CD-1 Nude Mice
[General Studies] Gamage TH, Gunnes G, Lee RH, Louch WE, Holmgren A, Bruton JD, Lengle E, Kolstad TRS, Revold T, Amundsen SS, Dalen KT, Holme PA, Tjønnfjord GE, Christensen G, Westerblad H, Klungland A, Bergmeier W, Misceo D, Frengen E., STIM1 R304W causes muscle degeneration and impaired platelet activation in mice, Cell Calcium. 2018 Dec;76:87-100. doi: 10.1016/j.ceca.2018.10.001. Epub 2018 Oct 5.
[Oncology] Andersen CL, Liu M, Wang Z, Ye X, Xiao S., Chemotherapeutic agent doxorubicin alters uterine gene expression in response to estrogen in ovariectomized CD-1 adult mice†, Biol Reprod. 2019 Apr 1;100(4):869-871. doi: 10.1093/biolre/ioy259.
Non-Swiss Albino Outbred Mice
[General Studies] Logsdon DM, Ermisch AF, Kile R, Schoolcraft WB, Krisher RL, Yuan Y., Egg cylinder development during in vitro extended embryo culture predicts the post transfer developmental potential of mouse blastocysts, J Assist Reprod Genet. 2020 Apr;37(4):747-752. doi: 10.1007/s10815-020-01714-9. Epub 2020 Feb 18.
New Zealand White Rabbits
[Toxicology] Lawrence WS, Peel JE, Sivasubramani SK, Baze WB, Whorton EB, Beasley DWC, Comer JE, Hughes DE, Ling LL, Peterson JW., Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model, Pathogens. 2020 Sep 22;9(9):773. doi: 10.3390/pathogens9090773.
Spontaneously Hypertensive Inbred Rats
[Hypertension] Pokrzywinski KL, Biel TG, Rosen ET, Bonanno JL, Aryal B, Mascia F, Moshkelani D, Mog S, Rao VA., Doxorubicin-induced cardiotoxicity is suppressed by estrous-staged treatment and exogenous 17β-estradiol in female tumor-bearing spontaneously hypertensive rats, Biol Sex Differ. 2018 Jun 15;9(1):25. doi: 10.1186/s13293-018-0183-9.
Sprague Dawley® Outbred Rats
[Aging] Cao S, Wastney ME, Lachcik PJ, Xiao HH, Weaver CM, Wong MS., Both Oleanolic Acid and a Mixture of Oleanolic and Ursolic Acids Mimic the Effects of Fructus ligustri lucidi on Bone Properties and Circulating 1,25-Dihydroxycholecalciferol in Ovariectomized Rats, J Nutr. 2018 Dec 1;148(12):1895-1902. doi: 10.1093/jn/nxy242.
[Aging] Mackert GA, Schulte M, Hirche C, Kotsougiani D, Vogelpohl J, Hoener B, Fiebig T, Kirschner S, Brockmann MA, Lehnhardt M, Kneser U, Harhaus L. Low-energy extracorporeal shockwave therapy (ESWT) improves metaphyseal fracture healing in an osteoporotic rat model, PLoS One. 2017 Dec 12;12(12):e0189356. doi: 10.1371/journal.pone.0189356. eCollection 2017.
[Cardiovascular] Cruz MV, Luker JN, Carney BC, Brummel-Ziedins KE, Bravo MC, Orfeo T, Chen JH, Moffatt LT, Shupp JW. Reference ranges for rotational thromboelastometry in male Sprague Dawley rats, Thromb J. 2017 Dec 28;15:31. doi: 10.1186/s12959-017-0154-0. eCollection 2017.
[General Studies] Bakewell SJ, Carie A, Costich TL, Sethuraman J, Semple JE, Sullivan B, Martinez GV, Dominguez-Viqueira W, Sill KN., Imaging the delivery of drug-loaded, iron-stabilized micelles, Nanomedicine. 2017 May;13(4):1353-1362. doi: 10.1016/j.nano.2017.01.009. Epub 2017 Jan 20.
[General Studies] Sharma PK, Avula B, Panda A, Wang YH, Khan IA, Murthy SN., A sensitive bioanalytical method for quantitative determination of resiniferatoxin in rat plasma using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and its application in pharmacokinetic study, J Pharm Biomed Anal. 2019 Feb 20;165:284-291. doi: 10.1016/j.jpba.2018.12.024. Epub 2018 Dec 14.
