New Zealand White Rabbits
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Antibody production
Kolehmainen P, Huttunen M, Iakubovskaia A, Maljanen A, Tauriainen S, Yatkin E...Julkunen I., Coronavirus spike protein-specific antibodies
indicate frequent infections and reinfections in
infancy and among BNT162b2-vaccinated
healthcare workers, November 2022, PREPRINT (Version 1) available at Research Square.
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, Ward AB., HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite, Sci Adv. 2020 Jun 5;6(23):eaba0512. doi: 10.1126/sciadv.aba0512. eCollection 2020 Jun.
Schorcht A, van den Kerkhof TLGM, Cottrell CA, Allen JD, Torres JL, Behrens AJ, Schermer EE, Burger JA, de Taeye SW, Torrents de la PeĂąa A, Bontjer I, Gumbs S, Ozorowski G, LaBranche CC, de Val N, Yasmeen A, Klasse PJ, Montefiori DC, Moore JP, Schuitemaker H, Crispin M, van Gils MJ, Ward AB, Sanders RW., Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers, J Virol. 2020 Nov 23;94(24):e01214-20. doi: 10.1128/JVI.01214-20. Print 2020 Nov 23.
Atherosclerosis
Zabriskie MS, Wang C, Wang S, Alexander MD., Apolipoprotein E knockout rabbit model of intracranial atherosclerotic disease, Animal Model Exp Med. 2020 Jun 21;3(2):208-213. doi: 10.1002/ame2.12125. eCollection 2020 Jun.
Naito, Noritsugu; Ukita, Rei; Wilbs, Jonas; Wu, Kan; Lin, Xiaojie; Carleton, Neil M.; Roberts, Kalliope; Jiang, Shaoyi; Heinis, Christian; Cook, Keith E., Combination of polycarboxybetaine coating and factor XII inhibitor reduces clot formation while preserving normal tissue coagulation during extracorporeal life support, Biomaterials. 2021.
Riemer K, Rowland EM, Broughton-Venner J, Leow CH, Tang M, Weinberg PD., Contrast Agent-Free Assessment of Blood Flow and Wall Shear Stress in the Rabbit Aorta using Ultrasound Image Velocimetry, Ultrasound Med Biol. 2022 Mar;48(3):437-449. doi: 10.1016/j.ultrasmedbio.2021.10.010. Epub 2021 Dec 5.
Riemer K, Rowland EM, Leow CH, Tang MX, Weinberg PD., Determining Haemodynamic Wall Shear Stress in the Rabbit Aorta In Vivo Using Contrast-Enhanced Ultrasound Image Velocimetry, Ann Biomed Eng. 2020 Jun;48(6):1728-1739. doi: 10.1007/s10439-020-02484-2. Epub 2020 Mar 4.
Koike T, Koike Y, Yang D, Guo Y, Rom O, Song J, Xu J, Chen Y, Wang Y, Zhu T, Garcia-Barrio MT, Fan J, Chen YE, Zhang J., Human apolipoprotein A-II reduces atherosclerosis in knock-in rabbits, Atherosclerosis. 2021 Jan;316:32-40. doi: 10.1016/j.atherosclerosis.2020.11.028. Epub 2020 Nov 28.
Devine R, Goudie MJ, Singha P, Schmiedt C, Douglass M, Brisbois EJ, Handa H., Mimicking the Endothelium: Dual Action Heparinized Nitric Oxide Releasing Surface, ACS Appl Mater Interfaces. 2020 May 6;12(18):20158-20171. doi: 10.1021/acsami.9b22277. Epub 2020 Apr 22.
Behavioral and learning disabilities
Amin B, Robinson RAS., Dataset of quantitative proteomic analysis to understand aging processes in rabbit liver, Data Brief. 2020 May 15;31:105701. doi: 10.1016/j.dib.2020.105701. eCollection 2020 Aug.
Biomedical research
Rozema NB, Procissi D, Bertolino N, Viola KL, Nandwana V, Abdul N, Pribus S, Dravid V, Klein WL, Disterhoft JF, Weiss C., Aβ oligomer induced cognitive impairment and evaluation of ACU193-MNS-based MRI in rabbit, Alzheimers Dement (N Y). 2020 Oct 10;6(1):e12087. doi: 10.1002/trc2.12087. eCollection 2020.
Hamilton NJI, Lee DDH, Gowers KHC, Butler CR, Maughan EF, Jevans B, Orr JC, McCann CJ, Burns AJ, MacNeil S, Birchall MA, O'Callaghan C, Hynds RE, Janes SM., Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds, Eur Respir J. 2020 Jun 18;55(6):1901200. doi: 10.1183/13993003.01200-2019. Print 2020 Jun.
Tseng, Chun-Che; Dean, Shirley; Davies, Brian A.; Azmi, Ishara F.; Pashkova, Natalya; Payne, Johanna A.; Staffenhagen, Jennifer; West, Matt; Piper, Robert C.; Odorizzi, Greg; Katzmann, David J., Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis, Journal of Cell Biology. 2021.
Chua, Corrine Ying Xuan; Liu, Hsuan-Chen; Di Trani, Nicola; Susnjar, Antonia; Ho, Jeremy; Scorrano, Giovanni; Rhudy, Jessica; Sizovs, Antons; Lolli, Graziano; Hernandez, Nathanael; Nucci, Maria Concetta; Cicalo, Roberto; Ferrari, Mauro; Grattoni, Alessandro, Carbon fiber reinforced polymers for implantable medical devices, Biomaterials. 2021.
Comolli J, Schnellbacher R, Beaufrere H, Blas-Machado U, Quandt J, Mayer J, Divers SJ., Comparison of endoscopic endotracheal intubation and the v-gel supraglottic airway device for spontaneously ventilating New Zealand White Rabbits undergoing ovariohysterectomy, Vet Rec. 2020 Nov 14;187(10):e84. doi: 10.1136/vr.105746. Epub 2020 Jul 20.
Gordon AC, Gates VL, White SB, Harris KR, Procissi D, Zhang Z, Li W, Samaan D, Nicolai JR, Mouli SK, Sato KT, Ryu RK, Omary RA, Salem R, Lewandowski RJ, Larson AC., Correlation and Agreement of Yttrium-90 Positron Emission Tomography/Computed Tomography with Ex Vivo Radioembolization Microsphere Deposition in the Rabbit VX2 Liver Tumor Model, J Vasc Interv Radiol. 2021 Jan;32(1):23-32.e1. doi: 10.1016/j.jvir.2020.09.016. Epub 2020 Nov 12.
Bertolino N, Procissi D, Disterhoft JF, Weiss C., Detection of memory- and learning-related brain connectivity changes following trace eyeblink-conditioning using resting-state functional magnetic resonance imaging in the awake rabbit, J Comp Neurol. 2020 Sep 25. doi: 10.1002/cne.25042. Online ahead of print.
GĂśk C, Plain F, Robertson AD, Howie J, Baillie GS, Fraser NJ, Fuller W., Dynamic Palmitoylation of the Sodium-Calcium Exchanger Modulates Its Structure, Affinity for Lipid-Ordered Domains, and Inhibition by XIP, Cell Rep. 2020 Jun 9;31(10):107697. doi: 10.1016/j.celrep.2020.107697.
