CFTR knockout rats
Related publications
Cystic Fibrosis
Keith JD, Henderson AG, Fernandez-Petty CM, Davis JM, Oden AM, Birket SE., Muc5b Contributes to Mucus Abnormality in Rat Models of Cystic Fibrosis., Front Physiol. 2022 Apr 28;13:884166. doi: 10.3389/fphys.2022.884166. eCollection 2022.
Lung disease
Tuggle KL, Birket SE, Cui X, Hong J, Warren J, Reid L, Chambers A, Ji D, Gamber K, Chu KK, Tearney G, Tang LP, Fortenberry JA, Du M, Cadillac JM, Bedwell DM, Rowe SM, Sorscher EJ, Fanucchi MV., Characterization of Defects in Ion Transport and Tissue Development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Knockout Rats., PLoS ONE. 2014 Mar 7; 9(3): e91253
Tipirneni KE, Cho DY, Skinner DF, Zhang S, Mackey C, Lim DJ, Woodworth BA., Characterization of primary rat nasal epithelial cultures in CFTR knockout rats as a model for CF sinus disease., Laryngoscope. 2017 Nov;127(11):E384-E391.
Birket SE, Davis JM, Fernandez CM, Tuggle KL, Oden AM, Chu KK, Tearney GJ, Fanucchi MV, Sorscher EJ, Rowe SM., Development of an airway mucus defect in the cystic fibrosis rat., JCI Insight. 2018 Jan 11;3(1). pii: 97199
Stalvey MS, Havasi V, Tuggle KL, Wang D, Birket S, Rowe SM, Sorscher EJ., Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat., PLoS One. 2017 Nov 30;12(11):e0188497.
Grayson J, Tipirneni KE, Skinner DF, Fort M, Cho DY, Zhang S, Prince AC, Lim DJ, Mackey C, Woodworth BA., Sinus hypoplasia in the cystic fibrosis rat resolves in the absence of chronic infection., Int Forum Allergy Rhinol. 2017 Sep;7(9):904-909
