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General studies

Altshuler A, Amitai-Lange A, Tarazi N, Dey S, Strinkovsky L, Hadad-Porat S, Bhattacharya S, Nasser W, Imeri J, Ben-David G, Abboud-Jarrous G, Tiosano B, Berkowitz E, Karin N, Savir Y, Shalom-Feuerstein R., Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing, Cell Stem Cell. 2021 Jul 1;28(7):1248-1261.e8. doi: 10.1016/j.stem.2021.04.003. Epub 2021 May 12.

Immunology

Reuter, J. D., Fang, X., Ly, C. S., Suter, K. K., & Gibbs, D. (2012), Assessment of hazard risk associated with the intravenous use of viral vectors in rodents, Comparative Medicine, 62(5), 361-370.
Gunasekaran, K., Pentony, M., Shen, M., Garrett, L., Forte, C., Woodward, A., . . . Yan, W. (2010)., Enhancing antibody fc heterodimer formation through electrostatic steering effects: Applications to bispecific molecules and monovalent IgG, The Journal of Biological Chemistry, 285(25), 19637-19646. doi:10.1074/jbc.M110.117382 [doi]
Wooddell, C. I., Rozema, D. B., Hossbach, M., John, M., Hamilton, H. L., Chu, Q., . . . Lewis, D. L. (2013)., Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection., Molecular Therapy : The Journal of the American Society of Gene Therapy, 21(5), 973-985. doi:10.1038/mt.2013.31 [doi]
Precechtelova, J., Borsanyiova, M., Stipalova, D., Sarmirova, S., Gomolcak, P., Berakova, K., & Bopegamage, S. (2015)., Pathophysiology of the pancreas after oral infection of genetically diverse mice with coxsackievirus B4-E2, Archives of Virology, 160(1), 103-115. doi:10.1007/s00705-014-2236-7 [doi]
Oberst, M. D., Auge, C., Morris, C., Kentner, S., Mulgrew, K., McGlinchey, K., . . . Hammond, S. A. (2018)., Potent immune modulation by MEDI6383, an engineered human OX40 ligand IgG4P fc fusion protein., Molecular Cancer Therapeutics, 17(5), 1024-1038. doi:10.1158/1535-7163.MCT-17-0200 [doi]
Melis, M. H., Simpson, K. L., Dovedi, S. J., Welman, A., MacFarlane, M., Dive, C., . . . Illidge, T. M. (2013)., Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response, Cell Death and Differentiation, 20(5), 765-773. doi:10.1038/cdd.2013.8 [doi]
Lin, G. H. Y., Chai, V., Lee, V., Dodge, K., Truong, T., Wong, M., . . . Viller, N. N. (2017)., TTI-621 (SIRPalphaFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets, PloS One, 12(10), e0187262. doi:10.1371/journal.pone.0187262 [doi]

Oncology

Van Impe, K., Bethuyne, J., Cool, S., Impens, F., Ruano-Gallego, D., De Wever, O., . . . Gettemans, J. (2013), A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis., Breast Cancer Research : BCR, 15(6), R116. doi:10.1186/bcr3585 [doi]
Falah, Mizied; Rayan, Mahmoud; Rayan, Anwar, A Novel Paclitaxel Conjugate with Higher Efficiency and Lower Toxicity: A New Drug Candidate for Cancer Treatment., International journal of molecular sciences Vol.20, 2019
Grillo E, Corsini M, Ravelli C, di Somma M, Zammataro L, Monti E, Presta M, Mitola S., A novel variant of VEGFR2 identified by a pan-cancer screening of recurrent somatic mutations in the catalytic domain of tyrosine kinase receptors enhances tumor growth and metastasis, Cancer Lett. 2021 Jan 1;496:84-92. doi: 10.1016/j.canlet.2020.09.027. Epub 2020 Oct 6.
Hoogi, Shiran; Eisenberg, Vasyl; Mayer, Shimrit; Shamul, Astar; Barliya, Tilda; Cohen, Cyrille J, A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function, Journal for immunotherapy of cancer Vol.7, 2019
Jackson TR, Vuorinen A, Josa-Culleré L, Madden KS, Conole D, Cogswell TJ, Wilkinson IVL, Kettyle LM, Zhang D, O'Mahony A, Gracias D, McCall L, Westwood R, Terstappen GC, Davies SG, Tate EW, Wynne GM, Vyas P, Russell AJ, Milne TA., A tubulin binding molecule drives differentiation of acute myeloid leukemia cells, iScience. 2022 Jul 19;25(8):104787. doi: 10.1016/j.isci.2022.104787. eCollection 2022 Aug 19.
Zarrinkar, P. P., Gunawardane, R. N., Cramer, M. D., Gardner, M. F., Brigham, D., Belli, B., . . . Bhagwat, S. S. (2009), AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)., Blood, 114(14), 2984-2992. doi:10.1182/blood-2009-05-222034 [doi]
Bruckheimer, E. M., Fazenbaker, C. A., Gallagher, S., Mulgrew, K., Fuhrmann, S., Coffman, K. T., . . . Coats, S. (2009)., Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors., Neoplasia (New York, N.Y.), 11(6), 509-17, 2 p following 517.
Yen, W. C., Fischer, M. M., Hynes, M., Wu, J., Kim, E., Beviglia, L., . . . Hoey, T. (2012), Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-notch signaling in both tumor and vasculature cells., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(19), 5374-5386. doi:10.1158/1078-0432.CCR-12-0736 [doi]
Damelin, M., Bankovich, A., Park, A., Aguilar, J., Anderson, W., Santaguida, M., . . . Dylla, S. J. (2015)., Anti-EFNA4 calicheamicin conjugates effectively target triple-negative breast and ovarian tumor-initiating cells to result in sustained tumor regressions, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(18), 4165-4173. doi:10.1158/1078-0432.CCR-15-0695 [doi]
Hassler, M. R., Klisaroska, A., Kollmann, K., Steiner, I., Bilban, M., Schiefer, A. I., . . . Egger, G. (2012)., Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma., Biochimie, 94(11), 2297-2307. doi:10.1016/j.biochi.2012.05.029 [doi]
Hallin J, Bowcut V, Calinisan A, Briere DM, Hargis L, Engstrom LD, Laguer J, Medwid J, Vanderpool D, Lifset E, Trinh D, Hoffman N, Wang X, David Lawson J, Gunn RJ, Smith CR, Thomas NC, Martinson M, Bergstrom A, Sullivan F, Bouhana K, Winski S, He L, Fernandez-Banet J, Pavlicek A, Haling JR, Rahbaek L, Marx MA, Olson P, Christensen JG., Anti-tumor efficacy of a potent and selective non-covalent KRAS(G12D) inhibitor, Nat Med. 2022 Oct;28(10):2171-2182. doi: 10.1038/s41591-022-02007-7. Epub 2022 Oct 10.
