Athymic nude mice

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Autoimmune disease

Kalliokoski, S., Caja, S., Frias, R., Laurila, K., Koskinen, O., Niemela, O., . . . Lindfors, K. (2015), Injection of celiac disease patient sera or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease., Journal of Molecular Medicine (Berlin, Germany), 93(1), 51-62. doi:10.1007/s00109-014-1204-8 [doi]

Gene therapy

Qiu M, Li G, Wang P, Li X, Lai F, Luo R, Liu B, Lin J., aarF domain containing kinase 5 gene promotes invasion and migration of lung cancer cells through ADCK5-SOX9-PTTG1 pathway, Exp Cell Res. 2020 Jul 1;392(1):112002. doi: 10.1016/j.yexcr.2020.112002. Epub 2020 Apr 8.

Lampe, J., Bossow, S., Weiland, T., Smirnow, I., Lehmann, R., Neubert, W., . . . Lauer, U. M. (2013)., An armed oncolytic measles vaccine virus eliminates human hepatoma cells independently of apoptosis., Gene Therapy, 20(11), 1033-1041. doi:10.1038/gt.2013.28 [doi]

Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M., Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers, Cancers (Basel). 2020 Sep 29;12(10):2795. doi: 10.3390/cancers12102795.

Feichtinger, G. A., Hacobian, A., Hofmann, A. T., Wassermann, K., Zimmermann, A., van Griensven, M., & Redl, H. (2014)., Constitutive and inducible co-expression systems for non-viral osteoinductive gene therapy., European Cells & Materials, 27, 166-84; discussion 184. doi:vol027a13 [pii]

McCarthy GA, Di Niro R, Finan JM, Jain A, Guo Y, Wyatt CR, Guimaraes AR, Waugh TA, Keith D, Morgan TK, Sears RC, Brody JR., Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity., NAR Cancer. 2023 Apr 19;5(2):zcad016. doi: 10.1093/narcan/zcad016. eCollection 2023 Jun.

Gentschev, I., Muller, M., Adelfinger, M., Weibel, S., Grummt, F., Zimmermann, M., . . . Szalay, A. A. (2011)., Efficient colonization and therapy of human hepatocellular carcinoma (HCC) using the oncolytic vaccinia virus strain GLV-1h68., PloS One, 6(7), e22069. doi:10.1371/journal.pone.0022069 [doi]

Arruabarrena-Aristorena A, Maag JLV, Kittane S, Cai Y, Karthaus WR, Ladewig E, Park J, Kannan S, Ferrando L, Cocco E, Ho SY, Tan DS, Sallaku M, Wu F, Acevedo B, Selenica P, Ross DS, Witkin M, Sawyers CL, Reis-Filho JS, Verma CS, Jauch R, Koche R, Baselga J, Razavi P, Toska E, Scaltriti M., FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer, Cancer Cell. 2020 Oct 12;38(4):534-550.e9. doi: 10.1016/j.ccell.2020.08.003. Epub 2020 Sep 3.

Yu, L., Liang, Y., Cao, X., Wang, X., Gao, H., Lin, S. Y., . . . Li, K. (2017), Identification of MYST3 as a novel epigenetic activator of ERalpha frequently amplified in breast cancer., Oncogene, 36(20), 2910-2918. doi:10.1038/onc.2016.433 [doi]

Unzu, C., Melero, I., Morales-Kastresana, A., Sampedro, A., Serrano-Mendioroz, I., Azpilikueta, A., . . . Fontanellas, A. (2014), Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus, PloS One, 9(1), e85432. doi:10.1371/journal.pone.0085432 [doi]

Dowaidar, M., Abdelhamid, H. N., Hallbrink, M., Freimann, K., Kurrikoff, K., Zou, X., & Langel, U. (2017)., Magnetic nanoparticle assisted self-assembly of cell penetrating peptides-oligonucleotides complexes for gene delivery, Scientific Reports, 7(1), 9159-017-09803-z. doi:10.1038/s41598-017-09803-z [doi]

Dinami R, Pompili L, Petti E, Porru M, D'Angelo C, Di Vito S, Rizzo A, Campani V, De Rosa G, Bruna A, Serra V, Mano M, Giacca M, Leonetti C, Ciliberto G, Tarsounas M, Stoppacciaro A, Schoeftner S, Biroccio A., MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer., EMBO Mol Med. 2023 Jan 11;15(1):e16033. doi: 10.15252/emmm.202216033. Epub 2022 Nov 25.

Kim SS, Doherty C, Moghe M, Rait A, Pirollo KF, Harford JB, Chang EH., Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity, Cancers (Basel). 2022 Oct 18;14(20):5092. doi: 10.3390/cancers14205092.

Ady, J. W., Johnsen, C., Mojica, K., Heffner, J., Love, D., Pugalenthi, A., . . . Fong, Y. (2015)., Oncolytic gene therapy with recombinant vaccinia strain GLV-2b372 efficiently kills hepatocellular carcinoma., Surgery, 158(2), 331-338. doi:10.1016/j.surg.2015.03.044 [doi]

Veiman, K. L., Kunnapuu, K., Lehto, T., Kiisholts, K., Parn, K., Langel, U., & Kurrikoff, K. (2015)., PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo., Journal of Controlled Release : Official Journal of the Controlled Release Society, 209, 238-247. doi:10.1016/j.jconrel.2015.04.038 [doi]

Croessmann, S., Wong, H. Y., Zabransky, D. J., Chu, D., Rosen, D. M., Cidado, J., . . . Park, B. H. (2017)., PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity., Breast Cancer Research and Treatment, 162(3), 451-464. doi:10.1007/s10549-017-4147-2 [doi]

Hollevoet, K., De Smidt, E., Geukens, N., & Declerck, P. (2018), Prolonged in vivo expression and anti-tumor response of DNA-based anti-HER2 antibodies, Oncotarget, 9(17), 13623-13636. doi:10.18632/oncotarget.24426 [doi]

Kaliberov, S. A., Kaliberova, L. N., Yan, H., Kapoor, V., & Hallahan, D. E. (2016)., Retargeted adenoviruses for radiation-guided gene delivery., Cancer Gene Therapy, 23(9), 303-314. doi:10.1038/cgt.2016.32 [doi]

Shapira, S., Shapira, A., Kazanov, D., Hevroni, G., Kraus, S., & Arber, N. (2017)., Selective eradication of cancer cells by delivery of adenovirus-based toxins., Oncotarget, 8(24), 38581-38591. doi:10.18632/oncotarget.16934 [doi]

Anders, N. M., Liu, J., Wanjiku, T., Giovinazzo, H., Zhou, J., Vaghasia, A., . . . Rudek, M. A. (2016)., Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors, Journal of Chromatography.B, Analytical Technologies in the Biomedical and Life Sciences, 1022, 38-45. doi:S1570-0232(16)30178-7 [pii]

Feichtinger, G. A., Hofmann, A. T., Slezak, P., Schuetzenberger, S., Kaipel, M., Schwartz, E., . . . Redl, H. (2014)., Sonoporation increases therapeutic efficacy of inducible and constitutive BMP2/7 in vivo gene delivery., Human Gene Therapy Methods, 25(1), 57-71. doi:10.1089/hgtb.2013.113 [doi]

Abel, T., El Filali, E., Waern, J., Schneider, I. C., Yuan, Q., Munch, R. C., . . . Buchholz, C. J. (2013)., Specific gene delivery to liver sinusoidal and artery endothelial cells, Blood, 122(12), 2030-2038. doi:10.1182/blood-2012-11-468579 [doi]

Hou R, Yu Y, Sluter MN, Li L, Hao J, Fang J, Yang J, Jiang J., Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma, Cell Rep. 2022 Jun 21;39(12):111000. doi: 10.1016/j.celrep.2022.111000.

