Lrrk1 knockout rats: HsdSage:LE-Lrrk1em1Sage GEM rats

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Cryopreserved

Typically heterozygous rats are cryo-recovered in 10-12 weeks to an age of 7 weeks old. Subsequently homozygous rats to an age of 7 weeks old can be produced within 20-22 weeks.

Background strain: Long Evans Hooded

Availability: Cryopreserved as heterozygous embryos
Zygosity: Heterozygous as live colony

Developed in collaboration with The Michael J. Fox Foundation, this model contains a deletion of the Lrrk1 gene, encoding for the leucine-rich repeat kinase 1. This model is useful in understanding Lrrk1 biology.

Origin: The Lrrk1 KO rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo, then Envigo was acquired by Inotiv in 2021.

Available regions:

Asia-Pacific Austria Baltic states Belgium East Europe France Germany Ireland Italy Portugal Scandinavia Spain Switzerland The Netherlands United States United Kingdom Other regions

For pricing please contact us using the phone number above