Dold, C., Rodriguez Urbiola, C., Wollmann, G., Egerer, L., Muik, A., Bellmann, L., . . . von Laer, D. (2016)., Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy., Molecular Therapy Oncolytics, 3, 16021. doi:10.1038/mto.2016.21 [doi]
Cosco, D., Paolino, D., De Angelis, F., Cilurzo, F., Celia, C., Di Marzio, L., . . . Fresta, M. (2015), Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response, European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 89, 30-39. doi:10.1016/j.ejpb.2014.11.012 [doi]
Was, H., Barszcz, K., Czarnecka, J., Kowalczyk, A., Bernas, T., Uzarowska, E., . . . Sikora, E. (2017)., Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice., Oncotarget, 8(6), 9303-9322. doi:10.18632/oncotarget.14066 [doi]
Londono-Joshi, A. I., Oliver, P. G., Li, Y., Lee, C. H., Forero-Torres, A., LoBuglio, A. F., & Buchsbaum, D. J. (2012)., Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity, Breast Cancer Research and Treatment, 133(2), 437-445. doi:10.1007/s10549-011-1763-0 [doi]
Khawaja H, Briggs R, Latimer CH, Rassel M, Griffin D, Hanson L, Bardelli A, Di Nicolantonio F, McDade SS, Scott CJ, Lambe S, Maurya M, Lindner AU, Prehn JHM, Sousa J, Winnington C, LaBonte MJ, Ross S, Van Schaeybroeck S., Bcl-xL Is a Key Mediator of Apoptosis Following KRASG12C Inhibition in KRASG12C-mutant Colorectal Cancer., Mol Cancer Ther. 2023 Jan 3;22(1):135-149. doi: 10.1158/1535-7163.MCT-22-0301.
Wang, L., Park, P., Zhang, H., La Marca, F., Claeson, A., Than, K., . . . Lin, C. Y. (2012)., BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation, International Journal of Cancer.Journal International Du Cancer, 131(8), 1941-1950. doi:10.1002/ijc.27444 [doi]
Wang, L., Park, P., La Marca, F., Than, K., Rahman, S., & Lin, C. Y. (2013)., Bone formation induced by BMP-2 in human osteosarcoma cells., International Journal of Oncology, 43(4), 1095-1102. doi:10.3892/ijo.2013.2030 [doi]
Gaudio, E., Tarantelli, C., Ponzoni, M., Odore, E., Rezai, K., Bernasconi, E., . . . Bertoni, F. (2016)., Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma, Oncotarget, 7(36), 58142-58147. doi:10.18632/oncotarget.10983 [doi]
Sharma, Sambad; Wu, Shih-Ying; Jimenez, Hugo; Xing, Fei; Zhu, Dongqin; Liu, Yin; Wu, Kerui; Tyagi, Abhishek; Zhao, Dan; Lo, Hui-Wen; Metheny-Barlow, Linda; Sun, Peiqing; Bourland, John D; Chan, Michael D; Thomas, Alexandra; Barbault, Alexandre; DAgostino, Ralph B; Whitlow, Christopher T; Kirchner, Volker; Blackman, Carl; Pasche, Boris; Watabe, Kounosuke;, Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF., EBioMedicine Vol.44, 2019
Gatt, S., & Dagan, A. (2012), Cancer and sphingolipid storage disease therapy using novel synthetic analogs of sphingolipids, Chemistry and Physics of Lipids, 165(4), 462-474. doi:10.1016/j.chemphyslip.2012.02.006 [doi]
Sullivan KMC, Vilalta M, Ertl LS, Wang Y, Dunlap C, Ebsworth K, Zhao BN, Li S, Zeng Y, Miao Z, Fan P, Mali V, Lange C, McMurtrie D, Yang J, Lui R, Scamp R, Chhina V, Kumamoto A, Yau S, Dang T, Easterday A, et al., CCX559 is a potent, orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity., PLoS One. 2023 Jun 7;18(6):e0286724. doi: 10.1371/journal.pone.0286724. eCollection 2023.
Castelli R, Taranto S, Furiassi L, Bozza N, Marseglia G, Ferlenghi F, Rivara S, Retini M, Bedini A, Spadoni G, Matarazzo S, Ronca R, Presta M, Mor M, Giacomini A., Chemical modification of NSC12 leads to a specific FGF-trap with antitumor activity in multiple myeloma, Eur J Med Chem. 2021 Oct 5;221:113529. doi: 10.1016/j.ejmech.2021.113529. Epub 2021 May 5.
Liapis E, Karlas A, Klemm U, Ntziachristos V., Chemotherapeutic effects on breast tumor hemodynamics revealed by eigenspectra multispectral optoacoustic tomography (eMSOT), Theranostics. 2021 Jun 26;11(16):7813-7828. doi: 10.7150/thno.56173. eCollection 2021.