Chatterjee S, Naidu GS, Hazan-Halevy I, Grobe H, Ezra A, Sharma P, Goldsmith M, Ramishetti S, Sprinzak D, Zaidel-Bar R, Peer D., Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells., Sci Adv. 2023 Apr 5;9(14):eade4800. doi: 10.1126/sciadv.ade4800. Epub 2023 Apr 5.

Presutti, D., Ceccarelli, M., Micheli, L., Papoff, G., Santini, S., Samperna, S., . . . Tirone, F. (2018)., Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model., PloS One, 13(3), e0194206. doi:10.1371/journal.pone.0194206 [doi]

Nomikou, N., Feichtinger, G. A., Saha, S., Nuernberger, S., Heimel, P., Redl, H., & McHale, A. P. (2018)., Ultrasound-responsive gene-activated matrices for osteogenic gene therapy using matrix-assisted sonoporation., Journal of Tissue Engineering and Regenerative Medicine, 12(1), e250-e260. doi:10.1002/term.2406 [doi]

General studies

Choi YH, Zhang C, Liu Z, Tu MJ, Yu AX, Yu AM., A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism, J Pharmacol Exp Ther. 2021 Jun;377(3):305-315. doi: 10.1124/jpet.121.000584. Epub 2021 Mar 12.

Landgraf, L., Christner, C., Storck, W., Schick, I., Krumbein, I., Dahring, H., . . . Hilger, I. (2015), A plasma protein corona enhances the biocompatibility of Au@Fe3O4 janus particles, Biomaterials, 68, 77-88. doi:10.1016/j.biomaterials.2015.07.049 [doi]

Cook Sangar ML, Girard EJ, Hopping G, Yin C, Pakiam F, Brusniak MY, Nguyen E, Ruff R, Gewe MM, Byrnes-Blake K, Nairn NW, Miller DM, Mehlin C, Strand AD, Mhyre AJ, Correnti CE, Strong RK, Simon JA, Olson JM., A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure, Sci Transl Med. 2020 Mar 4;12(533):eaay1041. doi: 10.1126/scitranslmed.aay1041.

Crook ZR, Girard E, Sevilla GP, Merrill M, Friend D, Rupert PB, Pakiam F, Nguyen E, Yin C, Ruff RO, Hopping G, Strand AD, Finton KAK, Coxon M, Mhyre AJ, Strong RK, Olson JM., A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules, J Mol Biol. 2020 Jun 26;432(14):3989-4009. doi: 10.1016/j.jmb.2020.04.002. Epub 2020 Apr 15.

Joshi S, Montes de Oca I, Maghrabi A, Lopez-Yang C, Quiroz-Olvera J, Garcia CA, Jarajapu YPR., ACE2 gene transfer ameliorates vasoreparative dysfunction in CD34+ cells derived from diabetic older adults, Clin Sci (Lond). 2021 Jan 29;135(2):367-385. doi: 10.1042/CS20201133.

Crum RJ, Capella-Monsonís H, Chang J, Dewey MJ, Kolich BD, Hall KT, El-Mossier SO, Nascari DG, Hussey GS, Badylak SF., Biocompatibility and biodistribution of matrix-bound nanovesicles in vitro and in vivo, Acta Biomater. 2023 Jan 1;155:113-122. doi: 10.1016/j.actbio.2022.11.026. Epub 2022 Nov 22.

Talele S, Zhang W, Chen J, Gupta SK, Burgenske DM, Sarkaria JN, Elmquist WF., Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain Tumors, J Pharmacol Exp Ther. 2022 Oct;383(1):91-102. doi: 10.1124/jpet.122.001230. Epub 2022 Aug 5.

Das, S., Haedicke, K., & Grimm, J. (2018)., Cerenkov-activated sticky tag for in vivo fluorescence imaging., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 59(1), 58-65. doi:10.2967/jnumed.117.198549 [doi]

Gaffron F, Tilch A, Grüttner C, Kowalski A, Kramer M, Teichgräber U, Hilger AI., Challenges in Tracking of Fluorochrome-Labelled Nanoparticles in Mice via Whole Body NIRF Imaging, Nanomaterials (Basel). 2020 Mar 24;10(3):596. doi: 10.3390/nano10030596.

Rahman, C. V., Ben-David, D., Dhillon, A., Kuhn, G., Gould, T. W., Muller, R., . . . Livne, E. (2014)., Controlled release of BMP-2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model., Journal of Tissue Engineering and Regenerative Medicine, 8(1), 59-66. doi:10.1002/term.1497 [doi]

Deng H, Qiao H, Dai Q, Ma C., Deep learning in photoacoustic imaging: a review, J Biomed Opt. 2021 Apr;26(4):040901. doi: 10.1117/1.JBO.26.4.040901.

Andleeb F, Katta N, Gruslova A, Muralidharan B, Estrada A, McElroy AB, Ullah H, Brenner AJ, Milner TE., Differentiation of Brain Tumor Microvasculature From Normal Vessels Using Optical Coherence Angiography, Lasers Surg Med. 2021 Jun 15. doi: 10.1002/lsm.23446. Online ahead of print.

Altshuler A, Amitai-Lange A, Tarazi N, Dey S, Strinkovsky L, Hadad-Porat S, Bhattacharya S, Nasser W, Imeri J, Ben-David G, Abboud-Jarrous G, Tiosano B, Berkowitz E, Karin N, Savir Y, Shalom-Feuerstein R., Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing, Cell Stem Cell. 2021 Jul 1;28(7):1248-1261.e8. doi: 10.1016/j.stem.2021.04.003. Epub 2021 May 12.

Netser S, Meyer A, Magalnik H, Zylbertal A, de la Zerda SH, Briller M, Bizer A, Grinevich V, Wagner S., Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains, Nat Commun. 2020 Nov 20;11(1):5908. doi: 10.1038/s41467-020-19569-0.

