Surgical Models and Services

Keep your focus on designing, executing, and analyzing data from critical research studies while we handle the complex surgical model work.

Our animal surgical services personnel undergo rigorous training and evaluation prior to performing surgery, and surgical skills are continuously monitored. We utilize catheters in various surgical procedures to facilitate vascular access and ensure precise drug administration. Vascular catheterization is crucial in preclinical research for effective blood and fluid sampling and therapeutic dosing.

Inotiv offers cost-effective solutions to save you time and resources with:

High-quality surgically-modified models
Availability at convenient locations to reduce transit time
Access to surgical experts for model development and technical trouble shooting
Offers flexibility and a consultative approach
Innovative software system to track and monitor surgical model development

We also emphasize the importance of infusion techniques for the long-term delivery of medications and fluids during surgical procedures.

Inotiv also performs customer-specific surgical procedures on laboratory animals. For more information or pricing, please contact us to discuss your specific needs.

Inotiv is dedicated to providing the highest quality surgically modified rodent and large animal models with a focus on mouse and rat surgical services. Surgery personnel undergo rigorous training and evaluation prior to performing surgery. Surgical skills are continuously monitored. Our surgeons regularly receive outside educational training to improve their skills and increase their surgical knowledge. This includes detailed procedural instructions for performing carotid artery catheterization, emphasizing the careful dissection of surrounding muscles and the need to isolate the artery while taking precautions to avoid damaging the vagus nerve. Jugular vein catheterization is highlighted as a beneficial technique for preclinical research, enabling easy and repeated intravenous access without anesthesia. The technical process of catheterizing the left carotid artery is emphasized, highlighting surgical techniques for isolating and manipulating the artery to insert a catheter safely.

Learn more about surgical models with their related publications.

Inotiv is dedicated to the humane care and use of research animals. All surgical modifications are reviewed and approved in advance by Inotiv’s Institutional Animal Care and Use Committee (IACUC). Inotiv’s veterinarians provide oversight and technical and professional support to surgical personnel.

All surgical procedures are performed by trained and tested surgeons using aseptic technique in surgical facilities dedicated to maximum-security production barriers or isolators. Surgically-modified models are monitored postoperatively to ensure complete recovery from surgery. All animals undergoing major survival surgery (as defined by the Guide for the Care and Use of Laboratory Animals, 2011) receive post-operative analgesia to further ensure their humane and ethical care. Exceptions to analgesic requirements will require pre-approval by Inotiv’s IACUC.

Inotiv recognizes the need to supplement enrichment to those animals needing to be singly housed after surgery (e.g., catheterized rats). Therefore, we provide these animals with a section of inert nylabone for gnawing or provide supplemental novel material for bedding. These enrichment items are provided to animals immediately post operatively and remain with them until delivery to the client.

Surgical Models and Services

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