Zaoui, K., Bossow, S., Grossardt, C., Leber, M. F., Springfeld, C., Plinkert, P. K., . . . Ungerechts, G. (2012)., Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus., Cancer Gene Therapy, 19(3), 181-191. doi:10.1038/cgt.2011.75 [doi]
Feng, Yashu; Zhang, Ling; Wu, Jieying; Khadka, Bijay; Fang, Zhigang; Gu, Jiaming; Tang, Baoqiang; Xiao, Ruozhi; Pan, Guangjin; Liu, Jiajun;, CircRNA circ_0000190 inhibits the progression of multiple myeloma through modulating miR-767-5p/MAPK4 pathway., Journal of experimental & clinical cancer research : CR Vol.38, 2019
Sun, L., Zhang, L., Qian, J., Yang, J., Yi, Q., Dong, W., & Wang, M. (2012)., Combination of atiprimod and the proteasome inhibitor bortezomib induces apoptosis of mantle cell lymphoma in vitro and in vivo., Leukemia Research, 36(3), 363-368. doi:10.1016/j.leukres.2011.09.014 [doi]
Gaudio, E., Tarantelli, C., Kwee, I., Barassi, C., Bernasconi, E., Rinaldi, A., . . . Bertoni, F. (2016)., Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas., Annals of Oncology : Official Journal of the European Society for Medical Oncology, 27(6), 1123-1128. doi:10.1093/annonc/mdw131 [doi]
Benguigui, Madeleine; Weitz, Iris S; Timaner, Michael; Kan, Tal; Shechter, Dvir; Perlman, Or; Sivan, Sarit; Raviv, Ziv; Azhari, Haim; Shaked, Yuval;, Copper oxide nanoparticles inhibit pancreatic tumor growth primarily by targeting tumor initiating cells., Scientific reports Vol.9, 2019
Cosco, D., Cilurzo, F., Maiuolo, J., Federico, C., Di Martino, M. T., Cristiano, M. C., . . . Paolino, D. (2015)., Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma., Scientific Reports, 5, 17579. doi:10.1038/srep17579 [doi]
Yang N, Yang Y, Huang Z, Chen HW., Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer, Cancers (Basel). 2022 Jun 24;14(13):3110. doi: 10.3390/cancers14133110.
Aasen, Synnøve Nymark; Parajuli, Himalaya; Hoang, Tuyen; Feng, Zichao; Stokke, Krister; Wang, Jiwei; Roy, Kislay; Bjerkvig, Rolf; Knappskog, Stian; Thorsen, Frits;, Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors., International journal of molecular sciences Vol.20, 2019
Shir, A., Ogris, M., Roedl, W., Wagner, E., & Levitzki, A. (2011), EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 17(5), 1033-1043. doi:10.1158/1078-0432.CCR-10-1140 [doi]
Krishnamoorthy, Gnana P; Davidson, Natalie R; Leach, Steven D; Zhao, Zhen; Lowe, Scott W; Lee, Gina; Landa, I?igo; Nagarajah, James; Saqcena, Mahesh; Singh, Kamini; Wendel, Hans-Guido; Dogan, Snjezana; Tamarapu, Prasanna P; Blenis, John; Ghossein, Ronald A; Knauf, Jeffrey A; Rätsch, Gunnar; Fagin, James A, EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC., Cancer discovery Vol.9, 2019
Suominen MI, Knuuttila M, Schatz CA, Schlicker A, Vääräniemi J, Sjöholm B, Alhoniemi E, Haendler B, Mumberg D, Käkönen SM, Scholz A., Enhanced Antitumor Efficacy of Radium-223 and Enzalutamide in the Intratibial LNCaP Prostate Cancer Model., Int J Mol Sci. 2023 Jan 22;24(3). pii: 2189. doi: 10.3390/ijms24032189.
La Rocca, Francesco; Airoldi, Irma; Di Carlo, Emma; Marotta, Pina; Falco, Geppino; Simeon, Vittorio; Laurenzana, Ilaria; Trino, Stefania; De Luca, Luciana; Todoerti, Katia; Villani, Oreste; Lackmann, Martin; DAuria, Fiorella; Frassoni, Francesco; Neri, Antonino; Del Vecchio, Luigi; Musto, Pellegrino; Cilloni, Daniela; Caivano, Antonella;, EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells., Cellular oncology (Dordrecht) Vol.40, 2017
Zong X, Wang W, Ozes A, Fang F, Sandusky GE, Nephew KP., EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells, Cancer Res. 2020 Oct 15;80(20):4371-4385. doi: 10.1158/0008-5472.CAN-20-0458. Epub 2020 Aug 19.
Ronca R, Ghedini GC, Maccarinelli F, Sacco A, Locatelli SL, Foglio E, Taranto S, Grillo E, Matarazzo S, Castelli R, Paganini G, Desantis V, Cattane N, Cattaneo A, Mor M, Carlo-Stella C, Belotti A, Roccaro AM, Presta M, Giacomini A., FGF Trapping Inhibits Multiple Myeloma Growth through c-Myc Degradation-Induced Mitochondrial Oxidative Stress, Cancer Res. 2020 Jun 1;80(11):2340-2354. doi: 10.1158/0008-5472.CAN-19-2714. Epub 2020 Feb 24.
Paolino, D., Licciardi, M., Celia, C., Giammona, G., Fresta, M., & Cavallaro, G. (2012)., Folate-targeted supramolecular vesicular aggregates as a new frontier for effective anticancer treatment in in vivo model., European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 94-102. doi:10.1016/j.ejpb.2012.06.001 [doi]
Paolino, D., Cosco, D., Celano, M., Moretti, S., Puxeddu, E., Russo, D., & Fresta, M. (2013)., Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer, Nanomedicine (London, England), 8(2), 193-201. doi:10.2217/nnm.12.101 [doi]
Solimando AG, Da Vià  MC, Leone P, Borrelli P, Croci GA, Tabares P, Brandl A, Di Lernia G, Bianchi FP, Tafuri S, Steinbrunn T, Balduini A, Melaccio A, De Summa S, Argentiero A, Rauert-Wunderlich H, Frassanito MA, Ditonno P, Henke E, Klapper W, Ria R, Terragna C, Rasche L, Rosenwald A, Kortüm KM, Cavo M, Ribatti D, Racanelli V, Einsele H, Vacca A, Beilhack A., Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression, Haematologica. 2020 Apr 30:haematol.2019.239913. doi: 10.3324/haematol.2019.239913. Online ahead of print.
