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Order code: 043
- Coat: Black
- Haplotype: H-2b
- High preference for alcohol
- Incidence of hydrocephalous
- Low tumor incidence
- Microphthalmia
- Most widely-used inbred strain
- The C57BL/6JRccHsd subline does not carry the Nnt (nicotinamide nucleotice transhydrogenase) gene deletion
Common age-associated conditions include:
- Hair loss
- Loss of motor skills and sensory perception
- Presence of spontaneous tumors
- Reduced immunologic and physiologic function
- Loss of vision, e.g. retinal degeneration, development of cataracts
Origin:
The C57BL/JRccHsd mice originate from Jackson Laboratory, Bar Harbor, Maine and were moved in 1973 to RCC Ltd. (formerly Ibm and BRL) in Füllinsdorf, Switzerland. To Harlan Laboratories through acquisition in 2004. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021.
Diet and Husbandry:
Our rodent models are raised and maintained on Teklad diet, bedding, and enrichment products:
- Diet: Teklad Global Rodent Diet
- Bedding: Teklad Contact Bedding (U.S. only)
- Enrichment: Teklad Enrichment Products (U.S. only)
Model Support Services:
Inotiv offers related model support services to deliver research-ready models to your facility:
![](https://www.inotiv.com/hs-fs/hubfs/resources/model-images/C57BL-6.png?width=400&name=C57BL-6.png)
Available regions:
Asia-Pacific
Austria
Baltic states
Belgium
East Europe
France
Germany
Ireland
Italy
Portugal
Scandinavia
Spain
Switzerland
The Netherlands
United States
United Kingdom
Other regions
For pricing information, please contact us using the phone number above.
![](https://www.inotiv.com/hs-fs/hubfs/resources/model-images/C57BL-6.png?width=400&name=C57BL-6.png)
Research use and related publications
- Age-associated pathology
- Cardiovascular
- Immune response
- Longevity
- Memory
- Metabolism
- Motor skills
- Osteoarthritis
- Neoplasia
- Neurobiology
- Renal degeneration
- Reproductive senescence
- Vision and hearing