O'Shaughnessy, Danielle; Grande, Daniel; El-Neemany, Diana; Sajjan, Sujata; Pillalamarri, Nirmala; Shalom, Dara; Winkler, Harvey, Evaluation of the histological and biomechanical properties of poly-4-hydroxybutyrate scaffold for pelvic organ prolapse, compared with polypropylene mesh in a rabbit model, International Urogynecology Journal. 2021.
Luthra A, Montezuma-Rusca JM, La Vake CJ, LeDoyt M, Delgado KN, Davenport TC, Fiel-Gan M, Caimano MJ, Radolf JD, Hawley KL., Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis, PLoS Pathog. 2020 Sep 16;16(9):e1008871. doi: 10.1371/journal.ppat.1008871. eCollection 2020 Sep.
do Nascimento, Naila Cannes; dos Santos, Andrea Pires; Mohallem, Rodrigo; Aryal, Uma K.; Xie, Jun; Cox, Abigail; Sivasankar, M. Preeti, Furosemide-induced systemic dehydration alters the proteome of rabbit vocal folds, Journal of Proteomics. 2021.
Anton-Sales, Irene; Roig-Sanchez, Soledad; Traeger, Kamelia; Weis, Christine; Laromaine, Anna; Turon, Pau; Roig, Anna, In vivo soft tissue reinforcement with bacterial nanocellulose, Biomaterials Science. 2021.
Shangguan AJ, Zhou K, Yang J, Eresen A, Wang B, Sun C, Pan L, Hu S, Khan AT, Mouli SK, Yaghmai V, Zhang Z., Intraprocedural Transcatheter Intraarterial Perfusion (TRIP)-MRI for Evaluation of Irreversible Electroporation Therapy Response in a Rabbit Liver Tumor Model, Clin Exp Gastroenterol. 2020 Nov 6;13:543-553. doi: 10.2147/CEG.S269163. eCollection 2020.
Amemiya K, Zeng X, Bearss JJ, Cote CK, Soffler C, Bernhards RC, Dankmeyer JL, Ribot WJ, Trevino SR, Welkos SL, Worsham PL, Waag DM., Laser Scanning Confocal Microscopy Was Used to Validate the Presence of Burkholderia Pseudomallei or B. Mallei in Formalin-Fixed Paraffin Embedded Tissues, Trop Med Infect Dis. 2020 Apr 29;5(2):65. doi: 10.3390/tropicalmed5020065.
Li XH, Vance GM, Cartwright J, Cao JP, Wilson RA, Castro-Borges W., Mapping the epitopes of Schistosoma japonicum esophageal gland proteins for incorporation into vaccine constructs, PLoS One. 2020 Feb 27;15(2):e0229542. doi: 10.1371/journal.pone.0229542. eCollection 2020.
Pilipenko, Iuliia; Korzhikov-Vlakh, Viktor; Valtari, Annika; Anufrikov, Yurii; Kalinin, Stanislav; Ruponen, Marika; Krasavin, Mikhail; Urtti, Arto; Tennikova, Tatiana, Mucoadhesive properties of nanogels based on stimuli-sensitive glycosaminoglycan-graft-pNIPAAm copolymers, International Journal of Biological Macromolecules. 2021.
Pertici, Irene; Bianchi, Giulio; Bongini, Lorenzo; Cojoc, Dan; Taft, Manuel H.; Manstein, Dietmar J.; Lombardi, Vincenzo; Bianco, Pasquale, Muscle myosin performance measured with a synthetic nanomachine reveals a class-specific Ca2+-sensitivity of the frog myosin II isoform, The Journal of Physiology. 2021.
Okba NMA, Widjaja I, van Dieren B, Aebischer A, van Amerongen G, de Waal L, Stittelaar KJ, Schipper D, Martina B, van den Brand JMA, Beer M, Bosch BJ, Haagmans BL., Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV, Emerg Microbes Infect. 2020 Dec;9(1):1080-1091. doi: 10.1080/22221751.2020.1760735.
Petraitiene R, Petraitis V, Kavaliauskas P, Maung BBW, Khan F, Naing E, Aung T, Zigmantaite V, Grigaleviciute R, Kucinskas A, Stakauskas R, Georgiades BN, Mazur CA, Hayden JA, Satlin MJ, Walsh TJ., Pharmacokinetics and Efficacy of Ceftazidime-Avibactam in the Treatment of Experimental Pneumonia Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae in Persistently Neutropenic Rabbits, Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02157-19. doi: 10.1128/AAC.02157-19. Print 2020 Mar 24.
Amin B, Ford KI, Robinson RAS., Quantitative proteomics to study aging in rabbit liver, Mech Ageing Dev. 2020 Apr;187:111227. doi: 10.1016/j.mad.2020.111227. Epub 2020 Feb 29.
Ton MLH, Keitley D, Theeuwes B, Guibentif C, Ahnfelt-Rønne J, Andreassen TK...Göttgens B., Rabbit development as a model for single cell comparative genomics, bioRxiv 2022.10.06.510971.
Bailey TW, Dos Santos AP, do Nascimento NC, Xie S, Thimmapuram J, Sivasankar MP, Cox A., RNA sequencing identifies transcriptional changes in the rabbit larynx in response to low humidity challenge, BMC Genomics. 2020 Dec 11;21(1):888. doi: 10.1186/s12864-020-07301-7.
Pan L, Sun C, Zhou K, Figini M, Wang B, Shangguan J, Hu S, Yang J, Xing W, Wang J, Velichko Y, Yaghmai V, Zhang Z., Transcatheter Intraarterial Perfusion MRI Approaches to Differentiate Reversibly Electroporated Penumbra From Irreversibly Electroporated Zones in Rabbit Liver, Acad Radiol. 2020 Dec;27(12):1727-1733. doi: 10.1016/j.acra.2020.01.008. Epub 2020 Feb 6.
Cannes do Nascimento N, Dos Santos AP, Sivasankar MP, Cox A., Unraveling the molecular pathobiology of vocal fold systemic dehydration using an in vivo rabbit model, PLoS One. 2020 Jul 31;15(7):e0236348. doi: 10.1371/journal.pone.0236348. eCollection 2020.
Gordon AC, White SB, Gates VL, Procissi D, Harris KR, Yang Y, Zhang Z, Li W, Lyu T, Huang X, Omary RA, Salem R, Lewandowski RJ, Larson AC., Yttrium-90 Radioembolization and Tumor Hypoxia: Gas-challenge BOLD Imaging in the VX2 Rabbit Model of Hepatocellular Carcinoma, Acad Radiol. 2020 Jun 7:S1076-6332(20)30204-X. doi: 10.1016/j.acra.2020.04.012. Online ahead of print.
Cardiovascular
Pertici I, Bianchi G, Bongini L, Lombardi V, Bianco P., A Myosin II-Based Nanomachine Devised for the Study of Ca(2+)-Dependent Mechanisms of Muscle Regulation, Int J Mol Sci. 2020 Oct 6;21(19):7372. doi: 10.3390/ijms21197372.
Saxena P, Myles RC, Smith GL, Workman AJ., Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes., Pflugers Arch. 2022 Dec;474(12):1311-1321. doi: 10.1007/s00424-022-02746-z. Epub 2022 Sep 22.
