ApoE knockout rats
Related publications
Atherosclerosis
Sijbesma JWA, van Waarde A, Kristensen S, Kion I, Tietge UJF, Hillebrands JL, Bulthuis MLC, Buikema H, Nakladal D, Westerterp M, Liu F, Boersma HH, Dierckx RAJO, Slart RHJA, Characterization of a novel model for atherosclerosis imaging: the apolipoprotein E-deficient rat, EJNMMI Res. 2023 Dec 11;13(1):106. doi: 10.1186/s13550-023-01055-5.
Berenji Ardestani S, Eftedal I, Pedersen M, Jeppesen PB, Nørregaard R, Matchkov VV., Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats, Sci Rep. 2020 Sep 17;10(1):15296. doi: 10.1038/s41598-020-72338-3.
Berenji Ardestani S, Matchkov VV, Hansen K, Jespersen NR, Pedersen M, Eftedal I., Extensive Simulated Diving Aggravates Endothelial Dysfunction in Male Pro-atherosclerotic ApoE Knockout Rats, Front Physiol. 2020 Dec 23;11:611208. doi: 10.3389/fphys.2020.611208. eCollection 2020.
Wu, Y.; Johnson, G.; Zhao, F.; Wu, Y.; Zhao, G.; Brown, A.; You, S.; Zou, M.-H.; Song, P., Features of Lipid Metabolism in Humanized ApoE Knockin Rat Models, International Journal of Molecular Sciences. 2021; 22(15):8262.
Yang, J. H., Niu, W., Li, Y., & Azadzoi, K. M., Impairment of AMPK-?2 augments detrusor contractions in bladder ischemia, Investigative and Clinical Urology 62, no. 5 (2021): 600.
Nguyen TD, Watanabe A, Burleigh S, Ghaffarzadegan T, Kanklai J, Prykhodko O, Hållenius FF, Nyman M., Monobutyrin and monovalerin improve gut-blood-brain biomarkers and alter gut microbiota composition in high-fat fed apolipoprotein-E-knockout rats., Psychopharmacology (Berl). 2023 Jan;240(1):137-147. doi: 10.1007/s00213-022-06286-3. Epub 2022 Dec 5.
Nakladal, D., Sijbesma, J. W. A., Visser, L. M., Tietge, U. J. F., Slart, R. H. J. A., Deelman, L. E., ... & Buikema, H., Perivascular adipose tissue-derived nitric oxide compensates endothelial dysfunction in aged pre-atherosclerotic apolipoprotein E-deficient rats, Vascular pharmacology (2021): 106945.
Nakladal D, Sijbesma JWA, Visser LM, Tietge UJF, Slart RHJA, Deelman LE, Henning RH, Hillebrands JL, Buikema H., Perivascular adipose tissue-derived nitric oxide compensates endothelial dysfunction in aged pre-atherosclerotic apolipoprotein E-deficient rats., Vascul Pharmacol. 2022 Feb;142:106945. doi: 10.1016/j.vph.2021.106945. Epub 2021 Nov 18.
Cardiovascular
Wu Y, Zhao F, Sure VN, Ibrahim A, Yu C, Carr SM, Song P., Human ApoE2 Endows Stronger Contractility in Rat Cardiomyocytes Enhancing Heart Function, Cells. 2023 Jan 17;12(3):347. doi: 10.3390/cells12030347.
General studies
Waugh CM, Mousavizadeh R, Lee J, Screen HRC, Scott A., Mild hypercholesterolemia impacts achilles sub-tendon mechanical properties in young rats, BMC Musculoskelet Disord. 2023 Apr 12;24(1):282. doi: 10.1186/s12891-023-06375-0.
Neuroscience
Berenji Ardestani, Simin; Matchkov, Vladimir V; Eftedal, Ingrid; Pedersen, Michael;, A Single Simulated Heliox Dive Modifies Endothelial Function in the Vascular Wall of ApoE Knockout Male Rats More Than Females., Frontiers in physiology Vol.10, 2019
Phillips, Evan H; Chang, Mandy S; Gorman, Sydney; Qureshi, Hamna J; Ejendal, Karin F K; Kinzer-Ursem, Tamara L; Blaize, A Nicole; Goergen, Craig J;, Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats., Journal of vascular research Vol.55, 2018
Cornelissen, Anne; Simsekyilmaz, Sakine; Liehn, Elisa; Rusu, Mihaela; Schaaps, Nicole; Afify, Mamdouh; Florescu, Roberta; Almalla, Mohammad; Borinski, Mauricio; Vogt, Felix;, Apolipoprotein E deficient rats generated via zinc-finger nucleases exhibit pronounced in-stent restenosis., Scientific reports Vol.9, 2019
Rune, Ida; Rolin, Bidda; Lykkesfeldt, Jens; Nielsen, Dennis Sandris; Krych, Lukasz; Kanter, Jenny E; Bornfeldt, Karin E; Kihl, Pernille; Buschard, Karsten; Josefsen, Knud; Fels, Johannes Josef; Mortensen, Alan; Christoffersen, Berit; Kirk, Rikke Kaae; Hansen, Axel Kornerup;, Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics., Scientific reports Vol.8, 2018
Hohl, Mathias; Linz, Dominik; Fries, Peter; MĂźller, Andreas; Stroeder, Jonas; Urban, Daniel; Speer, Thimoteus; Geisel, JĂźrgen; Hummel, BjĂśrn; Laufs, Ulrich; Schirmer, Stephan H; BĂśhm, Michael; Mahfoud, Felix;, Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats., Journal of translational medicine Vol.14, 2016
Nguyen TD, Hållenius FF, Lin X, Nyman M, Prykhodko O., Monobutyrin and Monovalerin Affect Brain Short-Chain Fatty Acid Profiles and Tight-Junction Protein Expression in ApoE-Knockout Rats Fed High-Fat Diets, Nutrients. 2020 Apr 24;12(4):1202. doi: 10.3390/nu12041202.