Manuel R, Lima MS, Dilly S, Daunay S, Abbe P, Pramil E, Solier S, Guillaumond F, Tubiana SS, Escargueil A, Pęgas Henriques JA, Ferrand N, Erdelmeier I, Boucher JL, Bertho G, Agranat I, Rocchi S, Sabbah M, Slama Schwok A., Distinction between 2'- and 3'-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration, Antioxidants (Basel). 2021 May 4;10(5):723. doi: 10.3390/antiox10050723.

Robin J, Ozbek A, Reiss M, Dean-Ben XL, Razansky D., Dual-Mode Volumetric Photoacoustic and Contrast Enhanced Ultrasound Imaging with Spherical Matrix Arrays, IEEE Trans Med Imaging. 2021 Nov 4;PP. doi: 10.1109/TMI.2021.3125398. Online ahead of print.

Kim, H. J., Park, S. S., Oh, S. Y., Kim, H., Kweon, O. K., Woo, H. M., & Kim, W. H. (2012), Effect of acellular dermal matrix as a delivery carrier of adipose-derived mesenchymal stem cells on bone regeneration., Journal of Biomedical Materials Research.Part B, Applied Biomaterials, 100(6), 1645-1653. doi:10.1002/jbm.b.32733 [doi]

Frees, S., Bidnur, S., Metcalfe, M., Raven, P., Chavez-Munoz, C., Moskalev, I., . . . So, A. (2016), Effect of contrast media on urinary cytopathology specimens., Canadian Urological Association Journal = Journal De l'Association Des Urologues Du Canada, 10(7-8), 228-233. doi:10.5489/cuaj.3874 [doi]

Floyd RJ, Ricart Arbona RJ, Carrasco SE, Lipman NS., Examination of Horizontal Transmission of Nippostrongylus brasiliensis in Mice to Assess Biosecurity Risks., J Am Assoc Lab Anim Sci. 2023 May 1;62(3):243-253. doi: 10.30802/AALAS-JAALAS-23-000004. Epub 2023 May 1.

Luengo Y, Díaz-Riascos ZV, García-Soriano D, Teran FJ, Artés-Ibáñez EJ, Ibarrola O, Somoza Á, Miranda R, Schwartz S Jr, Abasolo I, Salas G., Fine Control of In Vivo Magnetic Hyperthermia Using Iron Oxide Nanoparticles with Different Coatings and Degree of Aggregation, Pharmaceutics. 2022 Jul 22;14(8):1526. doi: 10.3390/pharmaceutics14081526.

Muñoz, Juan J; Tobajas, Esther; Juara, Sonia; Montero, Sara; Zapata, Agustín G;, FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis. Histochemistry and cell biology Vol.152, 2019, Histochemistry and cell biology Vol.152, 2019

van Rijn, S., Nilsson, J., Noske, D. P., Vandertop, W. P., Tannous, B. A., & Wurdinger, T. (2013), Functional multiplex reporter assay using tagged gaussia luciferase., Scientific Reports, 3, 1046. doi:10.1038/srep01046 [doi]

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Leporq, B., Lambert, S. A., Ronot, M., Boucenna, I., Colinart, P., Cauchy, F., . . . Van Beers, B. E. (2016)., Hepatic fat fraction and visceral adipose tissue fatty acid composition in mice: Quantification with 7.0T MRI., Quantification with 7.0T MRI. Magnetic Resonance in Medicine, 76(2), 510-518. doi:10.1002/mrm.25895 [doi]

Cheng Z, Li C, Khadria A, Zhang Y, Wang LV., High-gain and high-speed wavefront shaping through scattering media., Nat Photonics. 2023 Apr;17(4):299-305. doi: 10.1038/s41566-022-01142-4. Epub 2023 Jan 23.

Hernandez-Gonzalez F, Prats N, Ramponi V, LÃ³pez-DomÃnguez JA, Meyer K, Aguilera M, MuÃ±oz MartÃn MI, MartÃnez D, Agusti A, Faner R, SellarÃ©s J, Pietrocola F, Serrano M., Human senescent fibroblasts trigger progressive lung fibrosis in mice., Aging (Albany NY). 2023 Jul 1;15(14):6641-6657. doi: 10.18632/aging.204825. Epub 2023 Jul 1.

Ramis JM, Blasco-Ferrer M, Calvo J, Villa O, Cladera MM, Corbillo C, GayĂ A, Monjo M., Improved physical and osteoinductive properties of demineralized bone matrix by gelatin methacryloyl formulation, J Tissue Eng Regen Med. 2020 Mar;14(3):475-485. doi: 10.1002/term.3012. Epub 2020 Feb 8.

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Guduric-Fuchs J, Pedrini E, Lechner J, Chambers SEJ, O'Neill CL, Mendes Lopes de Melo J, Pathak V, Church RH, McKeown S, Bojdo J, Mcloughlin KJ, Stitt AW, Medina RJ., miR-130a activates the VEGFR2/STAT3/HIF1? axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia, Mol Ther Nucleic Acids. 2021 Jan 20;23:968-981. doi: 10.1016/j.omtn.2021.01.015. eCollection 2021 Mar 5.

Mc Larney B, Hutter MA, Degtyaruk O, Deán-Ben XL, Razansky D., Monitoring of Stimulus Evoked Murine Somatosensory Cortex Hemodynamic Activity With Volumetric Multi-Spectral Optoacoustic Tomography, Front Neurosci. 2020 Jun 3;14:536. doi: 10.3389/fnins.2020.00536. eCollection 2020.

Kuehner F, Wong M, Straub E, Doorbar J, Iftner T, Roden RBS, Stubenrauch F., Mus musculus papillomavirus 1 E8^E2 represses expression of late protein E4 in basal-like keratinocytes via NCoR/SMRT-HDAC3 co-repressor complexes to enable wart formation in vivo., mBio. 2023 Aug 31;14(4):e0069623. doi: 10.1128/mbio.00696-23. Epub 2023 Jun 29.

Zhang M, Ye J, Xie Z, Yan Y, Wang J, Chen X., Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands, Bioconjug Chem. 2021 Sep 15;32(9):2108-2116. doi: 10.1021/acs.bioconjchem.1c00392. Epub 2021 Sep 6.

Domenici G, Eduardo R, Castillo-Ecija H, Orive G, Montero Carcaboso Á, Brito C., PDX-Derived Ewing's Sarcoma Cells Retain High Viability and Disease Phenotype in Alginate Encapsulated Spheroid Cultures, Cancers (Basel). 2021 Feb 19;13(4):879. doi: 10.3390/cancers13040879.