Streitparth F, Wittgenstein H, Stechele M, Neumann J, Schmidt C, Schnorr J, Hamm B, GĂźnther RW., Biodegradable Polydioxanone Microspheres for Transcatheter Arterial Embolization: Proof of Principle, J Vasc Interv Radiol. 2020 Dec;31(12):2132-2140.e5. doi: 10.1016/j.jvir.2020.07.022. Epub 2020 Nov 5.
Bock C, Vogt B, Mattecka S, Yapici G, Brunner P, Fimpel S, Unger JK, Sheriff A., C-Reactive Protein Causes Blood Pressure Drop in Rabbits and Induces Intracellular Calcium Signaling, Front Immunol. 2020 Aug 28;11:1978. doi: 10.3389/fimmu.2020.01978. eCollection 2020.
Otsomaa L, Levijoki J, Wohlfahrt G, Chapman H, Koivisto AP, Syrjänen K, Koskelainen T, Peltokorpi SE, Finckenberg P, Heikkilä A, Abi-Gerges N, Ghetti A, Miller PE, Page G, Mervaala E, Nagy N, Kohajda Z, Jost N, Viråg L, Varró A, Papp JG., Discovery and characterization of ORM-11372, a novel inhibitor of the sodium-calcium exchanger with positive inotropic activity, Br J Pharmacol. 2020 Dec;177(24):5534-5554. doi: 10.1111/bph.15257. Epub 2020 Nov 10.
Alexander C, Bishop MJ, Gilchrist RJ, MRes BA, Burton FL, Smith GL, Myles RC., Initiation of ventricular arrhythmia in the acquired long QT syndrome, Cardiovasc Res. 2022 Jun 21:cvac103. doi: 10.1093/cvr/cvac103. Online ahead of print.
Rowland EM, Riemer K, Lichtenstein K, Tang MX, Weinberg PD., Non-invasive Assessment by B-Mode Ultrasound of Arterial Pulse Wave Intensity and Its Reduction During Ventricular Dysfunction, Ultrasound Med Biol. 2023 Feb;49(2):473-488. doi: 10.1016/j.ultrasmedbio.2022.09.016. Epub 2022 Nov 2.
Zhang H, Li L, Wu J, Qu HP, Tang YQ, Chen DC., Time of dissociation between microcirculation, macrocirculation, and lactate levels in a rabbit model of early endotoxemic shock, Chin Med J (Engl). 2020 Sep 20;133(18):2153-2160. doi: 10.1097/CM9.0000000000000887.
Dermatology
Hardman CS, Chen YL, Wegrecki M, Ng SW, Murren R, Mangat D, Silva JP, Munro R, Chan WY, O'Dowd V, Doyle C, Mori P, Popplewell A, Rossjohn J, Lightwood D, Ogg GS., D1a promotes systemic manifestations of skin inflammation., Nat Commun. 2022 Dec 7;13(1):7535. doi: 10.1038/s41467-022-35071-1.
General studies
Yan J, Wang B, Riemer K, Hansen-Shearer J, Lerendegui M, Toulemonde M…Tang MX., 3D super-resolution ultrasound with adaptive weight-based beamforming, Electrical Engineering and Systems Science. arXiv:2208.12176
Posobiec LM, Cox EM, Solomon HM, Lewis EM, Wang KF, Stanislaus D, A Probability Analysis of Historical Pregnancy and Fetal Data from Dutch Belted and New Zealand White Rabbit Strains from Embryo-Fetal Development Studies., Birth Defects Res B Dev Reprod Toxicol. 2016 Apr;107(2):76-84
Euler M, Perl T, Eickel I, Dudakova A, Maguilla Rosado E, Drees C, Vautz W, Wieditz J, Meissner K, Kunze-Szikszay N., Blood Culture Headspace Gas Analysis Enables Early Detection of Escherichia coli Bacteremia in an Animal Model of Sepsis., Antibiotics (Basel). 2022 Jul 23;11(8):992. doi: 10.3390/antibiotics11080992.
Bertolino, Nicola; Procissi, Daniele; Disterhoft, John F; Weiss, Craig, Detection of memory- and learning-related brain connectivity changes following trace eyeblink-conditioning using resting-state functional magnetic resonance imaging in the awake rabbit, Journal of Comparative Neurology. 2021.
Riemer K, Toulemonde M, Yan J, Lerendegui M, Stride E, Weinberg PD, Dunsby C, Tang MX, Fast and selective super-resolution ultrasound in vivo with acoustically activated nanodroplets, IEEE Trans Med Imaging. 2022 Nov 18;PP. doi: 10.1109/TMI.2022.3223554. Online ahead of print.
Wang, Dong; Hartman, Robert; Han, Chao; Zhou, Chao-ming; Couch, Brandon; Malkamaki, Matias; Roginskaya, Vera; Van Houten, Bennett; Mullett, Steven J.; Wendell, Stacy G.; Jurczak, Michael J.; Kang, James; Lee, Joon; Sowa, Gwendolyn; Vo, Nam, Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs, Arthritis Research & Therapy. 2021.
Ziejewski MK, Solomon HM, Rendemonti J, Stanislaus D., omparison of a modified mid-coronal sectioning technique and Wilson's technique when conducting eye and brain examinations in rabbit teratology studies., Vaccine. 2015 Jan 9;33(3):430-6.
Immunology
Jones RM Jr, Seo H, Zhang W, Sack DA., A multi-epitope fusion antigen candidate vaccine for Enterotoxigenic Escherichia coli is protective against strain B7A colonization in a rabbit model, PLoS Negl Trop Dis. 2022 Feb 9;16(2):e0010177. doi: 10.1371/journal.pntd.0010177. eCollection 2022 Feb.
Kelly SH, Votaw NL, Cossette BJ, Wu Y, Shetty S, Shores LS, Issah LA, Collier JH., A sublingual nanofiber vaccine to prevent urinary tract infections, Sci Adv. 2022 Nov 25;8(47):eabq4120. doi: 10.1126/sciadv.abq4120. Epub 2022 Nov 23.
Hawksworth D., Advancing Freund's and AddaVax Adjuvant Regimens Using CpG Oligodeoxynucleotides., Monoclon Antib Immunodiagn Immunother. 2018 Nov;37(5):195-199.
Brinkkemper M, Veth TS, Brouwer PJM, Turner H, Poniman M, Burger JA, Bouhuijs JH, Olijhoek W, Bontjer I, Snitselaar JL, Caniels TG, van der Linden CA, Ravichandran R, Villaudy J, van der Velden YU, Sliepen K, van Gils MJ, Ward AB, King NP, Heck AJR, Sanders RW., Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses, iScience. 2022 Dec 22;25(12):105649. doi: 10.1016/j.isci.2022.105649. Epub 2022 Nov 22.
Kurokawa, Natsuki; Lavoie, Pierre-Olivier; D'Aoust, Marc-André; Couture, Manon M. -J.; Dargis, Michčle; Trépanier, Sonia; Hoshino, Shigeki; Koike, Tomohiro; Arai, Masaaki; Tsutsui, Naohisa, Development and characterization of a plant-derived rotavirus-like particle vaccine, Vaccine. 2021.
Henning LN, Carpenter S, Stark GV, Serbina NV, Development of Protective Immunity in New Zealand White Rabbits Challenged with Bacillus anthracis Spores and Treated with Antibiotics and Obiltoxaximab, a Monoclonal Antibody against Protective Antigen, Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01590-17.
