C.B-17 SCID
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General studies
Chiu JE, Renard I, Pal AC, Singh P, Vydyam P, Thekkiniath J, Kumar M, Gihaz S, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Mamoun CB., Effective Therapy Targeting Cytochrome bc(1) Prevents Babesia Erythrocytic Development and Protects from Lethal Infection, Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0066221. doi: 10.1128/AAC.00662-21. Epub 2021 Aug 17.
Li, Fu; Ulrich, Michelle L; Shih, Vincent Feng-Sheng; Cochran, Julia H; Hunter, Joshua H; Westendorf, Lori; Neale, Jason; Benjamin, Dennis R;, Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-Fc?R Interaction, Molecular cancer therapeutics Vol.18, 2019
Imaging
Gill H, Seipert R, Carroll VM, Gouasmat A, Yin J, Ogasawara A, de Jong I, Phan MM, Wang X, Yang J, Ilovich O, Marik J, Williams SP, The Production, Quality Control, and Characterization of ZED8, a CD8-Specific, AAPS J. 2020 Jan 3;22(2):22.
Immunology
Liu, Z., Gunasekaran, K., Wang, W., Razinkov, V., Sekirov, L., Leng, E., . . . Yan, W. (2014)., Asymmetrical fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies., The Journal of Biological Chemistry, 289(6), 3571-3590. doi:10.1074/jbc.M113.513366 [doi]
Fang, R., Ismail, N., & Walker, D. H. (2012)., Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium., The American Journal of Pathology, 181(1), 185-195. doi:10.1016/j.ajpath.2012.03.020 [doi]
Wallach-Dayan, S. B., Elkayam, L., Golan-Gerstl, R., Konikov, J., Zisman, P., Dayan, M. R., . . . Breuer, R. (2015), Cutting edge: FasL(+) immune cells promote resolution of fibrosis., Journal of Autoimmunity, 59, 67-76. doi:10.1016/j.jaut.2015.02.006 [doi]
Chand M, Choi JY, Pal AC, Singh P, Kumari V, Thekkiniath J, Gagnon J, Timalsina S, Gaur G, Williams S, Ledizet M, Mamoun CB., Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti, Front Cell Infect Microbiol. 2022 Nov 25;12:1039197. doi: 10.3389/fcimb.2022.1039197. eCollection 2022.
Rogovskyy, A. S., Casselli, T., Tourand, Y., Jones, C. R., Owen, J. P., Mason, K. L., . . . Bankhead, T. (2015)., Evaluation of the importance of VlsE antigenic variation for the enzootic cycle of borrelia burgdorferi., PloS One, 10(4), e0124268. doi:10.1371/journal.pone.0124268 [doi]
Hossain, M., Qadri, S. M., & Liu, L. (2012)., Inhibition of nitric oxide synthesis enhances leukocyte rolling and adhesion in human microvasculature, Journal of Inflammation (London, England), 9(1), 28-9255-9-28. doi:10.1186/1476-9255-9-28 [doi]
Jones, R. J., Iempridee, T., Wang, X., Lee, H. C., Mertz, J. E., Kenney, S. C., . . . Orlowski, R. Z. (2016)., Lenalidomide, thalidomide, and pomalidomide reactivate the epstein-barr virus lytic cycle through phosphoinositide 3-kinase signaling and ikaros expression., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(19), 4901-4912. doi:1078-0432.CCR-15-2242 [pii]
Burette M, Allombert J, Lambou K, Maarifi G, Nisole S, Di Russo Case E, Blanchet FP, Hassen-Khodja C, Cabantous S, Samuel J, Martinez E, Bonazzi M., Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein, Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13708-13718. doi: 10.1073/pnas.1914892117. Epub 2020 Jun 1.
Case EDR, Mahapatra S, Hoffpauir CT, Konganti K, Hillhouse AE, Samuel JE, Van Schaik EJ., Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii, Microbiol Spectr. 2022 Aug 31;10(4):e0248421. doi: 10.1128/spectrum.02484-21. Epub 2022 Aug 1.
