Exploratory Toxicology

In Vivo Pharmacokinetics (PK) and Acute Tolerability studies are critical components of any drug discovery program. Exploratory Toxicology data can contribute to more informed decision making when addressing the safety of a drug even when projects are in the drug discovery phase.

Without Exploratory Toxicology in the drug discovery phase, important safety considerations that could arise later in development may impact overall success. This can result in significant financial losses and setbacks in the drug development process.

At Inotiv, we recognize the importance of Exploratory Toxicology and how it is essential to work with a trusted partner to ensure that your drug candidates are being assessed appropriately. Inotiv offers a comprehensive suite of toxicology services to support drug discovery and development. Through scientific partnership with our clients, our team of experts work diligently to provide high-quality data and insights to ensure the safety and efficacy of new drug candidates.

Learn how efficiently your drug discovery program needs can be met by utilizing Inotiv’s expertise, including:

In Vivo Pharmacokinetics in multiple species
Rapid PK Screening Studies with quick data turn around
Definitive PK studies to enable understanding of clearance mechanisms and metabolism
Acute Tolerability Assessment to understand dose proportionality and acute toxicity
Exposure analysis by LC-MS/MS and PK/TK modeling included for a bundled solution

General Toxicology General Toxicology Inotiv offers a range of general toxicology studies to evaluate the safety of drugs, medical devices, and other chemicals. We design and conduct studies according to international regulations and our toxicology expertise can help assess potential risks and ensure the safety of your product.

Pathology Pathology Access world-class anatomical, clinical, and medical device pathology services, from routine histochemistry, IHC, IF, and ISH to stereology.

Surgical Models and Medical Device Testing Surgical Models and Medical Device Testing Our nonclinical testing services feature veterinary surgeons, state-of-the-art imaging, and a commitment to excellence to advance your medical device.

Drug Metabolism and Pharmacokinetics (DMPK) Drug Metabolism and Pharmacokinetics (DMPK) From discovery to regulatory-enabling safety assessments in advanced developmental and reproductive toxicology (DART), we have the in vivo services and associated bioanalysis capabilities you need to find answers.

Consulting Consulting Our experts deliver the insights you deserve to get the answers you need, whether in DMPK data analysis, biomarker analysis, or bioequivalence studies.

Bioanalysis Bioanalysis We offer customized end-to-end bioanalytical solutions to achieve your milestones effectively and on schedule, supporting the development of a wide range of therapeutics from discovery through Phase IV.

Learn how efficiently your drug discovery program needs can be met by utilizing Inotiv’s expertise, including:

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