Houser KV, Broadbent AJ, Gretebeck L, Vogel L, Lamirande EW, Sutton T, Bock KW, Minai M, Orandle M, Moore IN, Subbarao K., Enhanced inflammation in New Zealand White Rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody., PLoS Pathog. 2017 Aug 17;13(8):e1006565.
Oscherwitz J, Feldman D, Yu F, Cease KB., Epitope-focused peptide immunogens in human use adjuvants protect rabbits from experimental inhalation anthrax., Vaccine. 2015 Jan 9;33(3):430-6.
Panda, Aruna; Tatarov, Ivan; Melton-Celsa, Angela R; Kolappaswamy, Krishnan; Kriel, Edwin H; Petkov, Daniel; Coksaygan, Turhan; Livio, Sofie; McLeod, Charles G; Nataro, James P; OBrien, Alison D; DeTolla, Louis J;, Escherichia coli O157:H7 infection in Dutch belted and New Zealand White Rabbits, Comparative medicine Vol.60, 2010
Del Moral-Sánchez I, Russell RA, Schermer EE, Cottrell CA, Allen JD, Torrents de la Peña A, LaBranche CC, Kumar S, Crispin M, Ward AB, Montefiori DC, Sattentau QJ, Sliepen K, Sanders RW., High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers, NPJ Vaccines. 2022 Feb 28;7(1):27. doi: 10.1038/s41541-022-00446-4.
Oscherwitz J, Cease KB., Identification and validation of a linear protective neutralizing epitope in the β-pore domain of alpha toxin., PLoS One. 2015 Jan 30;10(1):e0116882
Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH, Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection., PLoS One. 2015 Jul 24;10(7):e0130952.
Brouwer, Philip J. M.; Antanasijevic, Aleksandar; de Gast, Marlon; Allen, Joel D.; Bijl, Tom P. L.; Yasmeen, Anila; Ravichandran, Rashmi; Burger, Judith A.; Ozorowski, Gabriel; Torres, Jonathan L.; LaBranche, Celia; Montefiori, David C.; Ringe, Rajesh P.; van Gils, Marit J.; Moore, John P.; Klasse, Per Johan; Crispin, Max; King, Neil P.; Ward, Andrew B.; Sanders, Rogier W., Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles, npj Vaccines. 2021.
Sliepen K, Radić L, Capella-Pujol J, Watanabe Y, Zon I, Chumbe A, Lee WH, de Gast M, Koopsen J, Koekkoek S, Del Moral-Sánchez I, Brouwer PJM, Ravichandran R, Ozorowski G, King NP, Ward AB, van Gils MJ, Crispin M, Schinkel J, Sanders RW., Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate, Nat Commun. 2022 Nov 25;13(1):7271. doi: 10.1038/s41467-022-34961-8.
Townsley S, Mohamed Z, Guo W, McKenna J, Cleveland B, LaBranche C, Beaumont D, Shen X, Yates NL, Pinter A, Tomaras GD, Ferrari G, Montefiori DC, Hu SL., Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization., J Virol. 2016 Sep 12;90(19):8644-60.
Brouwer PJM, Antanasijevic A, Ronk AJ, Müller-Kräuter H, Watanabe Y, Claireaux M, Perrett HR, Bijl TPL, Grobben M, Umotoy JC, Schriek AI, Burger JA, Tejjani K, Lloyd NM, Steijaert TH, van Haaren MM, Sliepen K, de Taeye SW, van Gils MJ, Crispin M, Strecker T, Bukreyev A, Ward AB, Sanders RW., Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection, Cell Host Microbe. 2022 Dec 14;30(12):1759-1772.e12. doi: 10.1016/j.chom.2022.10.018. Epub 2022 Nov 17.
Fairman, Jeff; Agarwal, Paresh; Barbanel, Sandrine; Behrens, Christopher; Berges, Aym; Burky, John; Davey, Peter; Fernsten, Phil; Grainger, Chris; Guo, Sherry; Iki, Sam; Iverson, Mark; Kane, Martin; Kapoor, Neeraj; Marcq, Olivier; Migone, Thi-Sau; Sauer, Paul; Wassil, James, Non-clinical immunological comparison of a Next-Generation 24-valent pneumococcal conjugate vaccine (VAX-24) using site-specific carrier protein conjugation to the current standard of care (PCV13 and PPV23), Vaccine. 2021.
Yamane K, Leung KP., Rabbit M1 and M2 macrophages can be induced by human recombinant GM-CSF and M-CSF., FEBS Open Bio. 2016 Aug 15;6(9):945-53.
Rosner A, Steiner M, Melamed S, Politi B, Vitner E, Tamir H, Achdout H, Cherry L, Avraham R, Yahalom-Ronen Y, Levy H, Beth-Din A, Stein D, Mechaly A, Fisher M, Fatelevich E, Weiss S, Kronfeld N, Madar-Shapiro L, Nyska A, Yitzhaki S, Paran N, Israely T, Marcus H, Madar-Balakirski N., rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits, Arch Toxicol. 2022 Aug;96(8):2329-2339. doi: 10.1007/s00204-022-03302-5. Epub 2022 May 17.
Chen JL, Fries CN, Berendam SJ, Rodgers NS, Roe EF, Wu Y, Li SH, Jain R, Watts B, Eudailey J, Barfield R, Chan C, Moody MA, Saunders KO, Pollara J, Permar SR, Collier JH, Fouda GG., Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation, Sci Adv. 2022 Sep 23;8(38):eabq0273. doi: 10.1126/sciadv.abq0273. Epub 2022 Sep 23.
Zhang YN, Paynter J, Antanasijevic A, Allen JD, Eldad M, Lee YZ…Zhu J., Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates, bioRxiv 2022.07.01.498503.
Sahoo A, Hodge EA, LaBranche CC, Styles TM, Shen X, Cheedarla N, Shiferaw A, Ozorowski G, Lee WH, Ward AB, Tomaras GD, Montefiori DC, Irvine DJ, Lee KK, Amara RR., Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies, Cell Rep. 2022 Mar 1;38(9):110436. doi: 10.1016/j.celrep.2022.110436.
Schorcht A, Cottrell CA, Pugach P, Ringe RP, Han AX, Allen JD, van den Kerkhof TLGM, Seabright GE, Schermer EE, Ketas TJ, Burger JA, van Schooten J, LaBranche CC, Ozorowski G, de Val N, Bader DLV, Schuitemaker H, Russell CA, Montefiori DC, van Gils MJ, Crispin M, Klasse PJ, Ward AB, Moore JP, Sanders RW., The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization, J Virol. 2022 Jan 12;96(1):e0155221. doi: 10.1128/JVI.01552-21. Epub 2021 Oct 20.
Oncology
Müller WEG, Ackermann M, Al-Nawas B, Righesso LAR, Muñoz-Espí R, Tolba E, Neufurth M, Schröder HC, Wang X., Amplified morphogenetic and bone forming activity of amorphous versus crystalline calcium phosphate/polyphosphate, Acta Biomater. 2020 Dec;118:233-247. doi: 10.1016/j.actbio.2020.10.023. Epub 2020 Oct 17.
Fisher, Darrell R., Radiation Safety for Yttrium-90-polymer Composites (RadioGel) in Therapy of Solid Tumors, Health Physics. 2021.