Chen, Z., Dean-Ben, X. L., Gottschalk, S., & Razansky, D. (2018), Performance of optoacoustic and fluorescence imaging in detecting deep-seated fluorescent agents, Biomedical Optics Express, 9(5), 2229-2239. doi:10.1364/BOE.9.002229 [doi]

Khadria A, Paavola CD, Maslov K, Brown-Augsburger PL, Grealish PF, Lozano E, Blankenship RL, Cao R, Shi J, Beals JM, Oladipupo SS, Wang LV., Photoacoustic imaging of the dynamics of a dye-labeled IgG4 monoclonal antibody in subcutaneous tissue reveals a transient decrease in murine blood oxygenation under anesthesia., J Biomed Opt. 2023 Nov;28(11):116002. doi: 10.1117/1.JBO.28.11.116002. Epub 2023 Nov 30.

Lenz SM, Collins JH, Ray NA, Hagge DA, Lahiri R, Adams LB., Post-exposure prophylaxis (PEP) efficacy of rifampin, rifapentine, moxifloxacin, minocycline, and clarithromycin in a susceptible-subclinical model of leprosy, PLoS Negl Trop Dis. 2020 Sep 16;14(9):e0008583. doi: 10.1371/journal.pntd.0008583. eCollection 2020 Sep.

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Basu, Sankha S; Regan, Michael S; Randall, Elizabeth C; Abdelmoula, Walid M; Clark, Amanda R; Gimenez-Cassina Lopez, BegoĂąa; Cornett, Dale S; Haase, Andreas; Santagata, Sandro; Agar, Nathalie Y R;, Rapid MALDI mass spectrometry imaging for surgical pathology., NPJ precision oncology Vol.3, 2019

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Peterson NC, Berlin AA., Risk Assessment for Use of a Porcine Circovirus-Contaminated Reagent in a Barrier Maintained Rodent Colony, J Am Assoc Lab Anim Sci. 2020 Sep 1;59(5):575-579. doi: 10.30802/AALAS-JAALAS-20-000012. Epub 2020 Jun 30.

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Maloney R, Buuh ZY, Zhao Y, Wang RE., Site-specific antibody fragment conjugates for targeted imaging, Methods Enzymol. 2020;638:295-320. doi: 10.1016/bs.mie.2020.02.023. Epub 2020 Mar 31.

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Immunology

Sanz-Ortega, Laura; Rojas, José M; Marcos, Ana; Portilla, Yadileiny; Stein, Jens V; Barber, Domingo F;, T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field., Journal of nanobiotechnology Vol.17, 2019

Rhoden, J. J., Dyas, G. L., & Wroblewski, V. J. (2016)., A modeling and experimental investigation of the effects of antigen density, binding affinity, and antigen expression ratio on bispecific antibody binding to cell surface targets, The Journal of Biological Chemistry, 291(21), 11337-11347. doi:10.1074/jbc.M116.714287 [doi]

O'Leary, M. P., Warner, S. G., Kim, S. I., Chaurasiya, S., Lu, J., Choi, A. H., . . . Chen, N. G. (2018)., A novel oncolytic chimeric orthopoxvirus encoding luciferase enables real-time view of colorectal cancer cell infection., Molecular Therapy Oncolytics, 9, 13-21. doi:10.1016/j.omto.2018.03.001 [doi]

Di Pompo G, Errani C, Gillies R, Mercatali L, Ibrahim T, Tamanti J, Baldini N, Avnet S., Acid-Induced Inflammatory Cytokines in Osteoblasts: A Guided Path to Osteolysis in Bone Metastasis, Front Cell Dev Biol. 2021 May 28;9:678532. doi: 10.3389/fcell.2021.678532. eCollection 2021.

Rios-Doria, J., Harper, J., Rothstein, R., Wetzel, L., Chesebrough, J., Marrero, A., . . . Hollingsworth, R. (2017)., Antibody-drug conjugates bearing pyrrolobenzodiazepine or tubulysin payloads are immunomodulatory and synergize with multiple immunotherapies., Cancer Research, 77(10), 2686-2698. doi:10.1158/0008-5472.CAN-16-2854 [doi]

Zhang S, Zhao L, Guo M, Liu P, Li S, Xie W, Tian AL, Pol JG, Chen H, Pan H, Mao M, Li Y, Zitvogel L, Jin Y, Kepp O, Kroemer G., Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses., J Immunother Cancer. 2023 Jul;11(7). pii: e006785. doi: 10.1136/jitc-2023-006785.

Fusciello, Manlio; Fontana, Flavia; TĂ¤htinen, Siri; Capasso, Cristian; Feola, Sara; Martins, Beatriz; Chiaro, Jacopo; Peltonen, Karita; YlĂśsmĂ¤ki, Leena; YlĂśsmĂ¤ki, Erkko; Hamdan, Firas; Kari, Otto K; Ndika, Joseph; Alenius, Harri; Urtti, Arto; Hirvonen, Jouni T; Santos, HĂŠlder A; Cerullo, Vincenzo;, Artificially cloaked viral nanovaccine for cancer immunotherapy., Nature communications Vol.10, 2019

Rogovskyy, A. S., & Bankhead, T. (2014)., Bacterial heterogeneity is a requirement for host superinfection by the lyme disease spirochete., Infection and Immunity, 82(11), 4542-4552. doi:10.1128/IAI.01817-14 [doi]

Crum RJ, Capella-MonsonÃs H, Chang J, Dewey MJ, Kolich BD, Hall KT, El-Mossier SO, Nascari DG, Hussey GS, Badylak SF., Biocompatibility and biodistribution of matrix-bound nanovesicles in vitro and in vivo., Acta Biomater. 2023 Jan 1;155:113-122. doi: 10.1016/j.actbio.2022.11.026. Epub 2022 Nov 22.

Puigdelloses M, Garcia-Moure M, Labiano S, Laspidea V, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, De la Nava D, Ausejo I, Hervás-Stubbs S, Herrador G, Chen Z, Hambardzumyan D, Patino Garcia A, Jiang H, Gomez-Manzano C, Fueyo J, Gállego Pérez-Larraya J, Alonso M., CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models, J Immunother Cancer. 2021 Jul;9(7):e002644. doi: 10.1136/jitc-2021-002644.

Wedekind MF, Miller KE, Chen CY, Wang PY, Hutzen BJ, Currier MA, Nartker B, Roberts RD, Boon L, Conner J, LaHaye S, Kelly BJ, Gordon D, White P, Mardis ER, Cripe TP., Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma, iScience. 2021 Jun 19;24(7):102759. doi: 10.1016/j.isci.2021.102759. eCollection 2021 Jul 23.

Verma B, Wesa A., Establishment of Humanized Mice from Peripheral Blood Mononuclear Cells or Cord Blood CD34+ Hematopoietic Stem Cells for Immune-Oncology Studies Evaluating New Therapeutic Agents, Curr Protoc Pharmacol. 2020 Jun;89(1):e77. doi: 10.1002/cpph.77.