Litzenburger, B. C., Creighton, C. J., Tsimelzon, A., Chan, B. T., Hilsenbeck, S. G., Wang, T., . . . Lee, A. V. (2011), High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 17(8), 2314-2327. doi:10.1158/1078-0432.CCR-10-1903 [doi]
Shin, D. Y., Kim, A., Kang, H. J., Park, S., Kim, D. W., & Lee, S. S. (2015)., Histone deacetylase inhibitor romidepsin induces efficient tumor cell lysis via selective down-regulation of LMP1 and c-myc expression in EBV-positive diffuse large B-cell lymphoma, Cancer Letters, 364(2), 89-97. doi:10.1016/j.canlet.2015.03.016 [doi]
Lu, Y., Liu, Y., Oeck, S., & Glazer, P. M. (2018)., Hypoxia promotes resistance to EGFR inhibition in NSCLC cells via the histone demethylases, LSD1 and PLU-1., Molecular Cancer Research : MCR, 16(10), 1458-1469. doi:10.1158/1541-7786.MCR-17-0637 [doi]
Stewart, R., Morrow, M., Hammond, S. A., Mulgrew, K., Marcus, D., Poon, E., . . . McCourt, M. (2015)., Identification and characterization of MEDI4736, an antagonistic anti-PD-L1 monoclonal antibody., Cancer Immunology Research, 3(9), 1052-1062. doi:10.1158/2326-6066.CIR-14-0191 [doi]
Buoncervello, M., Romagnoli, G., Buccarelli, M., Fragale, A., Toschi, E., Parlato, S., . . . Gabriele, L. (2016), IFN-alpha potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer., Oncotarget, 7(18), 26361-26373. doi:10.18632/oncotarget.8379 [doi]
Airoldi, I., Di Carlo, E., Cocco, C., Caci, E., Cilli, M., Sorrentino, C., . . . Pistoia, V. (2009)., IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions., PloS One, 4(7), e6119. doi:10.1371/journal.pone.0006119 [doi]
Aasen, Synnøve Nymark; Espedal, Heidi; Holte, Christopher Florian; Keunen, Olivier; Karlsen, Tine Veronika; Tenstad, Olav; Maherally, Zaynah; Miletic, Hrvoje; Hoang, Tuyen; Eikeland, Anne Vaag; Baghirov, Habib; Olberg, Dag Erlend; Pilkington, Geoffrey John; Sarkar, Gobinda; Jenkins, Robert B; Sundstrøm, Terje; Bjerkvig, Rolf; Thorsen, Frits;, Improved Drug Delivery to Brain Metastases by Peptide-Mediated Permeabilization of the Blood-Brain Barrier., Molecular cancer therapeutics Vol.18, 2019
Di Martino, M. T., Gulla, A., Gallo Cantafio, M. E., Altomare, E., Amodio, N., Leone, E., . . . Tassone, P. (2014, In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells., PloS One, 9(2), e89659. doi:10.1371/journal.pone.0089659 [doi]
Hofmann, M., McCormack, E., Mujic, M., Rossberg, M., Bernd, A., Bereiter-Hahn, J., . . . Kippenberger, S. (2009)., Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model, Neoplasia (New York, N.Y.), 11(8), 812-822.
Kuang Y, Ye N, Kyani A, Ljungman M, Paulsen M, Chen H, Zhou M, Wild C, Chen H, Zhou J, Neamati N., Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer, J Med Chem. 2022 Apr 28;65(8):6133-6156. doi: 10.1021/acs.jmedchem.1c02207. Epub 2022 Apr 19.
Otto, Marius; Blatt, Sebastian; Pabst, Andreas; Mandic, Robert; Schwarz, Johanna; Neff, Andreas; Ziebart, Thomas;, Influence of buffy coat-derived putative endothelial progenitor cells on tumor growth and neovascularization in oral squamous cell carcinoma xenografts., Clinical oral investigations Vol.23, 2019
Boer, J. C., Domanska, U. M., Timmer-Bosscha, H., Boer, I. G., de Haas, C. J., Joseph, J. V., . . . Walenkamp, A. M. (2013), Inhibition of formyl peptide receptor in high-grade astrocytoma by CHemotaxis inhibitory protein of S. aureus., British Journal of Cancer, 108(3), 587-596. doi:10.1038/bjc.2012.603 [doi]
Lamanuzzi, A., Saltarella, I., Desantis, V., Frassanito, M. A., Leone, P., Racanelli, V., . . . Ria, R. (2018)., Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma., Oncotarget, 9(29), 20563-20577. doi:10.18632/oncotarget.25003 [doi]
Rodriguez-Barrueco, R., Yu, J., Saucedo-Cuevas, L. P., Olivan, M., Llobet-Navas, D., Putcha, P., . . . Silva, J. M. (2015)., Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers, Genes & Development, 29(15), 1631-1648. doi:10.1101/gad.262642.115 [doi]
Burns, T. F., Dobromilskaya, I., Murphy, S. C., Gajula, R. P., Thiyagarajan, S., Chatley, S. N., . . . Rudin, C. M. (2013)., Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer, Molecular Cancer Research : MCR, 11(4), 329-338. doi:10.1158/1541-7786.MCR-12-0456 [doi]
Wang T, Gnanaprakasam JNR, Chen X, Kang S, Xu X, Sun H, Liu L, Rodgers H, Miller E, Cassel TA, Sun Q, Vicente-MuĂąoz S, Warmoes MO, Lin P, Piedra-Quintero ZL, Guerau-de-Arellano M, Cassady KA, Zheng SG, Yang J, Lane AN, Song X, Fan TW, Wang R., Inosine is an alternative carbon source for CD8(+)-T-cell function under glucose restriction, Nat Metab. 2020 Jul;2(7):635-647. doi: 10.1038/s42255-020-0219-4. Epub 2020 Jun 15.
