD-Nlgn3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

Strain:

HsdHra:(NZW) SPF, Hsdlf:NZW

Produced in:

U.S., U.K.

Research use:

Antibody production, Atherosclerosis, Behavioral and learning disabilities, Biomedical research, Cardiovascular, Dermatology, General studies, Immunology, Oncology, Ophthalmology, Osteology, Pharmacology, Surgical, Teratology, Toxicology, Dermatology, Renal Studies

Strain:

NIH/OlaHsd

Produced in:

U.K.

Research use:

General purpose studies

Strain:

Hsd:NIHS

Produced in:

U.S., U.K.

Research use:

General studies

Strain:

HsdCpb:NMRI-Foxn1^nu, HsdCpb:NMRI-Foxn1^nu/Foxn1⁺

Produced in:

The Netherlands

Research use:

Oncology, Tumor growth, Antibody production, Autoimmune disease, Immunology, Transplantation

Strain:

HsdWin:NMRI

Produced in:

The Netherlands

Research use:

General studies, Immunology, Transplantation

Strain:

NOD.CB17-Prkdc^scid/NCrHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth

Strain:

Hsd:NSA(CF-1^®)

Produced in:

U.S.

Research use:

General studies, Surgical, Infectious disease, Toxicology

Strain:

HsdSage:SD-Slc22a6^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a8^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Drug transporter, ADMET, Drug-drug interactions, Drug metabolism, Hepatotoxicity

Strain:

HsdSage:SD-Oprm1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Addiction, Analgesia, Neuroscience, Nociception, Pain

Strain:

HsdSage:SD-Tp53^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

Strain:

HsdSage:SD-Ngfr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

Strain:

HsdSage:LE-Park2^em1Sage

Produced in:

U.S.

Research use:

Metabolism, Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Park7^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Pvalb^{em1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-Pink1^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Strain:

HsdSage:LE-Pink1^em1SagePark2^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Strain:

HsdSage:SD-Ppara^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

Strain:

HsdSage:SD-Prkdc^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

Strain:

HsdSage:SD-Pten^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cancer, Neuroscience, Oncology

Strain:

HsdSage:SD-Nr1i2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-Nr1i2^em1SageNr1i3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-NR1i2/NR1i3/AHR^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

F344-Rag1^em1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

Strain:

HsdSage:SD-Rag1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Oncology, Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

F344-Rag2^em1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rag2^em1sage

Produced in:

U.S.

Research use:

Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

Strain:

B6;129-Rag2^tm1FwaII2rg^tm1Rsky/DwlHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Imaging, Immunology, Immunotherapy, Neuropathology, Oncology, Stem cells, Tumor biology, Tumor growth, Cancer cell transplantation, Infectious disease

Strain:

HsdSage:SD-Rbfox1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neurodegenerative Disorders, Neuroscience

Strain:

M. mulatta

Produced in:

U.S.

Research use:

COVID-19, Diabetes, General studies, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology, Transplantation

Strain:

SAMP8/TaHsd, SAMR1/TaHsd (control)

Produced in:

The Netherlands

Research use:

Accelerated senescence studies, Age-dependent disorders, Brain atrophy, Deficits in learning and memory, Emotional disorders Aging process, Geriatric pathogenesis, Hearing impairment, Hyperinflation of the lungs, Senile amyloidosis (apolipoprotein A-II), Senile osteoporosis

Strain:

C.B-17/IcrHan^®Hsd-Prkdc^scid, C.B-17/IcrHsd-Prkdc^scid

Produced in:

U.S., U.K., The Netherlands, France

Research use:

General studies, Imaging, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth

Strain:

C.B-17/IcrHsd-Prkdc^scidLyst^bg-J

Produced in:

U.S., The Netherlands

Research use:

Gene therapy, General studies, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth, Teratology

Strain:

NOD.Cg-Prkdc^scidHr^hr/NCrHsd

Produced in:

Italy Cryopreserved

Research use:

Oncology, Humanization applications, Imaging applications, Xenograft transplantation

Strain:

SJL/JCrHsd

Produced in:

U.S.

Research use:

Behavior, Immunology

Strain:

SHR/NHsd

Produced in:

U.S.

Research use:

Hypertension, Surgical, Insulin resistant

Strain:

Hsd:Sprague Dawley^® SD^® Aged

Produced in:

U.S.

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

Hsd:Sprague Dawley^® SD^®

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Cardiovascular, COVID-19, Diabetes induced obesity, Diet induced obesity, General studies, Immunology, Infectious disease, Metabolism, Neurology, Neuroscience, Nutrition, Oncology, Preclinical (PK/PD), Reproductive, Surgical, Teratology, Toxicology, Tumor biology

Strain:

HsdSage: LE-SSt.Cre^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Tbx21^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Rosa26^{em1(tdTomato)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

Strain:

HsdOla:TO

Produced in:

U.K.

Research use:

General purpose

Strain:

HsdSage:LE-Tph2^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Parkinson's disease, Cre Tool for conditional expression or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Trpv1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Strain:

HsdSage:SD-TH^{em1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:LE-VGAT^{em1(IRES-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-VIP^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

WF/NHsd

Produced in:

U.S. Cryopreserved

Research use:

Oncology, Immunology, Leukemia, Transplantation

Strain:

RccHan^®:WIST

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, General studies, Nutrition, Oncology, Preclinical (PK/PD), Surgical, Teratology, Toxicology

Strain:

WKY/NHsd

Produced in:

U.S., U.K.

Research use:

Immunology, Inbred, normotensive control for SHR rat

Strain:

Hsd:WI

Produced in:

U.S.

Research use:

General studies, Aging, Nutrition, Oncology, Teratology

Strain:

HsdCpb:WU

Produced in:

U.K.

Research use:

Aging, General purpose model, Nutrition, Oncology, Teratology

Strain:

HsdHlr:ZUCKER-Lepr^fa, HsdHlr:ZUCKER-Lepr^fa/Lepr⁺-(Lean), HsdHlr:ZUCKER-Lepr⁺-(Lean)

Produced in:

U.S.

Research use:

Cardiovascular, Diabetes type 2, General studies, Obesity, Surgical