[General Studies] Vigiola Cruz M, Carney BC, Luker JN, Monger KW, Vazquez JS, Moffatt LT, Johnson LS, Shupp JW., Plasma Ameliorates Endothelial Dysfunction in Burn Injury,J Surg Res. 2019 Jan;233:459-466. doi: 10.1016/j.jss.2018.08.027. Epub 2018 Sep 22.
[General Studies] Cao J, Ng M, Felmlee MA., Sex Hormones Regulate Rat Hepatic Monocarboxylate Transporter Expression and Membrane Trafficking, J Pharm Pharm Sci. 2017;20(1):435-444. doi: 10.18433/J3CH29.
[General Studies] Shao XM, Liu S, Lee ES, Fung D, Pei H, Liang J, Mudgway R, Zhang J, Feldman JL, Zhu Y, Louie S, Xie XS. Chronic intermittent nicotine delivery via lung alveolar region-targeted aerosol technology produces circadian pharmacokinetics in rats resembling human smokers, J Appl Physiol (1985). 2018 Nov 1;125(5):1555-1562. doi: 10.1152/japplphysiol.00357.2018. Epub 2018 Sep 20.
[General Studies] Hill K, Walker SN, Salminen A, Chung HL, Li X, Ezzat B, Miller JJ, DesOrmeaux JS, Zhang J, Hayden A, Burgin T, Piraino L, May MN, Gaborski TR, Roussie JA, Taylor J, DiVincenti L Jr, Shestopalov AA, McGrath JL, Johnson DG. Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis, Adv Healthc Mater. 2020 Feb;9(4):e1900750. doi: 10.1002/adhm.201900750. Epub 2020 Jan 15.
[Immunology] Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, Wen L, Husain SZ, Sugar CA, Roos J, Ramos S, Lugea A, Dunn M, Stauderman K, Pandol SJ., The Orai Ca(2+) channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis, J Physiol. 2019 Jun;597(12):3085-3105. doi: 10.1113/JP277856. Epub 2019 May 22.
[Neuroscience] Huijgens PT, Snoeren EMS, Meisel RL, Mermelstein PG., Effects of gonadectomy and dihydrotestosterone on neuronal plasticity in motivation and reward related brain regions in the male rat, J Neuroendocrinol. 2021 Jan;33(1):e12918. doi: 10.1111/jne.12918. Epub 2020 Dec 19.
[Neuroscience] Dantzler HA, Kline DD., Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia, Auton Neurosci. 2020 Dec;229:102735. doi: 10.1016/j.autneu.2020.102735. Epub 2020 Sep 28.
[Neuroscience] Ji Y, Hu B, Klontz C, Li J, Dessem D, Dorsey SG, Traub RJ., Peripheral mechanisms contribute to comorbid visceral hypersensitivity induced by preexisting orofacial pain and stress in female rats, Neurogastroenterol Motil. 2020 Jul;32(7):e13833. doi: 10.1111/nmo.13833. Epub 2020 Mar 10.
[Neuroscience] Kao HW, Lin YY, Gwathney WJ, Hong K., Formulation and evaluation of multilamellar vesicles ropivacaine in pain management, Int J Nanomedicine. 2019 Sep 27;14:7891-7901. doi: 10.2147/IJN.S215952. eCollection 2019.
[Neuroscience] Wright DM, Small KM, Nag S, Mokha SS., Activation of Membrane Estrogen Receptors Attenuates NOP-Mediated Tactile Antihypersensitivity in a Rodent Model of Neuropathic Pain, Brain Sci. 2019 Jun 21;9(6):147. doi: 10.3390/brainsci9060147.
[Neuroscience] Hay M, Polt R, Heien ML, Vanderah TW, Largent-Milnes TM, Rodgers K, Falk T, Bartlett MJ, Doyle KP, Konhilas JP., A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction, J Pharmacol Exp Ther. 2019 Apr;369(1):9-25. doi: 10.1124/jpet.118.254854. Epub 2019 Feb 1.
[Neuroscience] Gross KS, Moore KM, Meisel RL, Mermelstein PG., mGluR5 Mediates Dihydrotestosterone-Induced Nucleus Accumbens Structural Plasticity, but Not Conditioned Reward, Front Neurosci. 2018 Nov 20;12:855. doi: 10.3389/fnins.2018.00855. eCollection 2018.