Gordon, Andrew C.; White, Sarah B.; Gates, Vanessa L.; Procissi, Daniel; Harris, Kathleen R.; Yang, Yihe; Zhang, Zhuoli; Li, Weiguo; Lyu, Tianchu; Huang, Xiaoke; Omary, Reed A.; Salem, Riad; Lewandowski, Robert J.; Larson, Andrew C., Yttrium-90 Radioembolization and Tumor Hypoxia: Gas-challenge BOLD Imaging in the VX2 Rabbit Model of Hepatocellular Carcinoma, Academic Radiology. 2021.
Ophthalmology
Zeng Y, Boyd R, Bartoe J, Wiley HE, Marangoni D, Wei LL, Sieving PA., "Para-retinal" Vector Administration into the Deep Vitreous Enhances Retinal Transgene Expression, Mol Ther Methods Clin Dev. 2020 Jun 24;18:422-427. doi: 10.1016/j.omtm.2020.06.015. eCollection 2020 Sep 11.
Bargagna-Mohan P, Schultz G, Rheaume B, Trakhtenberg EF, Robson P, Pal-Ghosh S, Stepp MA, Given KS, Macklin WB, Mohan R., Corneal nonmyelinating Schwann cells illuminated by single-cell transcriptomics and visualized by protein biomarkers, J Neurosci Res. 2020 Nov 16. doi: 10.1002/jnr.24757. Online ahead of print.
Vooturi S, Bourne D, Panda JJ, Choi S, Kim H, Yandrapu SK, Kompella UB., Effect of Particle Size and Viscosity of Suspensions on Topical Ocular Bioavailability of Budesonide, a Corticosteroid, J Ocul Pharmacol Ther. 2020 Jul/Aug;36(6):404-409. doi: 10.1089/jop.2019.0150. Epub 2020 Jul 14.
Sweeney C, Dudhipala N, Thakkar R, Mehraj T, Marathe S, Gul W, ElSohly MA, Murphy B, Majumdar S., Effect of surfactant concentration and sterilization process on intraocular pressure-lowering activity of Î 9-tetrahydrocannabinol-valine-hemisuccinate (NB1111) nanoemulsions, Drug Deliv Transl Res. 2020 Nov 9. doi: 10.1007/s13346-020-00871-9. Online ahead of print.
Petraitiene R, Petraitis V, Maung BBW, Mansbach RS, Hodges MR, Finkelman MA, Shaw KJ, Walsh TJ., Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Non-neutropenic Rabbits, Antimicrob Agents Chemother. 2020 Dec 23:AAC.01795-20. doi: 10.1128/AAC.01795-20. Online ahead of print.
Del Amo EM, Griffiths JR, Klaska IP, Hoke J, White A, Aarons L, Cooper GJS, Bainbridge JWB, Bishop PN, Unwin RD., Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin, Mol Pharm. 2020 Jul 6;17(7):2390-2397. doi: 10.1021/acs.molpharmaceut.0c00151. Epub 2020 Jun 9.
Georgiev GA, Sharifian Gh M, Romano J, Dias Teixeira KL, Struble C, Ryan DS, Sia RK, Kitt JP, Harris JM, Hsu KL, Libby A, Odrich MG, SuĂĄrez T, McKown RL, Laurie GW., Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis, J Biol Chem. 2020 Nov 13:jbc.RA120.015833. doi: 10.1074/jbc.RA120.015833. Online ahead of print.
Schuh JCL., Mucosa-Associated Lymphoid Tissue and Tertiary Lymphoid Structures of the Eye and Ear in Laboratory Animals, Toxicol Pathol. 2020 Nov 28:192623320970448. doi: 10.1177/0192623320970448. Online ahead of print.
Nirmal J, Barathi VA, Dickescheid A, Wey YS, Nirmal S, Raja MM, Venkatraman S, Agrawal R., Potential of subconjunctival aflibercept in treating choroidal neovascularization, Exp Eye Res. 2020 Oct;199:108187. doi: 10.1016/j.exer.2020.108187. Epub 2020 Aug 12.
Laing ST, Tassew N, Tesar D, Wang Y, Crowell SR, Gray J, Kwong M, Loyet KM, Andaya R, Kusi A, Kelley RF., Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins, Toxicol Pathol. 2020 Dec 21:192623320969124. doi: 10.1177/0192623320969124. Online ahead of print.
Kansara VS, Cooper M, Sesenoglu-Laird O, Muya L, Moen R, Ciulla TA., Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits, Transl Vis Sci Technol. 2020 Dec 15;9(13):21. doi: 10.1167/tvst.9.13.21. eCollection 2020 Dec.
Badr MY, Halwani AA, Odunze U, Eskandarpour M, Calder VL, Schätzlein AG, Uchegbu IF., The topical ocular delivery of rapamycin to posterior eye tissues and the suppression of retinal inflammatory disease, Int J Pharm. 2022 Jun 10;621:121755. doi: 10.1016/j.ijpharm.2022.121755. Epub 2022 Apr 18.
Leshno A, Prokai-Tatrai K, Rotenstreich Y, Magid A, Bubis E, Schwartz S, Skaat A, Zloto O, Avni-Zauberman N, Barak A., Topical Estrogen Therapy for Hyperopia Correction in Vivo, Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):55. doi: 10.1167/iovs.61.6.55.
Song H, Zeng Y, Sardar Pasha SPB, Bush RA, Vijayasarathy C, Qian H, Wei L, Wiley HE, Wu Z, Sieving PA., Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration, Transl Vis Sci Technol. 2020 Jun 24;9(7):28. doi: 10.1167/tvst.9.7.28. eCollection 2020 Jun.
Osteology
AlOtaibi, Noura M.; Dunne, Michael; Ayoub, Ashraf F.; Naudi, Kurt B., A novel surgical model for the preclinical assessment of the osseointegration of dental implants: a surgical protocol and pilot study results, Journal of Translational Medicine. 2021.
Coates BA, Silva MJ., An animal trial to study damage and repair in ovariectomized rabbits, J Biomech. 2020 Jul 17;108:109866. doi: 10.1016/j.jbiomech.2020.109866. Epub 2020 Jun 20.
Fabritius M, Al-Munajjed AA, Freytag C, Jülke H, Zehe M, Lemarchand T, Arts JJ, Schumann D, Alt V, Sternberg K., Antimicrobial Silver Multilayer Coating for Prevention of Bacterial Colonization of Orthopedic Implants, Materials (Basel). 2020 Mar 20;13(6):1415. doi: 10.3390/ma13061415.
Tschon M, Brogini S, Parrilli A, Bertoldi S, Silini A, Parolini O, Faré S, Martini L, Veronesi F, Fini M, Giavaresi G., Assessment of the in vivo biofunctionality of a biomimetic hybrid scaffold for osteochondral tissue regeneration, Biotechnol Bioeng. 2021 Jan;118(1):465-480. doi: 10.1002/bit.27584. Epub 2020 Oct 9.
Kilmer CE, Battistoni CM, Cox A, Breur GJ, Panitch A, Liu JC., Collagen Type I and II Blend Hydrogel with Autologous Mesenchymal Stem Cells as a Scaffold for Articular Cartilage Defect Repair, ACS Biomater Sci Eng. 2020 Jun 8;6(6):3464-3476. doi: 10.1021/acsbiomaterials.9b01939. Epub 2020 May 27.