Alvero AB, Fox A, Madina BR, Krady MM, Gogoi R, Chehade H, Nakaar V, Almassian B, Yarovinsky TO, Rutherford T, Mor G., Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory., Cancer Immunol Res. 2023 Dec 11. doi: 10.1158/2326-6066.CIR-23-0127. [Epub ahead of print]

Ahmed MSU, Lord BD, Adu Addai B, Singhal SK, Gardner K, Salam AB, Ghebremedhin A, White J, Mahmud I, Martini R, Bedi D, Lin H, Jones JD, Karanam B, Dean-Colomb W, Grizzle W, Wang H, Davis M, Yates CC., Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling., Cancers (Basel). 2023 Apr 13;15(8). pii: 2282. doi: 10.3390/cancers15082282.

Li M, Wei W, Barnhart TE, Jiang D, Cao T, Fan K, Engle JW, Liu J, Chen W, Cai W., ImmunoPET/NIRF/Cerenkov multimodality imaging of ICAM-1 in pancreatic ductal adenocarcinoma, Eur J Nucl Med Mol Imaging. 2021 Aug;48(9):2737-2748. doi: 10.1007/s00259-021-05216-3. Epub 2021 Feb 3.

Landau S, Newman A, Edri S, Michael I, Ben-Shaul S, Shandalov Y, Ben-Arye T, Kaur P, Zheng MH, Levenberg S., Investigating lymphangiogenesis in vitro and in vivo using engineered human lymphatic vessel networks, Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2101931118. doi: 10.1073/pnas.2101931118.

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Nair, Vidhya R; Malladi, Srinivas;, Mouse Models to Study Natural Killer Cell-Mediated Immunosurveillance and Metastatic Latency., Methods in molecular biology (Clifton, N.J.) Vol.1884, 2019

Hedberg J, Studebaker A, Smith L, Chen CY, Westfall JJ, Cam M, Gross A, Hernandez-Aguirre I, Martin A, Kim D, Dhital R, Kim Y, Roberts RD, Cripe TP, Mardis ER, Cassady KA, Leonard J, Miller KE., Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution., Mol Ther Oncolytics. 2023 Jul 19;30:39-55. doi: 10.1016/j.omto.2023.07.006. eCollection 2023 Sep 21.

Jacobson, O., Li, Q., Chen, H., Niu, G., Kiesewetter, D. O., Xu, L., . . . Chen, X. (2017)., PET-guided evaluation and optimization of internalized antibody-drug conjugates targeting erythropoietin-producing hepatoma A2 receptor., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 58(11), 1838-1844. doi:10.2967/jnumed.117.192245 [doi]

Rega, A., Terlizzi, M., Luciano, A., Forte, G., Crother, T. R., Arra, C., . . . Sorrentino, R. (2013)., Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice., Journal of Immunology (Baltimore, Md.: 1950), 190(5), 2391-2402. doi:10.4049/jimmunol.1202086 [doi]

Hsiao, H. C., Fan, X., Jordan, R. E., Zhang, N., & An, Z. (2018)., Proteolytic single hinge cleavage of pertuzumab impairs its fc effector function and antitumor activity in vitro and in vivo, Breast Cancer Research : BCR, 20(1), 43-018-0972-4. doi:10.1186/s13058-018-0972-4 [doi]

Hutzen, B., Chen, C. Y., Wang, P. Y., Sprague, L., Swain, H. M., Love, J., . . . Cripe, T. P. (2017)., TGF-beta inhibition improves oncolytic herpes viroimmunotherapy in murine models of rhabdomyosarcoma, Molecular Therapy Oncolytics, 7, 17-26. doi:10.1016/j.omto.2017.09.001 [doi]

Gruffaz, M., Vasan, K., Tan, B., Ramos da Silva, S., & Gao, S. J. (2017)., TLR4-mediated inflammation promotes KSHV-induced cellular transformation and tumorigenesis by activating the STAT3 pathway., Cancer Research, 77(24), 7094-7108. doi:10.1158/0008-5472.CAN-17-2321 [doi]

Maitra, R., Augustine, T., Dayan, Y., Chandy, C., Coffey, M., & Goel, S. (2017)., Toll like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer, Oncotarget, 8(21), 35138-35153. doi:10.18632/oncotarget.16812 [doi]

Rogovskyy, A. S., & Bankhead, T. (2013)., Variable VlsE is critical for host reinfection by the lyme disease spirochete, PloS One, 8(4), e61226. doi:10.1371/journal.pone.0061226 [doi]

Oncology

Siddique AB, Kilgore PCSR, Tajmim A, Singh SS, Meyer SA, Jois SD, Cvek U, Trutschl M, Sayed KAE., (-)-Oleocanthal as a Dual c-MET-COX2 Inhibitor for the Control of Lung Cancer, Nutrients. 2020 Jun 11;12(6):1749. doi: 10.3390/nu12061749.

Jiménez-Mora E, Gallego B, Díaz-Gago S, Lasa M, Baquero P, Chiloeches A., (V600E)BRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells, Int J Mol Sci. 2021 Jun 3;22(11):6033. doi: 10.3390/ijms22116033.

Masoodi, K. Z., Ramos Garcia, R., Pascal, L. E., Wang, Y., Ma, H. M., O'Malley, K., . . . Wang, Z. (2013)., 5alpha-reductase inhibition suppresses testosterone-induced initial regrowth of regressed xenograft prostate tumors in animal models., Endocrinology, 154(7), 2296-2307. doi:10.1210/en.2012-2077 [doi]

Yang, Hailing; Shu, Zhang; Jiang, Yongying; Mao, Weiqun; Pang, Lan; Redwood, Abena; Jeter-Jones, Sabrina L; Jennings, Nicholas B; Ornelas, Argentina; Zhou, Jinhua; Rodriguez-Aguayo, Cristian; Bartholomeusz, Geoffrey; Iles, LaKesla R; Zacharias, Niki M; Millward, Steven W; Lopez-Berestein, Gabriel; Le, Xiao-Feng; Ahmed, Ahmed A; Piwnica-Worms, Helen; Sood, Anil K; Bast, Robert C; Lu, Zhen, 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers, Clinical cancer research : an official journal of the American Association for Cancer Research Vol.25, 2019

Marayati R, Bownes LV, Stafman LL, Williams AP, Quinn CH, Atigadda V, Aye JM, Stewart JE, Yoon KJ, Beierle EA., 9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts, Transl Oncol. 2021 Jan;14(1):100893. doi: 10.1016/j.tranon.2020.100893. Epub 2020 Sep 30.

Deng, Y., Wang, Z., Zhang, F., Qiao, M., Yan, Z., Wei, Q., . . . Zhang, J. (2016), A blockade of IGF signaling sensitizes human ovarian cancer cells to the anthelmintic niclosamide-induced anti-proliferative and anticancer activities, Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 39(3), 871-888. doi:10.1159/000447797 [doi]

Kuznik NC, Solozobova V, Lee II, Jung N, Yang L, Nienhaus K, Ntim EA, Rottenberg JT, Muhle-Goll C, Kumar AR, Peravali R, Gräßle S, Gourain V, Deville C, Cato L, Neeb A, Dilger M, Cramer von Clausbruch CA, Weiss C, Kieffer B, Nienhaus GU, Brown M, Bräse S, Cato ACB., A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway, iScience. 2022 Mar 31;25(5):104175. doi: 10.1016/j.isci.2022.104175. eCollection 2022 May 20.

