Discovery Through Approval

Expect More—More Attention, More Insight, and a Superlative Experience

To succeed in discovery and development, you need high-quality data and painstaking interpretation to answer the right questions at the right time. As your discovery and development partner, Inotiv delivers both—along with a broad array of models, services and expertise to exceed your expectations. From research and discovery through nonclinical and clinical development stages, we steer you past regulatory pitfalls and equip you with strategic insights so you make informed decisions sooner.

Take advantage of our comprehensive services offering, long and impeccable regulatory history, world-class team of scientists, and track record of providing attentive, decisive support. For your critical work, expect more attention, more insight, and a superlative experience as we deliver the right-size solutions essential to your success.

Discovery Lead Selection Lead Optimization Preclinical Development Clinical Development I II III

Computational Tox/Toxicogenomics

In Silico Chemical Structure Evaluation/QSAR, PBPK Modeling, Gene Expression Profiling

IVIVE Modeling, Gene Expression Profiling

Pharmacology

In Vivo Efficacy Models, Rodent Telemetry

Targeted Proteomics, Disease Biomarkers, PK/PD Modeling

Drug Metabolism

Metabolic Stability, Metabolic Soft-Spots, Discovery PK Screening, Cell and Molecular Biology

In Vitro DDI (CYP and Transporters), Metabolite ID, PK/TK Analysis

DDI, Circulating Human Metabolites (MIST), PK Modeling

Safety Pharmacology

Exploratory Screening Using Large and Small Animal CNS, CV, Respiratory

Large Animal CV, Large and Small Animal Respiratory, Small Animal CNS

Toxicology

In Vitro Toxicology, Exploratory Toxicology (MTD/DRF)

IND Enabling Rodent/Non-Rodent

Sub Chronic and Chronic Toxicology

Carcinogenicity (Including Transgenic Mouse)

Genetic Toxicology

Screening, Mini Ames and In Vitro Micronucleus

Ames, In Vitro Cytogenetics, In Vivo MN/Comet

Bioanalysis

Exposure Analysis, Dose Formulation Analysis, Discovery Biotherapeutics and Biomarkers

Regulated Preclinical, Immunogenicity, Biomarkers

Regulated Bioanalysis, Biomarkers

Histology/Pathology

Target Tissue Assessment, Immunohistochemistry, Digital Imaging, Clinical Pathology

Histology and Pathology, Clinical Pathology

DART

Fertility and Early Embryonic Development

Embryo-Fetal Development

Pre and Postnatal Development

Research Models and Services

General Purpose Models, GEMS Models, Model Support Services

Teklad Diets

Standard Diets, Custom Diets, Bedding and Enrichment

Discovery and Translational Sciences Discovery and Translational Sciences From discovery pharmacology and toxicology, through regulated enabling safety assessment studies, our team has the in vivo and analytical capabilities to deliver a variety of flexible solutions adaptable to your needs.

Safety Assessment Safety Assessment Our nonclinical testing services feature veterinary surgeons, state-of-the-art imaging, and a commitment to excellence to advance your medical device.

research-models

Research Models and Services Research Models and Services Paired with the most comprehensive range of research models in the industry, we offer the experience, animal welfare, quality, and consistency that is essential to your success.

Teklad Diet and Bedding Teklad Diet and Bedding What comes out of your research depends in large part on what goes into your research models. Ensuring models have the most appropriate laboratory animal diet, bedding, and enrichment is critical to maintaining consistent, reliable data.