Kieseritzky JV, Alfort H, Granskog V, Hutchinson D, Stenlund P, BogestĂĽl Y, Arner M, HĂĽkansson J, Malkoch M., DendroPrime as an adhesion barrier on fracture fixation plates: an experimental study in rabbits, J Hand Surg Eur Vol. 2020 Sep;45(7):742-747. doi: 10.1177/1753193420932477. Epub 2020 Jun 19.
Han SW, Sawatsky A, Jinha A, Herzog W., Effect of Vastus Medialis Loss on Rabbit Patellofemoral Joint Contact Pressure Distribution, J Appl Biomech. 2020 Aug 25:1-7. doi: 10.1123/jab.2020-0056. Online ahead of print.
Terhune CE, Sylvester AD, Scott JE, Ravosa MJ., Internal architecture of the mandibular condyle of rabbits is related to dietary resistance during growth, J Exp Biol. 2020 Apr 7;223(Pt 7):jeb220988. doi: 10.1242/jeb.220988.
Seol, Dongrim; Choe, Hyeong Hun; Zheng, Hongjun; Brouillette, Marc J; Fredericks, Douglas C; Petersen, Emily B; Song, Ino; Jaidev, Lr; Salem, Aliasger; Martin, James A, Intra-Articular Adeno-Associated Virus-Mediated Proteoglycan 4 Gene Therapy for Preventing Post-Traumatic Osteoarthritis, Human Gene Therapy. 2021.
Baskin, Jonathan Z.; White, Brandon M.; Vasanji, Amit; Love, Thomas E.; Eppell, Steven J., Mandible Biomechanics and Continuously Erupting Teeth: A New Defect Model for Studying Load-Bearing Biomaterials, Biomedicines. 2021.
Lui H, Vaquette C, Denbeigh JM, Bindra R, Kakar S, van Wijnen AJ., Multiphasic scaffold for scapholunate interosseous ligament reconstruction: A study in the rabbit knee, J Orthop Res. 2020 Jun 24:10.1002/jor.24785. doi: 10.1002/jor.24785. Online ahead of print.
Lui, Hayman; Vaquette, Cedryck; Denbeigh, Janet M.; Bindra, Randy; Kakar, Sanjeev; van Wijnen, Andre J., Multiphasic scaffold for scapholunate interosseous ligament reconstruction: A study in the rabbit knee, Journal of Orthopaedic Research. 2021.
Atluri K, Brouillette MJ, Seol D, Khorsand B, Sander E, Salem AK, Fredericks D, Petersen E, Smith S, Fowler TP, Martin JA., Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis, J Orthop Res. 2020 Mar;38(3):629-638. doi: 10.1002/jor.24499. Epub 2019 Nov 11.
Lu Z, Zhou S, Vaida J, Gao G, Stewart A, Parenti J, Yan L, Pei M., Unfavorable Contribution of a Tissue-Engineering Cartilage Graft to Osteochondral Defect Repair in Young Rabbits, Front Cell Dev Biol. 2020 Oct 29;8:595518. doi: 10.3389/fcell.2020.595518. eCollection 2020.
Other
Badr, Moutaz Y.; Abdulrahman, Nurul S.; Schatzlein, Andreas. G.; Uchegbu, Ijeoma. F., A polymeric aqueous tacrolimus formulation for topical ocular delivery, International Journal of Pharmaceutics. 2021.
Bargagna-Mohan, Paola; Schultz, Gwendolyn; Rheaume, Bruce; Trakhtenberg, Ephraim F.; Robson, Paul; Pal-Ghosh, Sonali; Stepp, Mary Ann; Given, Katherine S.; Macklin, Wendy B.; Mohan, Royce, Corneal nonmyelinating Schwann cells illuminated by single-cell transcriptomics and visualized by protein biomarkers, Journal of Neuroscience Research. 2021.
Litvin, Gilad; Klein, Ido; Litvin, Yoav; Klaiman, Guy; Nyska, Abraham, CorNeat KPro: Ocular Implantation Study in Rabbits, Cornea. 2021.
Pattem, J.; Swift, T.; Rimmer, S.; Holmes, T.; MacNeil, S.; Shepherd, J., Development of a novel micro-bead force spectroscopy approach to measure the ability of a thermo-active polymer to remove bacteria from a corneal model, Scientific Reports. 2021.
Shadambikar, Gauri; Marathe, Sushrut; Patil, Akash; Joshi, Rohit; Bandari, Suresh; Majumdar, Soumyajit; Repka, Michael, Novel Application of Hot Melt Extrusion Technology for Preparation and Evaluation of Valacyclovir Hydrochloride Ocular Inserts, AAPS PharmSciTech. 2021.
Sher, Ifat; Goldberg, Zehavit; Bubis, Ettel; Barak, Yoreh; Rotenstreich, Ygal, Suprachoroidal delivery of bevacizumab in rabbit in vivo eyes: Rapid distribution throughout the posterior segment, European Journal of Pharmaceutics and Biopharmaceutics. 2021.
Pharmacology
Morse KW, Moore H, Kumagai H, Hahn W, Koo A, Meyers KN, Bouxsein ML, Brooks DJ, Lanske B, Iyer S, Cunningham M., Abaloparatide Enhances Fusion and Bone Formation in a Rabbit Spinal Arthrodesis Model, Spine (Phila Pa 1976). 2022 Nov 15;47(22):1607-1612. doi: 10.1097/BRS.0000000000004452. Epub 2022 Aug 9.
Nagy, C F; Mondick, J; Serbina, N; Casey, L S; Carpenter, S E; French, J; Guttendorf, R;, Animal-to-Human Dose Translation of Obiltoxaximab for Treatment of Inhalational Anthrax Under the US FDA Animal Rule., Clinical and translational science Vol.10, 2017
Hild, S A; Reel, J R; Hoffman, L H; Blye, R P;, CDB-2914: anti-progestational/anti-glucocorticoid profile and post-coital anti-fertility activity in rats and rabbits, Human reproduction (Oxford, England) Vol.15, 2000
Petraitis, Vidmantas; Petraitiene, Ruta; Naing, Ethan; Aung, Thein; Thi, Wai Phyo; Kavaliauskas, Povilas; Win Maung, Bo Bo; Michel, Adam O; Ricart Arbona, Rodolfo J; DeRyke, Andrew C; Culshaw, Darren L; Nicolau, David P; Satlin, Michael J; Walsh, Thomas J;, Ceftolozane-Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains with Genetically Defined Mechanisms of Resistance., Antimicrobial agents and chemotherapy Vol.63, 2019
Comer, Jason E; Ray, Bryan D; Henning, Lisa N; Stark, Gregory V; Barnewall, Roy E; Mott, Jason M; Meister, Gabriel T;, Characterization of a therapeutic model of inhalational anthrax using an increase in body temperature in New Zealand White Rabbits as a trigger for treatment. Clinical and vaccine immunology, CVI Vol.19, 2012
Kammanadiminti, Srinivas; Patnaikuni, Ravi Kumar; Comer, Jason; Meister, Gabriel; Sinclair, Chris; Kodihalli, Shantha;, Combination therapy with antibiotics and anthrax immune globulin intravenous (AIGIV) is potentially more effective than antibiotics alone in rabbit model of inhalational anthrax., PloS one Vol.9, 2014
Boyer DD, Ko YP, Podos SD, Cartwright ME, Gao X, Wiles JA, Huang M., Danicopan, an Oral Complement Factor D Inhibitor, Exhibits High and Sustained Exposure in Ocular Tissues in Preclinical Studies, Transl Vis Sci Technol. 2022 Oct 3;11(10):37. doi: 10.1167/tvst.11.10.37.