[Neuroscience] Sanna F, Bratzu J, Piludu MA, Corda MG, Melis MR, Giorgi O, Argiolas A., Dopamine, Noradrenaline and Differences in Sexual Behavior between Roman High and Low Avoidance Male Rats: A Microdialysis Study in the Medial Prefrontal Cortex, Front Behav Neurosci. 2017 Jun 7;11:108. doi: 10.3389/fnbeh.2017.00108. eCollection 2017.
[Neuroscience] Benmansour S, Arroyo LD, Frazer A., Comparison of the Antidepressant-Like Effects of Estradiol and That of Selective Serotonin Reuptake Inhibitors in Middle-Aged Ovariectomized Rats, Front Aging Neurosci. 2016 Dec 21;8:311. doi: 10.3389/fnagi.2016.00311. eCollection 2016.
[Neuroscience] Martinez LA, Gross KS, Himmler BT, Emmitt NL, Peterson BM, Zlebnik NE, Foster Olive M, Carroll ME, Meisel RL, Mermelstein PG. Estradiol Facilitation of Cocaine Self-Administration in Female Rats Requires Activation of mGluR5, eNeuro. 2016 Oct 25;3(5):ENEURO.0140-16.2016. doi: 10.1523/ENEURO.0140-16.2016. eCollection 2016 Sep-Oct.
[Neuroscience] Robinson DL Jr, Nag S, Mokha SS. Estrogen facilitates and the kappa and mu opioid receptors mediate antinociception produced by intrathecal (-)-pentazocine in female rats, Behav Brain Res. 2016 Oct 1;312:163-8. doi: 10.1016/j.bbr.2016.06.019. Epub 2016 Jun 14.
[Neuroscience] Radford KD, Park TY, Jaiswal S, Pan H, Knutsen A, Zhang M, Driscoll M, Osborne-Smith LA, Dardzinski BJ, Choi KH. Enhanced fear memories and brain glucose metabolism (18F-FDG-PET) following sub-anesthetic intravenous ketamine infusion in Sprague-Dawley rats, Transl Psychiatry. 2018 Nov 30;8(1):263. doi: 10.1038/s41398-018-0310-8.
[Nutrition] Cladis DP, Debelo H, Lachcik PJ, Ferruzzi MG, Weaver CM., Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats, Mol Nutr Food Res. 2020 Jun;64(12):e2000031. doi: 10.1002/mnfr.202000031. Epub 2020 May 27.
[Oncology] Sharp AM, Lertphinyowong S, Yee SS, Paredes D, Gelfond J, Johnson-Pais TL, Leach RJ, Liss M, Risinger AL, Sullivan AC, Thompson IM, Morilak DA., Vortioxetine reverses medial prefrontal cortex-mediated cognitive deficits in male rats induced by castration as a model of androgen deprivation therapy for prostate cancer, Psychopharmacology (Berl). 2019 Nov;236(11):3183-3195. doi: 10.1007/s00213-019-05274-4. Epub 2019 May 28.
[Preclincial (PK/PD)] Kim YJ, Tu Y, Chow DS., Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats, J Pharm Biomed Anal. 2018 Nov 30;161:122-128. doi: 10.1016/j.jpba.2018.07.058. Epub 2018 Aug 2.
[Preclincial (PK/PD)] Rioux N, Smith S, Korpal M, O'Shea M, Prajapati S, Zheng GZ, Warmuth M, Smith PG., Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA), Cancer Chemother Pharmacol. 2019 Jan;83(1):151-160. doi: 10.1007/s00280-018-3716-3. Epub 2018 Nov 1.
[Preclincial (PK/PD)] Grecco GG, Kisor DF, Sprague JE., Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats, Data Brief. 2018 Oct 25;21:1045-1050. doi: 10.1016/j.dib.2018.10.073. eCollection 2018 Dec.
[Preclincial (PK/PD)] Sarkar M, Grossman RG, Toups EG, Chow DS., Rational design and development of a stable liquid formulation of riluzole and its pharmacokinetic evaluation after oral and IV administrations in rats, J Surg Res. 2019 Jan;233:459-466. doi: 10.1016/j.jss.2018.08.027. Epub 2018 Sep 22.