Zhao Y, Wang C, Goel A., A combined treatment with melatonin and andrographis promotes autophagy and anticancer activity in colorectal cancer, Carcinogenesis. 2022 Apr 25;43(3):217-230. doi: 10.1093/carcin/bgac008.

Luderer, M. J., Muz, B., de la Puente, P., Chavalmane, S., Kapoor, V., Marcelo, R., . . . Azab, A. K. (2016), A hypoxia-targeted boron neutron capture therapy agent for the treatment of glioma., Pharmaceutical Research, 33(10), 2530-2539. doi:10.1007/s11095-016-1977-2 [doi]

Tian Q, Zhang P, Wang Y, Si Y, Yin D, Weber CR, Fishel ML, Pollok KE, Qiu B, Xiao F, Chong AS., A novel triptolide analog downregulates NF-kB and induces mitochondrial apoptosis pathways in human pancreatic cancer., Elife. 2023 Oct 25;12. pii: e85862. doi: 10.7554/eLife.85862. [Epub ahead of print]

Shivange G, Mondal T, Lyerly E, Bhatnagar S, Landen CN, Reddy S, Kim J, Doan B, Riddle P, Tushir-Singh J., A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors, Cell Rep. 2021 Nov 2;37(5):109953. doi: 10.1016/j.celrep.2021.109953.

Hight, M. R., Cheung, Y. Y., Nickels, M. L., Dawson, E. S., Zhao, P., Saleh, S., . . . Manning, H. C. (2014)., A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 20(8), 2126-2135. doi:10.1158/1078-0432.CCR-13-2444 [doi]

Dey, J., Kerwin, W. S., Grenley, M. O., Casalini, J. R., Tretyak, I., Ditzler, S. H., . . . Klinghoffer, R. A. (2016), A platform for rapid, quantitative assessment of multiple drug combinations simultaneously in solid tumors in vivo., PloS One, 11(6), e0158617. doi:10.1371/journal.pone.0158617 [doi]

Green, D. J., Orgun, N. N., Jones, J. C., Hylarides, M. D., Pagel, J. M., Hamlin, D. K., . . . Press, O. W. (2014), A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies., Cancer Research, 74(4), 1179-1189. doi:10.1158/0008-5472.CAN-13-1589 [doi]

Yang, Lu; Li, Yun; Bhattacharya, Arup; Zhang, Yuesheng;, A recombinant human protein targeting HER2 overcomes drug resistance in HER2-positive breast cancer., Science translational medicine Vol.11, 2019

Neiveyans, Madeline; Melhem, Rana; Arnoult, Christophe; Bourquard, Thomas; Jarlier, Marta; Busson, Muriel; Laroche, Adrien; Cerutti, Martine; PugniĂ¨re, Martine; Ternant, David; Gaborit, NadĂ¨ge; ChardĂ¨s, Thierry; Poupon, Anne; Gouilleux-Gruart, ValĂŠrie; PĂ¨legrin, Andre; Poul, Marie-Alix;, A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions, mAbs Vol.11, 2019

Santich BH, Cheal SM, Ahmed M, McDevitt MR, Ouerfelli O, Yang G, Veach DR, Fung EK, Patel M, Burnes Vargas D, Malik AA, Guo HF, Zanzonico PB, Monette S, Michel AO, Rudin CM, Larson SM, Cheung NK., A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy, Clin Cancer Res. 2020 Sep 21. doi: 10.1158/1078-0432.CCR-20-2150. Online ahead of print.

Santich BH, Cheal SM, Ahmed M, McDevitt MR, Ouerfelli O, Yang G, Veach DR, Fung EK, Patel M, Burnes Vargas D, Malik AA, Guo HF, Zanzonico PB, Monette S, Michel AO, Rudin CM, Larson SM, Cheung NK., A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy, Clin Cancer Res. 2021 Jan 15;27(2):532-541. doi: 10.1158/1078-0432.CCR-20-2150. Epub 2020 Sep 21.

Pattarawat P, Hunt JT, Poloway J, Archibald CJ, Wang HR., A triple combination gemcitabine?+?romidepsin?+?cisplatin to effectively control triple-negative breast cancer tumor development, recurrence, and metastasis, Cancer Chemother Pharmacol. 2021 Sep;88(3):415-425. doi: 10.1007/s00280-021-04298-y. Epub 2021 May 27.

Roy, L. D., Dillon, L. M., Zhou, R., Moore, L. J., Livasy, C., El-Khoury, J. M., . . . Mukherjee, P. (2017)., A tumor specific antibody to aid breast cancer screening in women with dense breast tissue., Genes & Cancer, 8(3-4), 536-549. doi:10.18632/genesandcancer.134 [doi]

Kim, S. S., Rait, A., Kim, E., Pirollo, K. F., & Chang, E. H. (2015)., A tumor-targeting p53 nanodelivery system limits chemoresistance to temozolomide prolonging survival in a mouse model of glioblastoma multiforme., Nanomedicine : Nanotechnology, Biology, and Medicine, 11(2), 301-311. doi:10.1016/j.nano.2014.09.005 [doi]

Formisano, Luigi; Lu, Yao; Servetto, Alberto; Hanker, Ariella B; Jansen, Valerie M; Bauer, Joshua A; Sudhan, Dhivya R; Guerrero-Zotano, Angel L; Croessmann, Sarah; Guo, Yan; Ericsson, Paula Gonzalez; Lee, Kyung-Min; Nixon, Mellissa J; Schwarz, Luis J; Sanders, Melinda E; Dugger, Teresa C; Cruz, Marcelo Rocha; Behdad, Amir; Cristofanilli, Massimo; Bardia, Aditya; OShaughnessy, Joyce; Nagy, Rebecca J; Lanman, Richard B; Solovieff, Nadia; He, Wei; Miller, Michelle; Su, Fei; Shyr, Yu; Mayer, Ingrid A; Balko, Justin M; Arteaga, Carlos L;, Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer., Nature communications Vol.10, 2019

Li M, Li J, Guo X, Pan H, Zhou Q., Absence of HTATIP2 Expression in A549 Lung Adenocarcinoma Cells Promotes Tumor Plasticity in Response to Hypoxic Stress, Cancers (Basel). 2020 Jun 11;12(6):1538. doi: 10.3390/cancers12061538.