Rochani A, Agrahari V, Chandra N, Singh ON, McCormick TJ, Doncel GF, Clark MR, Kaushal G., Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives, Polymers (Basel). 2022 Apr 23;14(9):1728. doi: 10.3390/polym14091728.
Schoenberg, Evan D; Blake, Diane A; Swann, F Beau; Parlin, Andrew W; Zurakowski, David; Margo, Curtis E; Ponnusamy, Thiruselvam; John, Vijay T; Ayyala, Ramesh S;, Effect of Two Novel Sustained-Release Drug Delivery Systems on Bleb Fibrosis: An In Vivo Glaucoma Drainage Device Study in a Rabbit Model., Translational vision science & technology Vol.4, 2015
Grossi, Irma M; Foster, Scott A; Gainey, Melicia R; Krile, Robert T; Dunn, John A; Brundage, Thomas; Khouri, Jody M;, Efficacy of delayed brincidofovir treatment against a lethal rabbitpox virus challenge in New Zealand White Rabbits., Antiviral research Vol.143, 2017
Yamamoto, Brent J; Shadiack, Annette M; Carpenter, Sarah; Sanford, Daniel; Henning, Lisa N; OConnor, Edward; Gonzales, Nestor; Mondick, John; French, Jonathan; Stark, Gregory V; Fisher, Alan C; Casey, Leslie S; Serbina, Natalya V, Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity., Antimicrobial agents and chemotherapy Vol.60, 2016
Huang DB, Brothers KM, Mandell JB, Taguchi M, Alexander PG, Parker DM, Shinabarger D, Pillar C, Morrissey I, Hawser S, Ghahramani P, Dobbins D, Pachuda N, Montelaro R, Steckbeck JD, Urish KL., Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class, PLoS One. 2022 Sep 16;17(9):e0274815. doi: 10.1371/journal.pone.0274815. eCollection 2022.
Hardwick RN, Brassil P, Badagnani I, Perkins K, Obedencio GP, Kim AS, Conner MW, Bourdet DL, Harstad EB., Gut-Selective Design of Orally Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species, Toxicol Sci. 2022 Mar 28;186(2):323-337. doi: 10.1093/toxsci/kfac002.
Martchenko Shilman, Mikhail; Bartolo, Gloria; Alameh, Saleem; Peterson, Johnny W.; Lawrence, William S.; Peel, Jennifer E.; Sivasubramani, Satheesh K.; Beasley, David W. C.; Cote, Christopher K.; Demons, Samandra T.; Halasahoris, Stephanie A.; Miller, Lynda L.; Klimko, Christopher P.; Shoe, Jennifer L.; Fetterer, David P.; McComb, Ryan; Ho, Chi-Lee C.; Bradley, Kenneth A.; Hartmann, Stella; Cheng, Luisa W.; Chugunova, Marina; Kao, Chiu-Yen; Tran, Jennifer K.; Derbedrossian, Aram; Zilbermintz, Leeor; Amali-Adekwu, Emiene; Levitin, Anastasia; West, Joel, In Vivo Activity of Repurposed Amodiaquine as a Host-Targeting Therapy for the Treatment of Anthrax, ACS Infectious Diseases. 2021.
Gutting, Bradford W; Nichols, Tonya L; Channel, Stephen R; Gearhart, Jeffery M; Andrews, George A; Berger, Alan E; Mackie, Ryan S; Watson, Brent J; Taft, Sarah C; Overheim, Katie A; Sherwood, Robert L;, Inhalational anthrax (Ames aerosol) in naĂŻve and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia, Frontiers in cellular and infection microbiology Vol.2, 2012
Kim, Kyong Ho; Cao, Jiafu; Yoo, Jin-Wook; Yoon, In-Soo; Jung, Jae Woo; Lee, Ji Eun; Byon, Ik Soo;, Intraocular Pharmacokinetics of Povidone-Iodine and Its Effects on Experimental Staphylococcus epidermidis Endophthalmitis, Investigative ophthalmology & visual science Vol.56, 2015
Pei M, Pei YA, Zhou S, Mikaeiliagah E, Erickson C, Giertych B, Akhter H, Wang L, Stewart A, Parenti J, Wang B, Wen S, Sim S, Quenneville E, Hansen KC, Frisch S, Hu G., Matrix from urine stem cells boosts tissue-specific stem cell mediated functional cartilage reconstruction, Bioact Mater. 2022 Nov 25;23:353-367. doi: 10.1016/j.bioactmat.2022.11.012. eCollection 2023 May.
Martinez-Hernandez E, Kanaporis G, Blatter LA., Mechanism of carvedilol induced action potential and calcium alternans, Channels (Austin). 2022 Dec;16(1):97-112. doi: 10.1080/19336950.2022.2055521.
Ibarra, R; Dazard, J-E; Sandlers, Y; Rehman, F; Abbas, R; Kombu, R; Zhang, G-F; Brunengraber, H; Sanabria, J;, Metabolomic Analysis of Liver Tissue from the VX2 Rabbit Model of Secondary Liver Tumors., HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Vol.2014, 2014
Wong PC, Crain EJ, Bozarth JM, Wu Y, Dilger AK, Wexler RR, Ewing WR, Gordon D, Luettgen JM., Milvexian, an orally bioavailable, small-molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits, J Thromb Haemost. 2022 Feb;20(2):399-408. doi: 10.1111/jth.15588. Epub 2021 Nov 24.
Verhoeven, Rozemarijn S; Garcia, Andres; Robeson, RiLee; Gilger, Brian C; Culp, David; Struble, Craig; Hamm, Lee; Navratil, Tomas; Yerxa, Benjamin;, Nonclinical Development of ENV905 (Difluprednate) Ophthalmic Implant for the Treatment of Inflammation and Pain Associated with Ocular Surgery., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.34,
Yamamoto, Brent J; Shadiack, Annette M; Carpenter, Sarah; Sanford, Daniel; Henning, Lisa N; Gonzales, Nestor; OConnor, Edward; Casey, Leslie S; Serbina, Natalya V;, Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax., Antimicrobial agents and chemotherapy Vol.60, 2016
Jimenez J, Resnick JL, Chaudhry AB, Gertsman I, Nischal KK, DiLeo MV., Ocular biodistribution of cysteamine delivered by a sustained release microsphere/thermoresponsive gel eyedrop, Int J Pharm. 2022 Aug 25;624:121992. doi: 10.1016/j.ijpharm.2022.121992. Epub 2022 Jul 7.