[Preclincial (PK/PD)] Katyayan KK, Hui YH. An evaluation of metabolite profiling of six drugs using dried blood spot, Xenobiotica. 2019 Dec;49(12):1458-1469. doi: 10.1080/00498254.2019.1572938. Epub 2019 Feb 18.
[Toxicology] Cladis DP, Li S, Reddivari L, Cox A, Ferruzzi MG, Weaver CM., A 90 day oral toxicity study of blueberry polyphenols in ovariectomized sprague-dawley rats, Food Chem Toxicol. 2020 May;139:111254. doi: 10.1016/j.fct.2020.111254. Epub 2020 Mar 9.
[Toxicology] Huang MC, Dzierlenga AL, Robinson VG, Waidyanatha S, DeVito MJ, Eifrid MA, Granville CA, Gibbs ST, Blystone CR. Toxicokinetics of perfluorobutane sulfonate (PFBS), perfluorohexane-1-sulphonic acid (PFHxS), and perfluorooctane sulfonic acid (PFOS) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration, Toxicol Rep. 2019 Jun 28;6:645-655. doi: 10.1016/j.toxrep.2019.06.016. eCollection 2019.
[Toxicology] Huang MC, Robinson VG, Waidyanatha S, Dzierlenga AL, DeVito MJ, Eifrid MA, Gibbs ST, Blystone CR., Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration, Toxicol Rep. 2019 Aug 20;6:924-932. doi: 10.1016/j.toxrep.2019.08.009. eCollection 2019.
[Toxicology] Leber A, Hontecillas R, Zoccoli-Rodriguez V, Ehrich M, Chauhan J, Bassaganya-Riera J., Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1, Drug Chem Toxicol. 2019 Oct 25:1-6. doi: 10.1080/01480545.2019.1679828. Online ahead of print.
[Toxicology] Roberts SM, Rohr AC, Mikheev VB, Munson J, Sabo-Attwood T., Influence of airborne particulates on respiratory tract deposition of inhaled toluene and naphthalene in the rat, Inhal Toxicol. 2018 Jan;30(1):19-28. doi: 10.1080/08958378.2018.1438539. Epub 2018 Feb 21.
[Toxicology] Waidyanatha S, Black SR, Patel PR, Watson SL, Snyder RW, Sutherland V, Stanko J, Fennell TR, Disposition and metabolism of antibacterial agent, triclocarban, in rodents; a species and route comparison, Xenobiotica. 2020 December ; 50(12): 1469–1482. doi:10.1080/00498254.2020.1779391
[Toxicology] Waidyanatha S, McDonald JD, Sanders JM, Doyle-Eisele M, Moeller BC, Garner CE., Disposition and metabolism of 2,2'-dimorpholinodiethyl ether in sprague dawley rats and B6C3F1/N mice after oral, intravenous administration, and dermal application, Xenobiotica. 2020 Nov;50(11):1341-1351. doi: 10.1080/00498254.2020.1779389. Epub 2020 Jun 22.
[Toxicology] Zhang N, Sarkar AK, Li F, Demerzhan SA, Gilbertson SR, Pati D., Stability and pharmacokinetics of separase inhibitor-Sepin-1 in Sprague-Dawley rats, Biochem Pharmacol. 2020 Apr;174:113808. doi: 10.1016/j.bcp.2020.113808. Epub 2020 Jan 10.
[Toxicology] Zhang N, Sarkar AK, Pati D. Data set on Separase Inhibitor-Sepin-1 toxicity on organ weights, hematology and clinical parameters in Sprague-Dawley rats, Data Brief. 2020 Jan 22;29:105159. doi: 10.1016/j.dib.2020.105159. eCollection 2020 Apr.
Wistar Han® Outbred Rats
[Preclincial (PK/PD)] Ravula A, Chandasana H, Jagnarine D, Wall SC, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats, Cannabis Cannabinoid Res. 2019 Dec 6;4(4):240-254. doi: 10.1089/can.2019.0049. eCollection 2019.
[Preclincial (PK/PD)] Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant, J Pharm Biomed Anal. 2018 Oct 25;160:119-125. doi: 10.1016/j.jpba.2018.07.004. Epub 2018 Jul 19.
Zucker Obese Rats
[Cardiovascular] Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC. Protection from vascular dysfunction in female rats with chronic stress and depressive symptoms. Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1070-H1084. doi: 10.1152/ajpheart.00647.2017. Epub 2018 Feb 16.
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