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Cntnap2 knockout rats
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Autism
Neuroscience
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Autism
Scott KE, Kazazian K, Mann RS, Möhrle D, Schormans AL, Schmid S, Allman BL.,
Loss of Cntnap2 in the Rat Causes Autism-Related Alterations in Social Interactions, Stereotypic Behavior, and Sensory Processing,
Autism Res. 2020 Oct;13(10):1698-1717. doi: 10.1002/aur.2364. Epub 2020 Sep 11.
Neuroscience
Scott KE, Schormans AL, Pacoli KY, De Oliveira C, Allman BL, Schmid S.,
Altered Auditory Processing, Filtering, and Reactivity in the Cntnap2 Knock-Out Rat Model for Neurodevelopmental Disorders.,
J Neurosci. 2018 Oct 3;38(40):8588-8604.
Dorit Möhrle, Megan Yuen, Alice Zheng, Faraj L. Haddad, Brian L. Allman, Susanne Schmid,
Characterizing maternal isolation-induced ultrasonic vocalizations in a gene–environment interaction rat model for autism,
Genes, brain, and behavior, 22(3), e12841. https://doi.org/10.1111/gbb.12841
Thomas AM, Schwartz MD, Saxe MD, Kilduff TS.,
Cntnap2 Knockout Rats and Mice Exhibit Epileptiform Activity and Abnormal Sleep-Wake Physiology.,
Sleep. 2017 Jan 1;40(1).
Mann RS, Allman BL, Schmid S.,
Developmental changes in electrophysiological properties of auditory cortical neurons in the Cntnap2 knockout rat.,
J Neurophysiol. 2023 Apr 1;129(4):937-947. doi: 10.1152/jn.00029.2022
Zheng A, Scott KE, Schormans AL, Mann R, Allman BL, Schmid S.,
Differences in Startle and Prepulse Inhibition in Contactin-associated Protein-like 2 Knock-out Rats are Associated with Sex-specific Alterations in Brainstem Neural Activity,
Neuroscience. 2023 Mar 1;513:96-110. doi: 10.1016/j.neuroscience.2023.01.020.
Scott KE, Mann RS, Schormans AL, Schmid S, Allman BL.,
Hyperexcitable and immature-like neuronal activity in the auditory cortex of adult rats lacking the language-linked CNTNAP2 gene,
Behav Brain Res. 2022;418:113642. doi:10.1016/j.bbr.2021.113642
Haddad FL, De Oliveira C, Schmid S.,
Investigating behavioral phenotypes related to autism spectrum disorder in a gene-environment interaction model of Cntnap2 deficiency and Poly I:C maternal immune activation.,
Front Neurosci. 2023 Mar 14;17:1160243. doi: 10.3389/fnins.2023.1160243. eCollection 2023.
Other
Mohrle, D., Wang, W., Whitehead, S., Schmid, S.,
GABAB Receptor Agonist R-Baclofen Reverses Altered Auditory Reactivity and Filtering in the Cntnap2 Knock-Out Rat,
Front. Integr. Neurosci., 20 August 2021.
Poulin, C. J., & Fox, A. E.,
Preliminary evidence for timing abnormalities in the CNTNAP2 knockout rat,
Behavioural Processes 190 (2021): 104449.
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