Shen, Jie; Goodkin, Margot L; Tong, Warren; Attar, Mayssa;, Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications., Clinical ophthalmology (Auckland, N.Z.) Vol.11, 2017
Iyer, Ganesh R; Cason, Marita M; Womble, Scott W; Li, Guangming; Chastain, James E;, Ocular pharmacokinetics comparison between 0.2% olopatadine and 0.77% olopatadine hydrochloride ophthalmic solutions administered to male New Zealand White Rabbits., ournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.31, 2015
Coursey, Terry G; Wassel, Ronald A; Quiambao, Alexander B; Farjo, Rafal A;, Once-Daily Cyclosporine-A-MiDROPS for Treatment of Dry Eye Disease., Translational vision science & technology Vol.7, 2018
Farrington N, McEntee L, Johnson A, Unsworth J, Darlow C, Jimenez-Valverde A, Hornik C, Greenberg R, Schwartz J, Das S, Hope W. , Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance, Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0218121. doi: 10.1128/aac.02181-21. Epub 2022 Mar 22.
Totten KMC, Cunningham SA, Gades NM, Etzioni A, Patel R., Pharmacokinetic Assessment of Staphylococcal Phage K Following Parenteral and Intra-articular Administration in Rabbits, Front Pharmacol. 2022 May 20;13:840165. doi: 10.3389/fphar.2022.840165. eCollection 2022.
Petraitis, Vidmantas; Petraitiene, Ruta; Maung, Bo Bo W; Khan, Farehin; Alisauskaite, Ieva; Olesky, Melanie; Newman, Joseph; Mutlib, Abdul; Niu, Xiaoyun; Satlin, Michael; Singh, Ravi S; Derendorf, Harmut; Walsh, Thomas J;, Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits, Antimicrobial agents and chemotherapy Vol.62, 2018
Slay RM, Cook R, Hendricks K, Boucher D, Merchlinsky M., Pre- and Postlicensure Animal Efficacy Studies Comparing Anthrax Antitoxins, Clin Infect Dis. 2022 Oct 17;75(Suppl 3):S441-S450. doi: 10.1093/cid/ciac593.
Perry, Mark R; Warren, Richard; Merchlinsky, Michael; Houchens, Christopher; Rogers, James V;, Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule, Frontiers in cellular and infection microbiology Vol.8, 2018
Dolivo D, Rodrigues A, Sun L, Hou C, Li Y, Chung E, Leung K, Galiano R, Mustoe T, Hong SJ., Simvastatin cream alleviates dermal fibrosis in a rabbit ear hypertrophic scar model, J Cosmet Dermatol. 2022 Jun 4. doi: 10.1111/jocd.15142. Online ahead of print.
Wink, Jason D; Gerety, Patrick A; Sherif, Rami D; Lim, Youngshin; Clarke, Nadya A; Rajapakse, Chamith S; Nah, Hyun-Duck; Taylor, Jesse A, Sustained delivery of rhBMP-2 by means of poly(lactic-co-glycolic acid) microspheres: cranial bone regeneration without heterotopic ossification or craniosynostosis., Plastic and reconstructive surgery Vol.134, 2014
Trost, Lawrence C; Rose, Michelle L; Khouri, Jody; Keilholz, Laurie; Long, James; Godin, Stephen J; Foster, Scott A;, The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease., Antiviral research Vol.117, 2015
Smith, Sara M.; Salmon, Jacklyn H.; Abbaraju, Santhi; Amin, Rasid; Gilger, Brian C., Tolerability, pharmacokinetics, and pharmacodynamics of a brinzolamide episcleral sustained release implant in normotensive New Zealand White Rabbits, Journal of Drug Delivery Science and Technology. 2021.
Schopf, Lisa R; Popov, Alexey M; Enlow, Elizabeth M; Bourassa, James L; Ong, Winston Z; Nowak, Pawel; Chen, Hongming;, Topical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles., Translational vision science & technology Vol.4, 2015
Chollet, Janet; Mermelstein, Fred; Rocamboli, Stephen C; Friend, David R;, Vaginal tamoxifen for treatment of vulvar and vaginal atrophy: Pharmacokinetics and local tolerance in a rabbit model over 28 days., International journal of pharmaceutics Vol.570, 2019
Surgical
Jabbour, Richard J.; Owen, Thomas J.; Pandey, Pragati; Reinsch, Marina; Wang, Brian; King, Oisín; Couch, Liam Steven; Pantou, Dafni; Pitcher, David S.; Chowdhury, Rasheda A.; Pitoulis, Fotios G.; Handa, Balvinder S.; Kit-Anan, Worrapong; Perbellini, Filippo; Myles, Rachel C.; Stuckey, Daniel J.; Dunne, Michael; Shanmuganathan, Mayooran; Peters, Nicholas S.; Ng, Fu Siong; Weinberger, Florian; Terracciano, Cesare M.; Smith, Godfrey L.; Eschenhagen, Thomas; Harding, Sian E., In vivo grafting of large engineered heart tissue patches for cardiac repair, JCI Insight. 2021.
D'Cruz, Roshan J.; Sampson, Valerie B.; Askinas, Carly A.; Scott, Rebecca A.; Robinson, Karyn G.; Beaty, Claude A.; Hesek, Anne M.; Akins, Robert E., Neointimal hyperplasia after carotid transection and anastomosis surgery is associated with degradation of decorin and platelet-derived growth factor signaling, JVS: Vascular Science. 2021.
Lawrence WS, Peel JE, Sivasubramani SK, Baze WB, Whorton EB, Beasley DWC, Comer JE, Hughes DE, Ling LL, Peterson JW., Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model, Pathogens. 2020 Sep 22;9(9):773. doi: 10.3390/pathogens9090773.
Teratology
Hilbish KG, Martin JA, Stauber AJ, Edwards TL, Breslin WJ., Assessment of embryo-fetal toxicity in rats and rabbits., Birth Defects Res B Dev Reprod Toxicol. 2016 Aug;107(4-5):174-184
Breslin WJ, Hilbish KG, Page TJ, Coutant DE., Assessment of fetal exposure risk following seminal excretion of a therapeutic IgG4 (T-IgG4) monoclonal antibody using a rabbit model., Reprod Toxicol. 2014 Sep;48:124-31
Marshall VA, Johnson KJ, Moore NP, Rasoulpour RJ, Tornesi B, Carney EW., Comparative response of rat and rabbit conceptuses in vitro to inhibitors of histiotrophic nutrition, Birth Defects Res B Dev Reprod Toxicol. 2015 Feb;104(1):1-10
Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Edwards TL., Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody., Birth Defects Res B Dev Reprod Toxicol. 2015 Jun;104(3):117-28
Catlin N, Waidyanatha S, Mylchreest E, Miller-Pinsler L, Cunny H, Foster P, Sutherland V, McIntyre B., Embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit., Birth Defects Res. 2018 Jun 1;110(10):883-896
Hui JY, Hoffmann M, Kumar G., Embryo-fetal exposure and developmental outcome of thalidomide following oral and intravaginal administration to pregnant rabbits., Reprod Toxicol. 2014 Sep;48:115-23.
Crute CE, Hall SM, Landon CD, Garner A, Everitt JI, Zhang S, Blake B, Olofsson D, Chen H, Murphy SK, Stapleton HM, Feng L., Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model, Sci Total Environ. 2022 Sep 10;838(Pt 4):156499. doi: 10.1016/j.scitotenv.2022.156499. Epub 2022 Jun 6.
Bugaj JE, Dorshow RB., Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate, Int J Toxicol. 2022 Sep-Oct;41(5):380-388. doi: 10.1177/10915818221111331. Epub 2022 Jun 27.
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