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hApoE4 knockin rats
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Alzheimer's disease
Cardiovascular
Neuroscience
Alzheimer's disease
Kulkarni P, Grant S, Morrison TR, Cai X, Iriah S, Kristal BS, Honeycutt J, Brenhouse H, Hartner JC, Madularu D, Ferris CF.,
Characterizing the human APOE epsilon 4 knock-in transgene in female and male rats with multimodal magnetic resonance imaging,
Brain Res. 2020 Nov 15;1747:147030. doi: 10.1016/j.brainres.2020.147030. Epub 2020 Jul 31.
Emam S, Nasrollahpour M, Colarusso B, Cai X, Grant S, Kulkarni P, Ekenseair A, Gharagouzloo C, Ferris CF, Sun NX.,
Detection of presymptomatic Alzheimer's disease through breath biomarkers,
Alzheimers Dement (Amst). 2020 Oct 14;12(1):e12088. doi: 10.1002/dad2.12088. eCollection 2020.
Cardiovascular
Wu, Y., Johnson, G., Zhao, F., Wu, Y., Zhao, G., Brown, A., You, S., Zou, M.H., Song, P. (2021),
Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models,
International Journal of Molecular Sciences, 22, 8262. doi:10.3390/ijms22158262.
Wu, Y.; Johnson, G.; Zhao, F.; Wu, Y.; Zhao, G.; Brown, A.; You, S.; Zou, M.-H.; Song, P.,
Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models,
International Journal of Molecular Sciences. 2021; 22(15):8262.
Wu Y, Zhao F, Sure V., et al.,
Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function,
Transl Psychiatry. 2022;12(1):119.
Wu Y, Zhao F, Sure VN, Ibrahim A, Yu C, Carr SM, Song P.,
Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function,
Cells. 2023 Jan 17;12(3):347. doi: 10.3390/cells12030347.
Neuroscience
Har-Paz, Ilona, Elor Arieli, and Anan Moran,
ApoE4 attenuates cortical neuronal activity in young behaving apoE4 rats,
Neurobiology of Disease 155 (2021): 105373
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