Inotiv offers a large collection of pre-developed genetically engineered ADME/Tox rat models including advanced disease research rat models including drug metabolism and transport and xenobiotic senor models to name a few. Inotiv is a leader in molecular and phenotypic services featuring extensive scientific expertise in customized study and assay design, numerous in life and end point measurements, and study flexibility with comprehensive scientific project management.
We are consistently and reliably available to partner with you on a scientific and personal level to design, execute, and deliver exactly what you need to achieve and exceed your research and development goals.
Rat Model | Specific Disease/Biological Function | Therapeutic Area |
---|---|---|
Bcrp KO BSEP KO CAR KO Mdr1a KO Mdr1a/1b KO Mdr1a-Bcrp KO Mrp1 KO Mrp2 KO Oat1 KO Oat3 KO Oct1 KO Oct2 KO |
Drug metabolism, Transporter | ADMET |
Ppara KO | Diabetes, Drug metabolism, Obesity, Xenobiotic | ADMET, Immunology |
PXR KO PXR/CAR KO PXR/CAR/AHR KO |
Drug metabolism, Xenobiotic | ADMET |
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