Haas, T. L., Sciuto, M. R., Brunetto, L., Valvo, C., Signore, M., Fiori, M. E., . . . De Maria, R. (2017)., Integrin alpha7 is a functional marker and potential therapeutic target in glioblastoma, Cell Stem Cell, 21(1), 35-50.e9. doi:S1934-5909(17)30137-6 [pii]
Cocco, C., Giuliani, N., Di Carlo, E., Ognio, E., Storti, P., Abeltino, M., . . . Airoldi, I. (2010), Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 16(16), 4188-4197. doi:10.1158/1078-0432.CCR-10-0173 [doi]
Airoldi, I., Tupone, M. G., Esposito, S., Russo, M. V., Barbarito, G., Cipollone, G., & Di Carlo, E. (2015)., Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer., Oncotarget, 6(6), 3694-3708. doi:2797 [pii]
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Lapenta, Caterina; Donati, Simona; Spadaro, Francesca; Lattanzi, Laura; Urbani, Francesca; Macchia, Iole; Sestili, Paola; Spada, Massimo; Cox, Maria Christina; Belardelli, Filippo; Santini, Stefano M, Lenalidomide improves the therapeutic effect of an interferon-Îą-dendritic cell-based lymphoma vaccine., Cancer immunology, immunotherapy : CII Vol.68, 2019
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Punzi, Simona; Balestrieri, Chiara; DAlesio, Carolina; Bossi, Daniela; Dellino, Gaetano Ivan; Gatti, Elena; Pruneri, Giancarlo; Criscitiello, Carmen; Lovati, Giulia; Meliksetyan, Marine; Carugo, Alessandro; Curigliano, Giuseppe; Natoli, Gioacchino; Pelicci, Pier Giuseppe; Lanfrancone, Luisa;, WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells., Breast cancer research : BCR Vol.21, 2019
Fischer, M. M., Cancilla, B., Yeung, V. P., Cattaruzza, F., Chartier, C., Murriel, C. L., . . . Hoey, T. (2017)., WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death, Science Advances, 3(6), e1700090. doi:10.1126/sciadv.1700090 [doi]
Sabatino, M. A., Geroni, C., Ganzinelli, M., Ceruti, R., & Broggini, M. (2013)., Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin, Epigenetics, 8(6), 656-665. doi:10.4161/epi.24916 [doi]

Other

Grillo E, Corsini M, Ravelli C, di Somma M, Zammataro L, Monti E, Presta M, Mitola S., A novel variant of VEGFR2 identified by a pan-cancer screening of recurrent somatic mutations in the catalytic domain of tyrosine kinase receptors enhances tumor growth and metastasis, Cancer Lett. 2021 Jan 1;496:84-92. doi: 10.1016/j.canlet.2020.09.027. Epub 2020 Oct 6.
O'Kelly D, Campbell J 3rd, Gerberich JL, Karbasi P, Malladi V, Jamieson A, Wang L, Mason RP., A scalable open-source MATLAB toolbox for reconstruction and analysis of multispectral optoacoustic tomography data, Sci Rep. 2021 Oct 6;11(1):19872. doi: 10.1038/s41598-021-97726-1.
Bownes LV, Williams AP, Marayati R, Stafman LL, Markert H, Quinn CH, Wadhwani N, Aye JM, Stewart JE, Yoon KJ, Mroczek-Musulman E, Beierle EA., EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth, PLoS One. 2021 Mar 9;16(3):e0246244. doi: 10.1371/journal.pone.0246244. eCollection 2021.
Solimando AG, Da Viŕ MC, Leone P, Borrelli P, Croci GA, Tabares P, Brandl A, Di Lernia G, Bianchi FP, Tafuri S, Steinbrunn T, Balduini A, Melaccio A, De Summa S, Argentiero A, Rauert-Wunderlich H, Frassanito MA, Ditonno P, Henke E, Klapper W, Ria R, Terragna C, Rasche L, Rosenwald A, Kortüm MK, Cavo M, Ribatti D, Racanelli V, Einsele H, Vacca A, Beilhack A., Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression, Haematologica. 2021 Jul 1;106(7):1943-1956. doi: 10.3324/haematol.2019.239913.
Ghosh M, Saha S, Bettke J, Nagar R, Parrales A, Iwakuma T, van der Velden AWM, Martinez LA., Mutant p53 suppresses innate immune signaling to promote tumorigenesis, Cancer Cell. 2021 Apr 12;39(4):494-508.e5. doi: 10.1016/j.ccell.2021.01.003. Epub 2021 Feb 4.
Kosenko A, Salame TM, Fridlander G, Barash I., Newly characterized bovine mammary stromal region with epithelial properties supports representative epithelial outgrowth development from transplanted stem cells, Cell Tissue Res. 2021 Oct 26. doi: 10.1007/s00441-021-03545-1. Online ahead of print.
Urbano N, Scimeca M, Tolomeo A, Dimiccoli V, Bonanno E, Schillaci O., Novel Biological and Molecular Characterization in Radiopharmaceutical Preclinical Design, J Clin Med. 2021 Oct 21;10(21):4850. doi: 10.3390/jcm10214850.
Marayati R, Stafman LL, Williams AP, Bownes LV, Quinn CH, Aye JM, Stewart JE, Yoon KJ, Anderson JC, Willey CD, Beierle EA., PIM kinases mediate resistance to cisplatin chemotherapy in hepatoblastoma, Sci Rep. 2021 Mar 16;11(1):5984. doi: 10.1038/s41598-021-85289-0.
Castillo-Ecija H, Pascual-Pasto G, Perez-Jaume S, Resa-Pares C, Vila-Ubach M, Monterrubio C, Jimenez-Cabaco A, Baulenas-Farres M, Muńoz-Aznar O, Salvador N, Cuadrado-Vilanova M, Olaciregui NG, Balaguer-Lluna L, Burgueńo V, Vicario FJ, Manzanares A, Castańeda A, Santa-Maria V, Cruz O, Celis V, Morales La Madrid A, Garraus M, Gorostegui M, Vancells M, Carrasco R, Krauel L, Torner F, Suńol M, Lavarino C, Mora J, Carcaboso AM., Prognostic value of patient-derived xenograft engraftment in pediatric sarcomas, J Pathol Clin Res. 2021 Jul;7(4):338-349. doi: 10.1002/cjp2.210. Epub 2021 Apr 9.
Appolloni I, Alessandrini F, Menotti L, Avitabile E, Marubbi D, Piga N, Ceresa D, Piaggio F, Campadelli-Fiume G, Malatesta P., Specificity, Safety, Efficacy of EGFRvIII-Retargeted Oncolytic HSV for Xenotransplanted Human Glioblastoma, Viruses. 2021 Aug 24;13(9):1677. doi: 10.3390/v13091677.
Jayaram DR, Frost S, Argov C, Liju VB, Anto NP, Muraleedharan A, Ben-Ari A, Sinay R, Smoly I, Novoplansky O, Isakov N, Toiber D, Keasar C, Elkabets M, Yeger-Lotem E, Livneh E., Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs, Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2018899118. doi: 10.1073/pnas.2018899118. Epub 2021 Sep 30.

