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You want to preserve the integrity of your research colony’s genetic lineage, but you don’t have the capacity, time, resources or desire to maintain it until some undefined future date. That’s understandable, particularly as the number of genetically altered lines developed and maintained for research in animal facilities continually increases. Laboratories often develop their own strains that are genetically modified for specific purposes. The challenge is that your high value strains often result in continued maintenance even though you may not need them for long periods. Besides, such maintenance may produce excess animals and can be expensive, too.

You can avoid these consequences through Inotiv’s embryology services and:

  • Eliminate maintenance of colonies to sustain available research models
  • Reallocate production space and associated resources to other areas of research priority
  • Preserve the genetic integrity of research models for future colony development
  • Provide insurance against physical, genetic, and pathologic disasters
  • Harvest early stage embryos
  • Preserve a specific number of embryos dependent upon your requirements
  • Store embryos or sperm within our facility, or return all material to your designated facility

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Services offered*:

Service Requirements Project outcome

Embryo cryopreservation using homozygous, heterozygous or wild type females - Mouse and Rat

  • 6-8 donor males (6-27 wk)
  • 35 wild-type donor females (3-4 wk)
  • Genotype and background of donors
  • Approximatively 200-300 embryos
  • In vitro QC
  • Free storage for the first year

Mouse Sperm cryopreservation

  • 2-4 donor males (6-27 wk)
  • Genotype and background of donors
  • Approximately 20-22 straws
  • In vitro fertilization QC (2 cell embryo stage)
  • Free storage for the first year

Storage and Fees

 
  • Free storage for the first year
  • Up to 500 embryos in total
  • Up to 50 straws of sperm in total

Live Birth Quality Control for Mouse or Rat Cryopreserved Embryos

  • 40 embryos, minimum
  • In vivo QC to generate live offspring
  • Viable embryos transferred into recipient animals to generate live offspring
  • Confirmation of embryo viability

Live Birth Quality Control for Mouse Cryopreserved Sperm

  • 2-3 straws of sperm
  • In vitro QC to generate live offspring
  • Viable embryos transferred into reciepient animals to generate ive offspring
  • Confirmation of sperm viability

* The above tables are guidelines to achieve the projected outcome. Your dedicated project manager will work with you to customize a plan that best suits your needs.

Please download our contract breeding and support services brochure  indicating different options.

For more information on our services and to request a quote on your next project, please fill out our breeding questionnaire or contact us in North America at servicesPMG.US@inotiv.com or  in Europe at servicesPMG.EU@inotiv.com.

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