Tansi, F. L., Ruger, R., Bohm, C., Steiniger, F., Kontermann, R. E., Teichgraeber, U. K., . . . Hilger, I. (2017)., Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously., Acta Biomaterialia, 54, 281-293. doi:S1742-7061(17)30203-9 [pii]

Young, N. R., Soneru, C., Liu, J., Grushko, T. A., Hardeman, A., Olopade, O. I., . . . Cohen, E. E. (2015)., Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo., Targeted Oncology, 10(4), 501-508. doi:10.1007/s11523-014-0353-6 [doi]

Ziegler, J., Bastian, A., Lerner, M., Bailey-Downs, L., Saunders, D., Smith, N., . . . Towner, R. A. (2017)., AG488 as a therapy against gliomas., Oncotarget, 8(42), 71833-71844. doi:10.18632/oncotarget.18284 [doi]

Gomes AP, Ilter D, Low V, Endress JE, Fernández-García J, Rosenzweig A, Schild T, Broekaert D, Ahmed A, Planque M, Elia I, Han J, Kinzig C, Mullarky E, Mutvei AP, Asara J, de Cabo R, Cantley LC, Dephoure N, Fendt SM, Blenis J., Age-induced accumulation of methylmalonic acid promotes tumour progression, Nature. 2020 Sep;585(7824):283-287. doi: 10.1038/s41586-020-2630-0. Epub 2020 Aug 19.

Dunn S, Eberlein C, Yu J, Gris-Oliver A, Ong SH, Yelland U, Cureton N, Staniszewska A, McEwen R, Fox M, Pilling J, Hopcroft P, Coker EA, Jaaks P, Garnett MJ, Isherwood B, Serra V, Davies BR, Barry ST, Lynch JT, Yusa K., AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors, Oncogene. 2022 Nov;41(46):5046-5060. doi: 10.1038/s41388-022-02482-9. Epub 2022 Oct 14.

Sun Y, Meyers BA, Czako B, Leonard P, Mseeh F, Harris AL, Wu Q, Johnson S, Parker CA, Cross JB, Di Francesco ME, Bivona BJ, Bristow CA, Burke JP, Carrillo CC, Carroll CL, Chang Q, Feng N, Gao G, Gera S, Giuliani V, Huang JK, Jiang Y, Kang Z, Kovacs JJ, Liu CY, Lopez AM, Ma X, Mandal PK, McAfoos T, Miller MA, Mullinax RA, Peoples M, Ramamoorthy V, Seth S, Spencer ND, Suzuki E, Williams CC, Yu SS, Zuniga AM, Draetta GF, Marszalek JR, Heffernan TP, Kohl NE, Jones P., Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib, Cancer Res. 2020 Nov 1;80(21):4840-4853. doi: 10.1158/0008-5472.CAN-20-1634. Epub 2020 Sep 14.

Zhang, R., Pan, D., Cai, X., Yang, X., Senpan, A., Allen, J. S., . . . Wang, L. V. (2015), alphaVbeta3-targeted copper nanoparticles incorporating an sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment., Theranostics, 5(2), 124-133. doi:10.7150/thno.10014 [doi]

Bush, T. L., Payton, M., Heller, S., Chung, G., Hanestad, K., Rottman, J. B., . . . Radinsky, R. (2013), AMG 900, a small-molecule inhibitor of aurora kinases, potentiates the activity of microtubule-targeting agents in human metastatic breast cancer models, Molecular Cancer Therapeutics, 12(11), 2356-2366. doi:10.1158/1535-7163.MCT-12-1178 [doi]

Asundi, J., Crocker, L., Tremayne, J., Chang, P., Sakanaka, C., Tanguay, J., . . . Firestein, R. (2015), An antibody-drug conjugate directed against lymphocyte antigen 6 complex, locus E (LY6E) provides robust tumor killing in a wide range of solid tumor malignancies., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(14), 3252-3262. doi:10.1158/1078-0432.CCR-15-0156 [doi]

Citron, F., Armenia, J., Franchin, G., Polesel, J., Talamini, R., D'Andrea, S., . . . Baldassarre, G. (2017), An integrated approach identifies mediators of local recurrence in head and neck squamous carcinoma, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(14), 3769-3780. doi:10.1158/1078-0432.CCR-16-2814 [doi]

Zhang, F., Li, Y., Zhang, H., Huang, E., Gao, L., Luo, W., . . . Ji, P. (2017)., Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC)., Oncotarget, 8(8), 12968-12982. doi:10.18632/oncotarget.14673 [doi]

Miles, L. A., Burga, L. N., Gardner, E. E., Bostina, M., Poirier, J. T., & Rudin, C. M. (2017)., Anthrax toxin receptor 1 is the cellular receptor for seneca valley virus., The Journal of Clinical Investigation, 127(8), 2957-2967. doi:10.1172/JCI93472 [doi]

Moody, G., Belmontes, B., Masterman, S., Wang, W., King, C., Murawsky, C., . . . Beltran, P. J. (2016)., Antibody-mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo, International Journal of Cancer, 139(6), 1340-1349. doi:10.1002/ijc.30180 [doi]

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Li, X., Wu, J. B., Chung, L. W., & Huang, W. C. (2015)., Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations., Oncotarget, 6(38), 41018-41032. doi:10.18632/oncotarget.5879 [doi]

Yan, H., Kapoor, V., Nguyen, K., Akers, W. J., Li, H., Scott, J., . . . Hallahan, D. (2016)., Anti-tax interacting protein-1 (TIP-1) monoclonal antibody targets human cancers., Oncotarget, 7(28), 43352-43362. doi:10.18632/oncotarget.9713 [doi]

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Brignole C, Calarco E, Bensa V, Giusto E, Perri P, Ciampi E, Corrias MV, Astigiano S, Cilli M, Loo D, Bonvini E, Pastorino F, Ponzoni M., Antitumor activity of the investigational B7-H3 antibody-drug conjugate, vobramitamab duocarmazine, in preclinical models of neuroblastoma., J Immunother Cancer. 2023 Sep;11(9). pii: e007174. doi: 10.1136/jitc-2023-007174.

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Leal AS, Moerland JA, Zhang D, Carapellucci S, Lockwood B, Krieger-Burke T, Aleiwi B, Ellsworth E, Liby KT., The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer, Cancers (Basel). 2021 Oct 6;13(19):5004. doi: 10.3390/cancers13195004.

Dabaghi M, Quaas R, Hilger I., The Treatment of Heterotopic Human Colon Xenograft Tumors in Mice with 5-Fluorouracil Attached to Magnetic Nanoparticles in Combination with Magnetic Hyperthermia Is More Efficient than Either Therapy Alone, Cancers (Basel). 2020 Sep 9;12(9):2562. doi: 10.3390/cancers12092562.