Transplantation

Maldonado, A. A., Cristobal, L., Martin-Lopez, J., Mallen, M., Garcia-Honduvilla, N., & Bujan, J. (2014)., A novel model of human skin pressure ulcers in mice., PloS One, 9(10), e109003. doi:10.1371/journal.pone.0109003 [doi]
Wang, L., Rahman, S., Lin, C. Y., Valdivia, J., Than, K., La Marca, F., & Park, P. (2012)., A novel murine model of human renal cell carcinoma spinal metastasis., Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 19(6), 881-883. doi:10.1016/j.jocn.2011.10.019 [doi]
Zhang, Y., Zheng, D., Zhou, T., Song, H., Hulsurkar, M., Su, N., . . . Li, W. (2018)., Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers., Nature Communications, 9(1), 4080-018-06177-2. doi:10.1038/s41467-018-06177-2 [doi]
Hamilton NJI, Lee DDH, Gowers KHC, Butler CR, Maughan EF, Jevans B, Orr JC, McCann CJ, Burns AJ, MacNeil S, Birchall MA, O'Callaghan C, Hynds RE, Janes SM., Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds, Eur Respir J. 2020 Jun 18;55(6):1901200. doi: 10.1183/13993003.01200-2019. Print 2020 Jun.
Magrassi L, Nato G, Delia D, Buffo A., Cell-Autonomous Processes That Impair Xenograft Survival into the Cerebellum, Cerebellum. 2022 Oct;21(5):821-825. doi: 10.1007/s12311-022-01414-3. Epub 2022 May 16.
Milazzo, L., Vulcano, F., Barca, A., Macioce, G., Paldino, E., Rossi, S., . . . Giampaolo, A. (2014)., Cord blood CD34+ cells expanded on wharton's jelly multipotent mesenchymal stromal cells improve the hematopoietic engraftment in NOD/SCID mice, European Journal of Haematology, 93(5), 384-391. doi:10.1111/ejh.12363 [doi]
Westenfelder, C., Gooch, A., Hu, Z., Ahlstrom, J., & Zhang, P. (2017)., Durable control of autoimmune diabetes in mice achieved by intraperitoneal transplantation of "neo-islets," three-dimensional aggregates of allogeneic islet and "mesenchymal stem cells", Stem Cells Translational Medicine, 6(7), 1631-1643. doi:10.1002/sctm.17-0005 [doi]
Argyros, O., Wong, S. P., Gowers, K., & Harbottle, R. P. (2012)., Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling., PloS One, 7(10), e47920. doi:10.1371/journal.pone.0047920 [doi]
Nato G, Corti A, Parmigiani E, Jachetti E, Lecis D, Colombo MP, Delia D, Buffo A, Magrassi L., Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing, Sci Rep. 2021 Jan 12;11(1):651. doi: 10.1038/s41598-020-79502-9.
Glaeser JD, Bao X, Kaneda G, Avalos P, Behrens P, Salehi K, Da X, Chen A, Castaneda C, Nakielski P, Jiang W, Tawackoli W, Sheyn D., iPSC-neural crest derived cells embedded in 3D printable bio-ink promote cranial bone defect repair, Sci Rep. 2022 Nov 4;12(1):18701. doi: 10.1038/s41598-022-22502-8.
Govaere, O., Wouters, J., Petz, M., Vandewynckel, Y. P., Van den Eynde, K., Van den Broeck, A., . . . Roskams, T. (2016)., Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche., Journal of Hepatology, 64(3), 609-617. doi:10.1016/j.jhep.2015.11.011 [doi]
Cristóbal, Lara; de Los Reyes, Nerea; Ortega, Miguel A; Álvarez-Mon, Melchor; García-Honduvilla, Natalio; BujĂĄn, Julia; Maldonado, AndrĂŠs A;, Local Growth Hormone Therapy for Pressure Ulcer Healing on a Human Skin Mouse Model, International journal of molecular sciences Vol.20, 2019
Loebinger, M. R., Kyrtatos, P. G., Turmaine, M., Price, A. N., Pankhurst, Q., Lythgoe, M. F., & Janes, S. M. (2009)., Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles., Cancer Research, 69(23), 8862-8867. doi:10.1158/0008-5472.CAN-09-1912 [doi]
Elovic, Edan; Etzion, Sharon; Cohen, Smadar;, MiR-499 Responsive Lethal Construct for Removal of Human Embryonic Stem Cells after Cardiac Differentiation, Scientific reports Vol.9, 2019
Marin-Ramos, N. I., Thein, T. Z., Cho, H. Y., Swenson, S. D., Wang, W., Schonthal, A. H., . . . Hofman, F. M. (2018), NEO212 inhibits migration and invasion of glioma stem cells., Molecular Cancer Therapeutics, 17(3), 625-637. doi:10.1158/1535-7163.MCT-17-0591 [doi]
Glaeser JD, Behrens P, Stefanovic T, Salehi K, Papalamprou A, Tawackoli W, Metzger MF, Eberlein S, Nelson T, Arabi Y, Kim K, Baloh RH, Ben-David S, Cohn-Schwartz D, Ryu R, Bae HW, Gazit Z, Sheyn D., Neural crest-derived mesenchymal progenitor cells enhance cranial allograft integration, Stem Cells Transl Med. 2021 May;10(5):797-809. doi: 10.1002/sctm.20-0364. Epub 2021 Jan 29.
