From our comprehensive online resources, through to our model selection consultants and study directors — talk to us about your oncology portfolio needs from start to finish.
Visit our cell line references page to find proven Inotiv models with extensive references. Read our cell line posts.
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Rodent models for oncology research
Inotiv provides high-quality nude mice, SCID mice, and nude rats with proven performance in tumor uptake and growth. No matter where you are, valid research depends on the stability and consistency of your models. Hidden ingredients in your models’ diets can negatively impact oncology research, so we raise our animals on Teklad diets which are free of ingredients that could reduce the reliability of your research results.
Genetically engineered models (GEMs)
Inotiv offers a large collection of pre-developed genetically engineered oncology rat models including advanced disease research rat models including tumor suppressor genes and oncogene models to name a few. Inotiv is a leader in molecular and phenotypic services featuring extensive scientific expertise in customized study and assay design, numerous in life and end point measurements, and study flexibility with comprehensive scientific project management.
We are consistently and reliably available to partner with you on a scientific and personal level to design, execute, and deliver exactly what you need to achieve and exceed your research and development goals.
| RAT MODEL | SPECIFIC DISEASE/BIOLOGICAL FUNCTION | THERAPEUTIC AREA |
|---|---|---|
| Lgals1 (Gal1) KO | RA, Crohn’s disease, Colitis | Immunology, Oncology |
| p53 KO | Oncology | Oncology |
| Prkdc KO | Immunology | Immunology, Oncology |
| Pten KO | Autism (ASD), Oncology | Neuroscience, Oncology |
| Rag1 KO (F344) Rag1 KO (SD) Rag2 KO (F344) Rag2 KO (SD) |
Immunology | Immunology, Oncology |
| Tbx21 (T-beta) KO | RA, Crohn’s disease, Colitis | Immunology, Oncology |
Cell line reference tool
Leveraging our up-to-date online reference tool, we will work with you to choose the most appropriate animal models for your oncology research. Inotiv’s extensive online database of peer-reviewed publications across major cancer cell lines enables you to choose the best models. Now you can make more confident, time-efficient model selections. Read our cell line posts.
Tumor growth data
You need established tumor growth rates to help you secure the most appropriate models. Our online library of in vivo tumor growth data provides your researchers with representative tumor growth curves for tumor cell lines and xenograft models of interest. Our tumor growth data sheets cover a variety of tissue types, cell lines, and xenograft models to assist you in making the best decisions.
Teklad Global Rodent Diets® for oncology
Did you know that phytoestrogens, chlorophyll, and nitrosamines can adversely affect your studies? That is why we have removed undesirable compounds from teklad diets so you can be confident that your research isn’t being impacted by unwanted ingredients.
Oncology research services
Inotiv offers a number of services to support your oncology research.
Gene expression services — Advanced throughput technologies customized to meet your research needs.
Monoclonal antibody production services — You can rely on our 25+ years of experience with in vivo and in vitro mAb production for various global research applications.
Contract breeding — Laboratory operations in Europe offer contract breeding of oncology models to guarantee your supply of appropriate models.
PDX models — We offer highly characterized Patient-Derived Xenograft (PDX) models for breast cancer and melanoma.
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