Martin-Fernandez, M., Valencia, K., Zandueta, C., Ormazabal, C., Martinez-Canarias, S., Lecanda, F., & de la Piedra, C. (2017), The usefulness of bone biomarkers for monitoring treatment disease: A comparative study in osteolytic and osteosclerotic bone metastasis models., Translational Oncology, 10(2), 255-261. doi:S1936-5233(16)30223-6 [pii]

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Kampel L, Goldsmith M, Ramishetti S, Veiga N, Rosenblum D, Gutkin A, Chatterjee S, Penn M, Lerman G, Peer D, Muhanna N., Therapeutic inhibitory RNA in head and neck cancer via functional targeted lipid nanoparticles, J Control Release. 2021 Sep 10;337:378-389. doi: 10.1016/j.jconrel.2021.07.034. Epub 2021 Jul 23.

Barbhuiya, M. A., Mirando, A. C., Simons, B. W., Lemtiri-Chlieh, G., Green, J. J., Popel, A. S., . . . Tran, P. T. (2017)., Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma, Oncotarget, 8(60), 101520-101534. doi:10.18632/oncotarget.21148 [doi]

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Wang X, Veeraraghavan J, Liu CC, Cao X, Qin L, Kim JA, Tan Y, Loo SK, Hu Y, Lin L, Lee S, Shea MJ, Mitchell T, Li S, Ellis MJ, Hilsenbeck SG, Schiff R, Wang XS., Therapeutic Targeting of Nemo-like Kinase in Primary and Acquired Endocrine-resistant Breast Cancer, Clin Cancer Res. 2021 May 1;27(9):2648-2662. doi: 10.1158/1078-0432.CCR-20-2961. Epub 2021 Feb 4.

Jo U, Murai Y, Agama KK, Sun Y, Saha LK, Yang X, Arakawa Y, Gayle S, Jones K, Paralkar V, Sundaram RK, Van Doorn J, Vasquez JC, Bindra RS, Choi WS, Pommier Y., TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor, Mol Cancer Ther. 2022 Jul 5;21(7):1090-1102. doi: 10.1158/1535-7163.MCT-21-1000.

Redko, B., Tuchinsky, H., Segal, T., Tobi, D., Luboshits, G., Ashur-Fabian, O., . . . Gellerman, G. (2017)., Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma, Oncotarget, 8(1), 757-768. doi:10.18632/oncotarget.12748 [doi]

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Theunissen, J. W., Cai, A. G., Bhatti, M. M., Cooper, A. B., Avery, A. D., Dorfman, R., . . . Migone, T. S. (2018)., Treating tissue factor-positive cancers with antibody-drug conjugates that do not affect blood clotting., Molecular Cancer Therapeutics, doi:molcanther.0471.2018 [pii]

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Ostler, K. R., Yang, Q., Looney, T. J., Zhang, L., Vasanthakumar, A., Tian, Y., . . . Godley, L. A. (2012)., Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma., Cancer Research, 72(18), 4714-4723. doi:10.1158/0008-5472.CAN-12-0886 [doi]

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Lingasamy P, Tobi A, Kurm K, Kopanchuk S, Sudakov A, Salumäe M, Rätsep T, Asser T, Bjerkvig R, Teesalu T., Tumor-penetrating peptide for systemic targeting of Tenascin-C, Sci Rep. 2020 Apr 2;10(1):5809. doi: 10.1038/s41598-020-62760-y.

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Yuan, B., Cheng, L., Gupta, K., Chiang, H. C., Gupta, H. B., Sareddy, G. R., . . . Li, R. (2016)., Tyrosine phosphorylation regulates ERbeta ubiquitination, protein turnover, and inhibition of breast cancer., Oncotarget, 7(27), 42585-42597. doi:10.18632/oncotarget.10018 [doi]

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Nguyen, Tu; Kirsch, Brian James; Asaka, Ryoichi; Nabi, Karim; Quinones, Addison; Tan, Jessica; Antonio, Marjorie Justine; Camelo, Felipe; Li, Ting; Nguyen, Stephanie; Hoang, Giang; Nguyen, Kiet; Udupa, Sunag; Sazeides, Christos; Shen, Yao-An; Elgogary, Amira; Reyes, Juvenal; Zhao, Liang; Kleensang, Andre; Chaichana, Kaisorn Lee; Hartung, Thomas; Betenbaugh, Michael J; Marie, Suely K; Jung, Jin G; Wang, Tian-Li; Gabrielson, Edward; Le, Anne;, Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cance, Cell reports Vol.27, 2019

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Richter, K., Paakkola, T., Mennerich, D., Kubaichuk, K., Konzack, A., Kippari, H. A., . . . Kietzmann, T. (2018), USP28 deficiency promotes breast and liver carcinogenesis as well as tumor angiogenesis in a HIF-independent manner., Molecular Cancer Research : MCR, 16(6), 1000-1012. doi:10.1158/1541-7786.MCR-17-0452 [doi]

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Gruslova, A., Cavazos, D. A., Miller, J. R., Breitbart, E., Cohen, Y. C., Bangio, L., . . . Brenner, A. J. (2015)., VB-111: A novel anti-vascular therapeutic for glioblastoma multiforme, Journal of Neuro-Oncology, 124(3), 365-372. doi:10.1007/s11060-015-1853-7 [doi]

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Thomson CS, Pundavela J, Perrino MR, Coover RA, Choi K, Chaney KE, Rizvi TA, Largaespada DA, Ratner N., WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth, Oncogene. 2021 Jun;40(24):4229-4241. doi: 10.1038/s41388-021-01773-x. Epub 2021 Jun 2.

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Surgical

Servetto A, Kollipara R, Formisano L, Lin CC, Lee KM, Sudhan DR, Gonzalez-Ericsson PI, Chatterjee S, Guerrero-Zotano A, Mendiratta S, Akamatsu H, James N, Bianco R, Hanker AB, Kittler R, Arteaga CL., Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER(+) Breast Cancer., Clin Cancer Res. 2021 Aug 1;27(15):4379-4396. doi: 10.1158/1078-0432.CCR-20-3905. Epub 2021 May 19.

Transplantation

Bansal A, Pandey MK, Yamada S, Goyal R, Schmit NR, Jeon R, Nesbitt JJ, Witt TA, Singh RD, Gunderson TM, Boroumand S, Li M, Crespo-Diaz RJ, Hillestad ML, Terzic A, Behfar A, DeGrado TR., [(89)Zr]Zr-DBN labeled cardiopoietic stem cells proficient for heart failure, Nucl Med Biol. 2020 Nov-Dec;90-91:23-30. doi: 10.1016/j.nucmedbio.2020.09.001. Epub 2020 Sep 9.

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Talele S, Zhang W, Oh JH, Burgenske DM, Mladek AC, Dragojevic S, Sarkaria JN, Elmquist WF., Central Nervous System Delivery of the Catalytic Subunit of DNA-Dependent Protein Kinase Inhibitor Peposertib as Radiosensitizer for Brain Metastases, J Pharmacol Exp Ther. 2022 Jun;381(3):217-228. doi: 10.1124/jpet.121.001069. Epub 2022 Apr 3.

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