Peled, T., Shoham, H., Aschengrau, D., Yackoubov, D., Frei, G., Rosenheimer, G. N., . . . Peled, A. (2012), Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment, Experimental Hematology, 40(4), 342-55.e1. doi:10.1016/j.exphem.2011.12.005 [doi]
Hargus, G., Ehrlich, M., Arauzo-Bravo, M. J., Hemmer, K., Hallmann, A. L., Reinhardt, P., . . . Zaehres, H. (2014)., Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain, Cell Reports, 8(6), 1697-1703. doi:10.1016/j.celrep.2014.08.014 [doi]
Owonikoko, T. K., Zhang, G., Kim, H. S., Stinson, R. M., Bechara, R., Zhang, C., . . . Khuri, F. R. (2016)., Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer, Journal of Translational Medicine, 14(1), 111-016-0861-5. doi:10.1186/s12967-016-0861-5 [doi]
Calles, A., Rubio-Viqueira, B., & Hidalgo, M. (2013)., Primary human non-small cell lung and pancreatic tumorgraft models--utility and applications in drug discovery and tumor biology., Current Protocols in Pharmacology / Editorial Board, S.J.Enna (Editor-in-Chief) ...[Et Al.], Chapter 14, Unit 14.26. doi:10.1002/0471141755.ph1426s61 [doi]
Feys, L., Descamps, B., Vanhove, C., Vermeulen, S., Vandesompele, J. O., Vanderheyden, K., . . . De Wever, O. (2016), Quantitative and functional requirements for bioluminescent cancer models., In Vivo (Athens, Greece), 30(1), 1-11. doi:30/1/1 [pii]
Buzhor, E., Omer, D., Harari-Steinberg, O., Dotan, Z., Vax, E., Pri-Chen, S., . . . Dekel, B. (2013)., Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties, The American Journal of Pathology, 183(5), 1621-1633. doi:10.1016/j.ajpath.2013.07.034 [doi]
Thomson, A. J., Pierart, H., Meek, S., Bogerman, A., Sutherland, L., Murray, H., . . . Burdon, T. (2012)., Reprogramming pig fetal fibroblasts reveals a functional LIF signaling pathway, Cellular Reprogramming, 14(2), 112-122. doi:10.1089/cell.2011.0078 [doi]
Gudlevičienė Z, Žilinskas K,Kundrotas G, Grubliauskaitė M, Baltriukienė D, Bukelskienė V., Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation, Medicina (Kaunas). 2020 Oct 19;56(10):547. doi: 10.3390/medicina56100547.
Yuan, X., Wei, Y., Villasante, A., Ng, J. J. D., Arkonac, D. E., Chao, P. G., & Vunjak-Novakovic, G. (2017)., Stem cell delivery in tissue-specific hydrogel enabled meniscal repair in an orthotopic rat model, Biomaterials, 132, 59-71. doi:S0142-9612(17)30213-2 [pii]
Lima, M. J., Muir, K. R., Docherty, H. M., Drummond, R., McGowan, N. W., Forbes, S., . . . Docherty, K. (2013), Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing beta-like cells., Diabetes, 62(8), 2821-2833. doi:10.2337/db12-1256 [doi]
Banerjee, K., Pru, C., Pru, J. K., & Resat, H. (2018)., TAT3 knockdown induces tumor formation by MDA-MB-231 cells, Clinical Oncology and Research, 1(1) doi:10.31487/j.COR.2018.10.002 [doi]
Chartier, C., Raval, J., Axelrod, F., Bond, C., Cain, J., Dee-Hoskins, C., . . . Gurney, A. (2016), Therapeutic targeting of tumor-derived R-spondin attenuates beta-catenin signaling and tumorigenesis in multiple cancer types, Cancer Research, 76(3), 713-723. doi:10.1158/0008-5472.CAN-15-0561 [doi]
Vulcano, F., Milazzo, L., Ciccarelli, C., Barca, A., Agostini, F., Altieri, I., . . . Hassan, H. J. (2012)., Valproic acid affects the engraftment of TPO-expanded cord blood cells in NOD/SCID mice., Experimental Cell Research, 318(4), 400-407. doi:10.1016/j.yexcr.2011.11.012 [doi]
Rauner, G., & Barash, I. (2014), Xanthosine administration does not affect the proportion of epithelial stem cells in bovine mammary tissue, but has a latent negative effect on cell proliferation., Experimental Cell Research, 328(1), 186-196. doi:10.1016/j.yexcr.2014.06.017 [doi]
Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., . . . Esserman, L. J. (2012)., Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors, Breast Cancer Research and Treatment, 135(3), 913-922. doi:10.1007/s10549-012-2226-y [doi]

Tumor cell growth

Friese-Hamim M, Clark A, Perrin D, Crowley L, Reusch C, Bogatyrova O, Zhang H, Crandall T, Lin J, Ma J, Bachner D, Schmidt J, Schaefer M, Stroh C., Brain penetration and efficacy of tepotinib in orthotopic patient-derived xenograft models of MET-driven non-small cell lung cancer brain metastases, Lung Cancer. 2022 Jan;163:77-86. doi: 10.1016/j.lungcan.2021.11.020. Epub 2021 Dec 11.
Kim M, Vu NT, Wang X, Bulut GB, Wang MH, Uram-Tuculescu C, Pillappa R, Kim S, Chalfant CE., Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis, Mol Cancer Res. 2022 Aug 5;20(8):1284-1294. doi: 10.1158/1541-7786.MCR-21-0905.
Zhang B, Chen Y, Bao L, Luo W., GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth, Cells. 2022 Aug 20;11(16):2597. doi: 10.3390/cells11162597.
Peuhu E, Jacquemet G, Scheele CLGJ, Isomursu A, Laisne MC, Koskinen LM, Paatero I, Thol K, Georgiadou M, Guzmán C, Koskinen S, Laiho A, Elo LL, Boström P, Hartiala P, van Rheenen J, Ivaska J., MYO10-filopodia support basement membranes at pre-invasive tumor boundaries, Dev Cell. 2022 Oct 24;57(20):2350-2364.e7. doi: 10.1016/j.devcel.2022.09.016.
Domingo-Ortí I, Ferrer-Torres P, Armiñán A, Vicent MJ, Pineda-Lucena A, Palomino-Schätzlein M., NMR-Based Mitochondria Metabolomic Profiling: A New Approach To Reveal Cancer-Associated Alterations, Anal Chem. 2023 Nov 14;95(45):16539-16548. doi: 10.1021/acs.analchem.3c02432. Epub 2023 Oct 31.
Ghosh M, Saha S, Li J, Montrose DC, Martinez LA., p53 engages the cGAS/STING cytosolic DNA sensing pathway for tumor suppression., Mol Cell. 2023 Jan 19;83(2):266-280.e6. doi: 10.1016/j.molcel.2022.12.023. Epub 2023 Jan 12.
Aschero R, Castillo-Ecija H, Baulenas-Farres M, Resa-Pares C, Jimenez-Cabaco A, Rodriguez E, Monterrubio C, Perez-Jaume S, Suñol M, Chantada GL, Lavarino C, Mora J, Carcaboso AM., Prognostic value of xenograft engraftment in patients with metastatic high-risk neuroblastoma., Pediatr Blood Cancer. 2023 Jun;70(6):e30318. doi: 10.1002/pbc.30318. Epub 2023 Mar 27.