Gill, S., Vasey, A. E., De Souza, A., Baker, J., Smith, A. T., Kohrt, H. E., . . . Negrin, R. S. (2012)., Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells, Blood, 119(24), 5758-5768. doi:10.1182/blood-2012-03-415364 [doi]
Wintrob, Z. A., Oppong, E. K., Foster, M., Martorana, M., Tse, Y. C., Zhong, L., . . . Ceacareanu, A. C. (2014), Sexual dimorphism, weight gain and glucose intolerance in a B- and T-cell deficient mouse model., Cytokine, 67(2), 102-106. doi:10.1016/j.cyto.2014.02.011 [doi]
Manthey, Carl L; Moore, Beverley A; Chen, Yanqing; Loza, Matthew J; Yao, Xiang; Liu, Hao; Belkowski, Stanley M; Raymond-Parks, Holly; Dunford, Paul J; Leon, Francisco; Towne, Jennifer E; Plevy, Scott E;, The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis., PloS one Vol.14, 2019
Rosario, M., Liu, B., Kong, L., Collins, L. I., Schneider, S. E., Chen, X., . . . Fehniger, T. A. (2016)., The IL-15-based ALT-803 complex enhances FcgammaRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(3), 596-608. doi:10.1158/1078-0432.CCR-15-1419 [doi]
Felder, Mildred; Kapur, Arvinder; Rakhmilevich, Alexander L; Qu, Xiaoyi; Sondel, Paul M; Gillies, Stephen D; Connor, Joseph; Patankar, Manish S, UC16 suppresses human and murine innate immune responses., Gynecologic oncology Vol.152, 2019
Infectious disease
Pal AC, Renard I, Singh P, Vydyam P, Chiu JE, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Ben Mamoun C., Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo, J Infect Dis. 2022 Sep 28;226(7):1267-1275. doi: 10.1093/infdis/jiac181.
Chiu JE, Renard I, George S, Pal AC, Alday PH, Narasimhan S, Riscoe MK, Doggett JS, Ben Mamoun C., Cytochrome b Drug Resistance Mutation Decreases Babesia Fitness in the Tick Stages But Not the Mammalian Erythrocytic Cycle, J Infect Dis. 2022 Jan 5;225(1):135-145. doi: 10.1093/infdis/jiab321.
Chand M, Choi JY, Pal AC, Singh P, Kumari V, Thekkiniath J, Gagnon J, Timalsina S, Gaur G, Williams S, Ledizet M, Mamoun CB., Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti, Front Cell Infect Microbiol. 2022 Nov 25;12:1039197. doi: 10.3389/fcimb.2022.1039197. eCollection 2022.
Case EDR, Mahapatra S, Hoffpauir CT, Konganti K, Hillhouse AE, Samuel JE, Van Schaik EJ., Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii, Microbiol Spectr. 2022 Aug 31;10(4):e0248421. doi: 10.1128/spectrum.02484-21. Epub 2022 Aug 1.
Oncology
Avena P, Casaburi I, Zavaglia L, Nocito MC, La Padula D, Rago V, Dong J, Thomas P, Mineo C, Sirianni R, Shaul PW., 27-Hydroxycholesterol Binds GPER and Induces Progression of Estrogen Receptor-Negative Breast Cancer, Cancers (Basel). 2022 Mar 16;14(6):1521. doi: 10.3390/cancers14061521.
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Heyza JR, Ekinci E, Lindquist J, Lei W, Yunker C, Vinothkumar V, Rowbotham R, Polin L, Snider NG, Van Buren E, Watza D, Back JB, Chen W, Mamdani H, Schwartz AG, Turchi JJ, Bepler G, Patrick SM., ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe, NAR Cancer. 2023 Jan 11;5(1):zcac045. doi: 10.1093/narcan/zcac045. eCollection 2023 Mar.
Heyza JR, Ekinci E, Lindquist J, Lei W, Yunker C, Vinothkumar V, Rowbotham R, Polin L, Snider NG, Van Buren E, Watza D, Back JB, Chen W, Mamdani H, Schwartz AG, Turchi JJ, Bepler G, Patrick SM., ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe., NAR Cancer. 2023 Jan 11;5(1):zcac045. doi: 10.1093/narcan/zcac045. eCollection 2023 Mar.
Do, T. V., Hirst, J., Hyter, S., Roby, K. F., & Godwin, A. K. (2017)., Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cells., Oncotarget, 8(31), 50376-50392. doi:10.18632/oncotarget.18970 [doi]
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McKnight BN, Kim S, Boerner JL, Viola NT., Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer, Breast Cancer Res. 2020 Apr 15;22(1):37. doi: 10.1186/s13058-020-01270-1.
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Han, Chanhee; Perrone, Emanuele; Zeybek, Burak; Bellone, Stefania; Tymon-Rosario, Joan; Altwerger, Gary; Menderes, Gulden; Feinberg, Jacqueline; Haines, Kaitlin; Muller Karger, Mariana Espinal; Bianchi, Anna; Zammataro, Luca; Manzano, Aranzazu; Bonazzoli, Elena; Manara, Paola; Buza, Natalia; Hui, Pei; Ratner, Elena; Silasi, Dan-Arin; Huang, Gloria S; Azodi, Masoud; Schwartz, Peter E; Lopez, Salvatore; Santin, Alessandro D, In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma., Gynecologic oncology Vol.10, 2019
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