Hidmi S, Nechushtan H, Razin E, Tshori S., Role of Nudt2 in Anchorage-Independent Growth and Cell Migration of Human Melanoma., Int J Mol Sci. 2023 Jun 22;24(13). pii: 10513. doi: 10.3390/ijms241310513.
Quinn CH, Beierle AM, Hutchins SC, Marayati R, Bownes LV, Stewart JE, Markert HR, Erwin MH, Aye JM, Yoon KJ, Friedman GK, Willey CD, Markert JM, Beierle EA., Targeting High-Risk Neuroblastoma Patient-Derived Xenografts with Oncolytic Virotherapy, Cancers (Basel). 2022 Feb 1;14(3):762. doi: 10.3390/cancers14030762.
Howley BV, Mohanty B, Dalton A, Grelet S, Karam J, Dincman T, Howe PH., The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression, Oncogene. 2022 Mar;41(12):1679-1690. doi: 10.1038/s41388-022-02199-9. Epub 2022 Jan 31.

Tumor growth

Onion, D., Argent, R. H., Reece-Smith, A. M., Craze, M. L., Pineda, R. G., Clarke, P. A., . . . Grabowska, A. M. (2016), 3-dimensional patient-derived lung cancer assays reveal resistance to standards-of-care promoted by stromal cells but sensitivity to histone deacetylase inhibitors., Molecular Cancer Therapeutics, 15(4), 753-763. doi:10.1158/1535-7163.MCT-15-0598 [doi]
Barilani M, Cherubini A, Peli V, Polveraccio F, Bollati V, Guffanti F, Del Gobbo A, Lavazza C, Giovanelli S, Elvassore N, Lazzari L., A circular RNA map for human induced pluripotent stem cells of foetal origin, EBioMedicine. 2020 Jul;57:102848. doi: 10.1016/j.ebiom.2020.102848. Epub 2020 Jun 20.
Howley, B. V., Link, L. A., Grelet, S., El-Sabban, M., & Howe, P. H. (2018)., A CREB3-regulated ER-golgi trafficking signature promotes metastatic progression in breast cancer, Oncogene, 37(10), 1308-1325. doi:10.1038/s41388-017-0023-0 [doi]
Marlow, R., Honeth, G., Lombardi, S., Cariati, M., Hessey, S., Pipili, A., . . . Dontu, G. (2013), A novel model of dormancy for bone metastatic breast cancer cells, Cancer Research, 73(23), 6886-6899. doi:10.1158/0008-5472.CAN-13-0991 [doi]
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A. P., . . . Salomoni, P. (2016), A promyelocytic leukemia protein-thrombospondin-2 axis and the risk of relapse in neuroblastoma, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(13), 3398-3409. doi:10.1158/1078-0432.CCR-15-2081 [doi]
Kalli, Maria; Mpekris, Fotios; Wong, Chen K; Panagi, Myrofora; Ozturk, Sait; Thiagalingam, Sam; Stylianopoulos, Triantafyllos; Papageorgis, Panagiotis;, Activin A Signaling Regulates IL13R??2 Expression to Promote Breast Cancer Metastasis, Frontiers in oncology Vol.9, 2019
Houben, R., Adam, C., Baeurle, A., Hesbacher, S., Grimm, J., Angermeyer, S., . . . Schrama, D. (2012), An intact retinoblastoma protein-binding site in merkel cell polyomavirus large T antigen is required for promoting growth of merkel cell carcinoma cells, International Journal of Cancer.Journal International Du Cancer, 130(4), 847-856. doi:10.1002/ijc.26076 [doi]
Okada, Seiji; Vaeteewoottacharn, Kulthida; Kariya, Ryusho;, Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models., Cells Vol.8, 2019
Krelin, Y., Berkovich, L., Amit, M., & Gil, Z. (2013)., Association between tumorigenic potential and the fate of cancer cells in a syngeneic melanoma model, PloS One, 8(4), e62124. doi:10.1371/journal.pone.0062124 [doi]
Wang, L., Park, P., La Marca, F., Than, K. D., & Lin, C. Y. (2015), BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation, Journal of Cancer Research and Clinical Oncology, 141(6), 1013-1024. doi:10.1007/s00432-014-1883-0 [doi]
Frassanito, M. A., Rao, L., Moschetta, M., Ria, R., Di Marzo, L., De Luisi, A., . . . Vacca, A. (2014), Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: In vitro and in vivo studies, Leukemia, 28(4), 904-916. doi:10.1038/leu.2013.254 [doi]
Codenotti, Silvia; Faggi, Fiorella; Ronca, Roberto; Chiodelli, Paola; Grillo, Elisabetta; Guescini, Michele; Megiorni, Francesca; Marampon, Francesco; Fanzani, Alessandro;, Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperation, Cancer letters Vol.449, 2019
Ceresa, Davide; Alessandrini, Francesco; Bosio, Lorenzo; Marubbi, Daniela; Reverberi, Daniele; Malatesta, Paolo; Appolloni, Irene;, Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells, International journal of molecular sciences Vol.20, 2019
Fareh, M., Almairac, F., Turchi, L., Burel-Vandenbos, F., Paquis, P., Fontaine, D., . . . Virolle, T. (2017)., Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth, Cell Death & Disease, 8(3), e2713. doi:10.1038/cddis.2017.117 [doi]
Salvatori, L., Caporuscio, F., Verdina, A., Starace, G., Crispi, S., Nicotra, M. R., . . . Petrangeli, E. (2012)., Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors., PloS One, 7(2), e31467. doi:10.1371/journal.pone.0031467 [doi]
James, M. I., Howells, L. M., Karmokar, A., Higgins, J. A., Greaves, P., Cai, H., . . . Brown, K. (2015)., Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: Trials, tribulations and a cautionary note, PloS One, 10(2), e0117776. doi:10.1371/journal.pone.0117776 [doi]
Schrama, David; Sarosi, Eva-Maria; Adam, Christian; Ritter, Cathrin; Kaemmerer, Ulrike; Klopocki, Eva; KĂśnig, Eva-Maria; Utikal, Jochen; Becker, JĂźrgen C; Houben, Roland;, Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration., International journal of cancer Vol.145, 2019
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